Results 51 to 60 of about 136,614 (358)

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

prevalence of hepatitis B among thalassemic patients in Kerman [PDF]

Journal of Kerman University of Medical Sciences, 1997
A prospective case control study was carried out to evaluate the prevalence of HBsAg in 129 thalassemic patients and 113 children as a control group.ELISA was used for serologic investigations.
A.A Vahidi, A Ahmadi, Y Nikiyan
doaj  

Elevation of BSF-2 Level in Serum of Patients with Hepatitis B Virus

Медицинская иммунология, 2021
Background: Hepatitis B is the main infection of the injured liver for humans. Inflammation of the liver is caused by hepatitis viruses may lead to cirrhosis and hepatocellular carcinoma.
Ali A. Dawood, Mahmood A. A. Altobje, Zeyad T. Alrassam   +2 more
doaj   +1 more source

The Serumal Concentration of Hbsag in Patiets with Chb/hiv Co-infection Comparing with Chb Mono-infection in the Different Phases of Natural Course of Chronic Hepatitis В [PDF]

, 2016
The prevalence and inclination to chronization of viral hepatitis B is 3 – 5 times higher in patients with HIV-infection than in HIV-negative ones. The natural clinical course of chronic hepatitis B (CHB) in patients with HIV has the features, connected ...
Melnyk, T. (Tetiana), Moroz, L. (Larisa)
core  

Persistence of extrahepatic hepatitis B virus DNA in the absence of detectable hepatic replication in patients with baboon liver transplants [PDF]

, 1995
The presence of hepatitis B virus (HBV) DNA in extrahepatic tissues has been well documented. Whether HBV DNA can persist in extrahepatic tissues for long periods of time in the absence of replication in the liver has not been determined previously ...
Davidson, Dejean, Hadchouel, Halpern, Hosoda, Jilbert, Korba, Korba, Lake, Lamelin, Lazizi, Leung, Mason, Mason, Perrillo, Pontisso, Starzl, Starzl, Todo, Yoffe   +19 more
core   +1 more source

Comparison of Anatomical and Non‐Anatomical Resection in Low Microvascular Invasion Risk Solitary Hepatocellular Carcinoma ≤ 5 cm

Annals of Gastroenterological Surgery, EarlyView.
We evaluated whether anatomical resection (AR) provides an oncological benefit over non‐anatomical resection (NAR) in solitary hepatocellular carcinoma ≤ 5 cm without predicted microvascular invasion or intrahepatic metastasis, identified by preoperative DCP ≤ 150 mAU/mL.
Norifumi Iseda, Shinji Itoh, Kyohei Yugawa, Shohei Yoshiya, Takashi Motomura, Takeo Toshima, Tomoharu Yoshizumi   +6 more
wiley   +1 more source

Prevalence of HBe Ag and LFT Survey in HBsAg Positive Blood Donors in Kerman [PDF]

Journal of Kerman University of Medical Sciences, 2003
The hepatitis-B virus (HBV) is one of the most common chronic pathogens in the world. More than 2 billions of world population have been exposed to this virus and 350 millions of them (5% of world population) are chronic carriers of HBV.
M.J Zahedi, S Darvish-Moghaddam, M Haiatbakhsh, H Ferdowsi, L Mozafarian   +4 more
doaj  

Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus [PDF]

, 1985
A DNA sequence encoding the entire pre-S2 region (amino acids 120-174; serotype ayw) of human hepatitis B virus envelope protein has been inserted into the lacZ gene of the plasmid pSKS105 yielding a recombinant, pWS3.
Acs, George, Christman, Judith K., Kent, Stephen B. H., Neurath, A. Robert, Offensperger, Wolf, Price, Peter, Strick, Nathan, Wahl, Silke   +7 more
core   +1 more source

CRISPR/Cas9‐mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV‐positive hepatocellular carcinoma cells

Journal of Cellular Biochemistry, 2018
Chronic hepatitis B virus (HBV) infection remains the most common risk factor for hepatocellular carcinoma (HCC). High HBV surface antigen (HBsAg) levels are highly correlated with hepatocarcinogenesis and HBV‐associated HCC development.
Jia Song, Xiaochao Zhang, Qianyun Ge, Chaoyi Yuan, L. Chu, Hui-fang Liang, Z. Liao, Qiu-meng Liu, Zhanguo Zhang, Bi-xiang Zhang   +9 more
semanticscholar   +1 more source

Surgical Outcomes and Recurrence Management in Borderline Resectable Hepatocellular Carcinoma: Implications for Multidisciplinary Strategies

Annals of Gastroenterological Surgery, EarlyView.
Multivariate analysis identified that up‐to‐7 out (p < 0.001), lymph node metastasis (p < 0.001), and non‐anatomical resection (p = 0.02) were independent predictors of cancer recurrence, while older age (p = 0.01), Child‐Pugh B (p < 0.001), up‐to‐7 out (p = 0.01), macrovascular invasion (p = 0.01), and lymph node metastasis (p < 0.001) were ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Yuto Yamahata, Shinji Onda, Yoshihiro Shirai, Masashi Tsunematsu, Tomohiko Taniai, Michinori Matsumoto, Toru Ikegami   +9 more
wiley   +1 more source