Results 21 to 30 of about 49,566 (218)

Transition to HBeAg-negative chronic hepatitis B virus infection is associated with reduced cccDNA transcriptional activity.

Journal of Hepatology, 2020
BACKGROUND HBeAg seroconversion during the natural history of chronic hepatitis B (CHB) is associated with a strong drop in serum HBV DNA levels and a reduction of intrahepatic covalently closed circular DNA (cccDNA) content.
A. Suslov, Marie-Anne Meier, S. Ketterer, Xueya Wang, S. Wieland, M. Heim   +5 more
semanticscholar   +1 more source

Seroprevalence of Hepatitis B Virus in Pregnant Women at a Tertiary Care Hospital of Eastern India [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Hepatitis B virus is a DNA virus causing hepatitis in humans. It is thought to be responsible for chronic liver diseases in 75% of cases. Besides other routes, vertical transmission from mother to child is an important one.
Archana Sinha, Minu Sharan, S.K. Shahi
doaj   +1 more source

Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B

Gut, 2020
Objective The involvement of HBV DNA integration in promoting hepatocarcinogenesis and the extent to which the intrahepatic HBV reservoir modulates liver disease progression remains poorly understood.
V. Svicher, R. Salpini, L. Piermatteo, L. Carioti, A. Battisti, L. Colagrossi, R. Scutari, M. Surdo, V. Cacciafesta, A. Nuccitelli, N. Hansi, Francesca Ceccherini Silberstein, C. Perno, U. Gill, P. Kennedy   +14 more
semanticscholar   +1 more source

An expert consensus for the management of chronic hepatitis B in Asian Americans. [PDF]

, 2018
BACKGROUND: Hepatitis B virus (HBV) infection is common with major clinical consequences. In Asian Americans, the HBsAg carrier rate ranges from 2% to 16% which approximates the rates from their countries of origin.
Abbas, Abbas, Ahn, Beasley, Beasley, Bisceglie, Bogr, Brown, Buti, Centers for Disease Control, Chae, Chan, Chang, Chang, Chang, Chang, Chang, Chao, Chaung, Chen, Chen, Chen, Chen, Chi, Chien, Choe, Chu, Clemente, Della Corte, European Association for the Study of the Liver, Evans, Fang, Fattovich, Fontana, Fung, Gish, Hadziyannis, Halperin, Hann, Heathcote, Hongthanakorn, Hoofnagle, Hu, Huang, Hung, Hyun, Iino, Iloeje, Jeng, Keeffe, Kim, Komatsu, Konstantinou, Kowdley, Kuo, Kwong, Lai, Lai, Lai, Lai, Lampertico, Lau, Lau, Lee, Lee, Liang, Liaw, Liaw, Liaw, Liew, Lin, Lin, Lin, Liu, Liu, Liu, Lok, Lok, Lok, Loomba, MacLachlan, Manegold, Marcellin, Marcellin, Marcellin, Marcellin, Marcellin, Marcellin, Martin, Martin-Carbonero, Mast, McClune, McMahon, Mitchell, Monte, Murata, Mutimer, Nafa, Nguyen, Nguyen, Nikolopoulos, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Papatheodoridis, Park, Park, Park, Patterson, Perrillo, Perrillo, Pollack, Prati, Qiu, Reijnders, Sarin, Seto, Seto, Sherman, Shim, Shiraki, Sinatra, Sinn, Soriano, Stevens, Takano, Takayama, Takkenberg, Terrault, Thibault, Thio, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tse, Wang, Wedemeyer, Wei, Wen, Wiseman, Wursthorn, Xie, Xu, Yi, Yi, Yu, Yu, Yuen, Yuen, Yuen, Yuen, Yuen, Zhang, Zhang, Zhang, Zou   +173 more
core   +2 more sources

Rapidly decreased HBV RNA predicts responses of pegylated interferons in HBeAg-positive patients: a longitudinal cohort study

Hepatology International, 2020
Background As an important anti-HBV drug, pegylated interferon α (PegIFNα) offers promising clinical efficacy, but biomarkers that accurately forecast treatment responses are yet to be elucidated.
Min Zhang, Guangdi Li, J. Shang, C. Pan, M. Zhang, Zhibiao Yin, Q. Xie, Yanzhong Peng, Q. Mao, Xin-qiang Xiao, Yongfang Jiang, Kaizhong Luo, Yun Xu, Hai Ding, Wenzhou Fan, Vidaurre Diego, M. Pourkarim, E. De Clercq, Guiqiang Wang, G. Gong   +19 more
semanticscholar   +1 more source

Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas [PDF]

, 1996
This paper uses meta-analysis of published data and a deterministic mathematical model of hepatitis B virus (HBV) transmission to describe the patterns of HBV infection in high endemicity areas.
W. J. Edmunds, G. F. Medley, D. J. Nokes, C. J. O'Callaghan, H. C. Whittle, A. J. Hall, Reniers, Sokal, Pearce, Tong, Pongpipat, Gebreselassie, Overby, Prozesky, Swenson, Anderson, Milne, Sobeslavsky, Schweitzer, Shiraki, Barin   +20 more
core   +1 more source

Clinical, epidemiological and virological features of acute hepatitis B in Italy [PDF]

, 2015
Purpose To evaluate the association of hepatitis B virus (HBV) genotypes, basal core promoter (BCP)/precore (PC) and S gene mutations with the clinical-epidemiological characteristics of acute hepatitis B (AHB) in Italy.
Alessandro Remo Zanetti, Alfonso Mele, Andrea Mariano, Claudio Galli, Enea Spada, Gloria Taliani, Luisa Romanò, Maria Elena Tosti, Massimo Clementi, null null, Ornella Zuccaro   +10 more
core   +1 more source

Comparison of antibody response to hepatitis B vaccination in infants with positive or negative maternal hepatitis B e antigen (HBeAg) in cord blood: implication for the role of HBeAg as an immunotolerogen

Human Vaccines & Immunotherapeutics, 2019
Hepatitis B e antigen (HBeAg) has been considered to cause immunotolerance to hepatitis B virus (HBV) in newborn infants after fetal HBeAg exposure.
Hongyu Huang, Mingzhe Ning, Jingli Liu, Jie Chen, Jing Feng, Yimin Dai, Yali Hu, Yi-Hua Zhou   +7 more
doaj   +1 more source

IL28B is associated with outcomes of chronic HBV infection [PDF]

, 2015
Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes.
Chi, Xiumei, Gao, Yanhang, Jiang, Jing, Li, Wanyu, Minuk, Gerald, Niu, Junqi, Pan, Yu, Shi, Xiaodong, Xu, Damo, Yang, Chen, Zhang, Manna, Zhong, Jin   +11 more
core   +1 more source

Predictive significance of serum pgRNA in HBeAg clearance for chronic hepatitis B patients with low HBeAg level after pegylated interferon treatment

Di-san junyi daxue xuebao, 2022
Objective To evaluate the predictive efficacy of serum pregenomic RNA (pgRNA) level in HBeAg clearance for chronic hepatitis B (CHB) patients treated with polyethylene glycol interferon alfa (PEG-IFN-α).
LIU Zhongwei, LIU Ming, GONG Hongmei, WU Yi, MAO Qing   +4 more
doaj   +1 more source