Results 81 to 90 of about 7,521 (213)

Immunomodulatory Function of HBeAg Related to Short-Sighted Evolution, Transmissibility, and Clinical Manifestation of Hepatitis B Virus

Frontiers in Microbiology, 2018
Hepatitis B virus (HBV) infection, a global public health problem can be asymptomatic, acute or chronic and can lead to serious consequences of infection, including cirrhosis, and hepatocellular carcinoma.
Anna Kramvis, Evangelia-Georgia Kostaki, Angelos Hatzakis, Dimitrios Paraskevis   +3 more
doaj   +1 more source

Quantitative HBsAg and HBeAg predict hepatitis B seroconversion after initiation of HAART in HIV-HBV coinfected individuals. [PDF]

PLoS ONE, 2013
OBJECTIVE: Anti-HBe seroconversion and HBsAg loss are important therapeutic endpoints in patients with hepatitis B virus (HBV) infection. Quantitative measures of hepatitis B surface antigen (qHBsAg) and e antigen (qHBeAg) have been identified as ...
Gail V Matthews, Rachel J Ali, Anchalee Avihingsanon, Janaki Amin, Rachel Hammond, Scott Bowden, Sharon R Lewin, Joe Sasadeusz, Margaret Littlejohn, Stephen L Locarnini, Kiat Ruxrungtham, Gregory J Dore   +11 more
doaj   +1 more source

Updates in the treatment of chronic hepatitis B [PDF]

, 2008
published_or_final_versio
Fung, J, Lai, CL, Yuen, MF
core  

Hepatitis B Reactivation in Biologic‐Treated Moderate‐to‐Severe Psoriasis: A Real‐World Cohort Study With 534 Patient‐Years of Follow‐Up

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Psoriasis vulgaris is a chronic immune‐mediated inflammatory disease frequently requiring long‐term biologic therapy. Although biologics targeting TNF‐α and interleukin pathways have revolutionized disease management, they may disrupt antiviral immune surveillance and trigger hepatitis B virus (HBV) reactivation in individuals with prior HBV
Neslihan Demirel Öğüt, Muhammed Numan Sarıtaş, Merve Duğan, Ece Erbağcı, Sema Koç Yıldırım, Simge Ünal Işık, Ece Gökyayla, Suraiya Saleem   +7 more
wiley   +1 more source

Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions [PDF]

, 2010
Recent guidelines of the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver 2008 update of the "Asian-Pacific consensus statement on the ...
Sang Hoon Ahn, Henry L. Y. Chan, Pei-Jer Chen, Jun Cheng, Mahesh K. Goenka, Jinlin Hou, Seng Gee Lim, Masao Omata, Teerha Piratvisuth, Qing Xie, Hyung Joon Yim, Man-Fung Yuen, YF Liaw, ASF Lok, European Association for the Study of the Liver, EB Keeffe, MJ Tong, MF Yuen, CL Lai, KH Han, F Zoulim, HL Chan, G Chen, CJ Chen, MF Yuen, M Sherman, MF Yuen, HL Chan, HI Yang, HL Chan, JH Kao, MF Yuen, HL Chan, ZL Fang, Y Tanaka, MK Osborn, PSY Tsang, JY Park, BK Park, DI Tai, GL Wong, GL Wong, J Fung, HC Kim, R Kariv, A Piton, D Prati, YS Hsu, M Lai, ASF Lok, HL Chan, CJ Chu, HJ Yuan, HL Chan, P Bedossa, M Omata, KH Han, M Pinzani, CT Wai, PE Chang, AY Hui, HS Kim, SU Kim, M Friedrich-Rust, JA Talwalkar, P Marcellin, HL Chan, DY Kim, A Kettaneh, J Foucher, B Coco, SM Domchek, G L’Italien, CJ Chen, J Fung, RG Gish, P Marcellin, CT Yeh, HI Yang, YF Liaw, RN Chien, BC Song, SK Fung, HL Chan, RN Chien, SJ Hadziyannis, P Marcellin, MF Yuen, SH Ahn, MF Yuen, CM Chu, TT Chang, SJ Hadziyannis, YS Kim, S Momosaki, RD Fleischer, YF Liaw, P Marcellin, JW Shin, RG Gish, HL Chan   +100 more
core   +3 more sources

Hepatitis B Virus Genomic Variability & HBV‐Related Disease Outcomes: A Molecular Epidemiology Perspective

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT HBV infection remains a major global health challenge, characterized by diverse genotypes with distinct geographical distributions and clinical outcomes. Comprehensive analysis of HBV genomic variability and its association with disease progression is essential for improving clinical management and public health strategies. This study aimed to
Maria Bousali, George Papatheodoridis, Magdalini Bletsa, Dimitrios Paraskevis, Timokratis Karamitros   +4 more
wiley   +1 more source

A cost utility and cost effectiveness analysis of different oral antiviral medications in patients with HBeAg-Negative chronic hepatitis B in Iran: an economic microsimulation decision model [PDF]

, 2016
Background: Although hepatitis B infection is the major cause of chronic liver disease in Iran, no studies have employed economic evaluations of the medications used to treat Iranian patients with chronic hepatitis B (CHB).
Alavian, Seyed Moayed, Javanbakht, Mehdi, Kebriaeezadeh, Abbas, Keshavarz, Khosro, Keshvari, Maryam, Lotfi, Farhad, Meshkini, Amir Hashemi, Nikfar, Shekoufeh, Rezaei Hemami, Mohsen, Sari, Ali Akbari   +9 more
core   +1 more source

Adaptive Evolution and Distinct Mutation Signatures of Full‐Length HBV Quasispecies in HBeAg‐Negative Chronic Hepatitis B

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
HBeAg‐negative chronic hepatitis B harbors a highly heterogeneous HBV quasispecies shaped by region‐specific selection. Adaptive strategies underpinning viral persistence include: BCP/PreC mutations supporting replication, PreS/S mutations enabling immune evasion, and overlapping Pol/S mutations maintaining viral fitness.
Changhui Wu, Fengwei Liu, Xiao Li, Xiaojin Li, Hui Li, Sihang Zhang, Xiaohui Yan, Taicheng Zhou, Jia Wei   +8 more
wiley   +1 more source

The natural history of chronic hepatitis B infection [PDF]

, 1997
Chronic hepatitis B infection is a global health problem that affects about 300 million people. Of these, 75% are Chinese. Most Chinese who become chronic carriers, contract the virus during the perinatal period.
Lai, CL, Lau, GKK, Wu, PC
core  

Role of hepatitis B virus genotypes in chronic hepatitis B exacerbation [PDF]

, 2003
Hepatitis B virus (HBV) genotypes and precore and core promoter mutations were determined in 318 patients with HBV. Patients infected with HBV genotype B had a higher median alanine aminotransferase level and bilirubin level and a lower median albumin ...
Chan, AOO, Lai, CL, Sablon, E, Wong, BCY, Wong, DKH, Yuan, HJ, Yuen, MF   +6 more
core   +1 more source