Results 1 to 10 of about 42,544 (264)

Is the function of the HBeAg really unknown? [PDF]

Human Vaccines & Immunotherapeutics, 2019
The immune response to the hepatitis B virus (HBV) vaccine in newborns of hepatitis B e antigen (HBeAg)-positive or HBeAg-negative mothers is the subject of Huang et al. The authors report no correlation between the HBeAg status of the mothers/cord blood
David R. Milich
doaj   +6 more sources

Efficacy of a combination of HBV RNA and HBeAg in predicting HBeAg seroconversion in patients treated with entecavir for 144 weeks [PDF]

International Journal of Infectious Diseases, 2020
Background: In some previous studies, serum hepatitis B virus RNA (HBV RNA) was proposed as an HBV viral marker during therapy. However, the dynamic change of HBV RNA, the correlation of HBV RNA with cccDNA, and the combination of HBV RNA with known HBV ...
Junqi Niu, , Yongfang Jiang
exaly   +6 more sources

Plasma gamma-glutamylglycine predicts the seroconversion of hepatitis B e antigen in patients with chronic hepatitis B [PDF]

Frontiers in Immunology
BackgroundThe seroconversion of hepatitis B e antigen (HBeAg) remains difficult to be completely obtained in the treatment of hepatitis B. This study aimed to characterize the metabolic signatures of HBeAg-positive patients and identify key metabolites ...
Ze-Hua Zhao, Zheng-Jie Qu, Zheng-Jie Qu, Zheng-Jie Qu, Xin-Hua Guo, Xue-Qi Yang, Qi An, Fang-Ming Zhou, Fang-Ming Zhou, Jing-Hui Tian, Jing-Hui Tian, Yu-Chen Fan   +11 more
doaj   +2 more sources

Higher risk of postpartum phase transition to immune-active among HBeAg-positive pregnant women with indeterminate phase [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundUnderstanding the natural history of hepatitis B virus (HBV) infection helps determine the optimal timing of antiviral therapy. However, a gap exists in the literature regarding the dynamics of the natural history of HBV infection in pregnant ...
Qiao Tang, Chun-Rui Wang, Hu Li, Zhi-Wei Chen, Xiao-Qing Liu, Yun-Ling Xue, Yue Qiu, Nan Cai, Yi Zeng, Peng Hu, Peng Hu   +10 more
doaj   +2 more sources

Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody

Virulence
The clinical significance of the coexistence of hepatitis B e antigen (HBeAg) and antibodies against HBeAg (anti-HBe) in patients with chronic hepatitis B (CHB) remains unclear.
Chao Wu, Rui Huang
exaly   +3 more sources

Peripheral and intrahepatic B-cell subsets contribute to HBeAg seroconversion in patients with chronic hepatitis B [PDF]

Virology Journal
The immunopathogenesis of chronic hepatitis B (CHB) with unclear immune phases hinders functional cure. For highly infectious HBeAg-positive (HBeAg+) patients where functional cure is unattainable, achieving sustained HBeAg seroconversion constitutes the
Jing Zuo, Xue-Qi Yang, Fang-Ming Zhou, Zheng-Jie Qu, Yu-Xin Tian, Jie-Ru Yang, Yu-Chen Fan   +6 more
doaj   +2 more sources

SERUM HSP 70 LEVELS OF CHRONIC HEPATITIS B PATIENTS ARE SUBSTANTIALLY CORRELATED WITH HBsAg [PDF]

Euromediterranean Biomedical Journal, 2020
Heat-shock protein 70 (HSP70) is a stress-induced protein that demonstrates the anti-apoptosis response that ensures the survival of cells. The aim of this study is to investigate the significant correlation of serum HSP70 levels in chronic hepatitis B ...
Awaz Saadi
doaj   +1 more source

Virological significance of HBeAg subtypes (HBeAg/1 and HBeAg/2) in patients with type B hepatitis

Hepatology, 1987
In order to establish the virological significance of HBeAg subtypes (HBeAg/1 and HBeAg/2) during hepatitis B virus infection, HBsAg, HBeAg and hepatitis B virus DNA in serum and HBeAg in liver were determined quantitatively in relation to the detection of HBeAg subtypes in agar gel diffusion.
A, Kanno, H, Ohori, K, Matsuda, H, Nakayama, Y, Miyazaki, M, Ishii, H, Suzuki, M, Ohtsuki, Y, Goto   +8 more
  +7 more sources

Comparison between Quantitative Hepatitis B DNA and HBeAg Positivity to Detect Active Viral Replication among Patients with Hepatitis B infection in a Tertiary Care Hospital

Journal of Pure and Applied Microbiology, 2023
To study the correlation between quantitative Hepatitis B DNA and HBeAg positivity among HBsAg positive patients in a tertiary care hospital. To detect HBsAg, HBeAg levels by CMIA (Chemiluminescent microparticle immunoassay).
V. Preethi, S.S. Jaya Lakshmi, K.V. Leela   +2 more
doaj   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source