Results 1 to 10 of about 49,566 (218)

Entecavir versus Lamivudine for Patients with HBeAg-Negative Chronic Hepatitis B [PDF]

New England Journal of Medicine, 2006
BACKGROUND: Entecavir is a potent and selective antiviral agent that has demonstrated efficacy in phase 2 studies in patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B.
Ching-Lung Lai, Daniel Shouval, Ting-Tsung Chang   +2 more
exaly   +4 more sources

Higher risk of postpartum phase transition to immune-active among HBeAg-positive pregnant women with indeterminate phase [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundUnderstanding the natural history of hepatitis B virus (HBV) infection helps determine the optimal timing of antiviral therapy. However, a gap exists in the literature regarding the dynamics of the natural history of HBV infection in pregnant ...
Qiao Tang, Chun-Rui Wang, Hu Li, Zhi-Wei Chen, Xiao-Qing Liu, Yun-Ling Xue, Yue Qiu, Nan Cai, Yi Zeng, Peng Hu, Peng Hu   +10 more
doaj   +2 more sources

Peripheral and intrahepatic B-cell subsets contribute to HBeAg seroconversion in patients with chronic hepatitis B [PDF]

Virology Journal
The immunopathogenesis of chronic hepatitis B (CHB) with unclear immune phases hinders functional cure. For highly infectious HBeAg-positive (HBeAg+) patients where functional cure is unattainable, achieving sustained HBeAg seroconversion constitutes the
Jing Zuo, Xue-Qi Yang, Fang-Ming Zhou, Zheng-Jie Qu, Yu-Xin Tian, Jie-Ru Yang, Yu-Chen Fan   +6 more
doaj   +2 more sources

TUBB1 promoter methylation is a promising biomarker for predicting HBeAg seroconversion in chronic hepatitis B [PDF]

Microbiology Spectrum
The identification of predictive indices for hepatitis B e antigen seroconversion (HBeAg SC) in patients with chronic hepatitis B (CHB) remains a challenge.
Tong Zhao, Yuna Tang, Yu Sun, Jihui Li, Yuchen Fan, Chao Cui, Shuai Gao, Kai Wang   +7 more
doaj   +2 more sources

SERUM HSP 70 LEVELS OF CHRONIC HEPATITIS B PATIENTS ARE SUBSTANTIALLY CORRELATED WITH HBsAg [PDF]

Euromediterranean Biomedical Journal, 2020
Heat-shock protein 70 (HSP70) is a stress-induced protein that demonstrates the anti-apoptosis response that ensures the survival of cells. The aim of this study is to investigate the significant correlation of serum HSP70 levels in chronic hepatitis B ...
Awaz Saadi
doaj   +1 more source

Comparison between Quantitative Hepatitis B DNA and HBeAg Positivity to Detect Active Viral Replication among Patients with Hepatitis B infection in a Tertiary Care Hospital

Journal of Pure and Applied Microbiology, 2023
To study the correlation between quantitative Hepatitis B DNA and HBeAg positivity among HBsAg positive patients in a tertiary care hospital. To detect HBsAg, HBeAg levels by CMIA (Chemiluminescent microparticle immunoassay).
V. Preethi, S.S. Jaya Lakshmi, K.V. Leela   +2 more
doaj   +1 more source

Serological detection of hepatitis B virus e antigen and TNF-α in a dialysis patient

Medical Journal of Babylon, 2023
Background: The hepatitis B virus (HBV) is responsible for all forms of hepatitis (occult HBV infection [OBI]) endangering the health of the public. The growth, division, and activity of immune cells are governed by chemical mediators called cytokines ...
Aneeda Khraibet Abed, Zaytoon A Alkhafaji, Ali Jaber Abood   +2 more
doaj   +1 more source

Relationships between HBeAg status of patients with chronic hepatitis B and changes in serum TNF-α, viral load and severity of morphological changes in the liver according to non-invasive tests

Patologìâ, 2021
Aim – to investigate the relationship between HBeAg status of patients with chronic hepatitis B and the content of TNF-α in the serum, the level of viral load and the severity of morphological changes in the liver according to non-invasive tests ...
A. B. Khelemendyk, O. V. Riabokon, Yu. Yu. Riabokon, K. V. Kalashnyk   +3 more
doaj   +1 more source

Viral Hepatitis and Rapid Diagnostic Test Based Screening for HBsAg in HIV-infected Patients in Rural Tanzania. [PDF]

, 2013
\ud \ud Co-infection with hepatitis B virus (HBV) is highly prevalent in people living with HIV in Sub-Saharan Africa. Screening for HBV surface antigen (HBsAg) before initiation of combination antiretroviral therapy (cART) is recommended. However, it is
AM Geretti, AP Kourtis, AS Lok, Bernadeta Msongole, BH Tess, Bruno Verhasselt, Christoph Hatz, CJ Hoffmann, CJ Hoffmann, CL Thio, D Nash, E Mossdorf, E Stahel, ED Chan, Emilio Letang, F Randrianirina, Fabian C. Franzeck, Geoffrey Mwaigomole, GV Matthews, J Davies, J Jaroszewicz, J Li, L Martin-Carbonero, L Stabinski, Lars Henning, M Nyirenda, MA Thompson, Manuel Battegay, Marcel Tanner, Marian Hamisi, MC Kew, Omary Abdul, PM Bossuyt, R Weber, Ramadhani Ngwale, TEMS de Vries–Sluijs, TJ Nagu   +36 more
core   +15 more sources

Antiviral Treatment and One-Year Follow-Up of Chronic Hepatitis B Patients in Bandung: An Observational Study

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: Hepatitis B Virus (HBV) is a health problem that has chronically infected 257 million globally. Appropriate therapy is immensely needed to prevent disease progression to cirrhosis and hepatocellular carcinoma (HCC).
Eka Surya Nugraha, Stefanie Hadi Supriami, Nur Atik, Nenny Agustanti, Yudi Wahyudi, Dolvy Girawan, M Begawan Bestari, Siti Aminah Abdurachman   +7 more
doaj   +1 more source