Results 51 to 60 of about 45,532 (172)

Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

Hepatology Research, EarlyView.
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki, Satoshi Shirahama, Takahiro Yasaka, Shota Yamaguchi, Masashi Mizokami, Junko Tanaka, Hiroaki Okamoto, Hiroshi Yatsuhashi   +7 more
wiley   +1 more source

Design, Synthesis, Physicochemical and Immunological Characterization of Dendrimer-HBsAg Conjugate

Vaccine Research, 2014
Manufacturing new Hepatitis B virus vaccines, specifically by the use of nanoparticles, is of high global interest. In this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis B virus’ surface antigen (HBsAg) was generated by ...
Mohammad Sadeq Khosravy, Mehdi Shafiee Ardestani, Reza Ahangari Cohan, Delaram Doroud, Safieh Amini, Seyed Bahman Momen, Seyed Mohammad Atyabi, Hossien Heydari, Rohollah Vahabpour   +8 more
doaj  

Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Hastanesi Kan Donörlerinde HCV, HIV ve HBV Seroprevalansı

Sakarya Tıp Dergisi, 2017
Amaç: Çoğu viral olmak üzere çeşitli enfeksiyon etkenlerinin alıcıya bulaşması kan transfüzyonlarının en sık karşılaşılan komplikasyonudur. Bu etkenler asemptomatik, akut, kronik ve latent enfeksiyonlara neden olabilirler.
Uğur Tüzüner, Mehmet Özdemir, Bahadır Feyzioğlu, Mahmut Baykan   +3 more
doaj   +1 more source

Suppression of Indoleamine 2,3‐Dioxygenase Enhances Immune Responses to the Therapeutic Vaccine for Chronic Hepatitis B

Hepatology Research, EarlyView.
Indoleamine 2,3‐dioxygenase (IDO) activity modulates immune responses to the therapeutic HBV vaccine NASVAC. Genetic or pharmacological suppression of IDO enhanced vaccine efficacy in mice, and lower serum kynurenine levels predicted favorable responses in humans, suggesting IDO as both a therapeutic target and a biomarker.
Yohei Shirakami, Soranobu Ninomiya, Takayasu Ideta, Ayumu Kanbe, Toshihide Maeda, Daisuke Minowa, Daisuke Taguchi, Masaya Kubota, Hiroyasu Sakai, Kenji Imai, Yasuko Yamamoto, Hiroyasu Ito, Kuniaki Saito, Osamu Yoshida, Yoichi Hiasa, Masahito Shimizu   +15 more
wiley   +1 more source

Hyperendemicity and genotype diversity of hepatitis B virus among patients attending the University of Abuja Teaching Hospital, Nigeria

GMS Hygiene and Infection Control
Background: Hepatitis B virus (HBV) infection remains a significant global public health issue, particularly in sub-Saharan Africa, due to inadequate healthcare and research into its genetic epidemiology. This study aims to determine the frequency of HBV
Ugwu, Chinwe Ndidi, Dangana, Amos, Suleiman Chunta, Hassan, Akyala Adamu, Ishaku, Miri, Nanpon, Leviticus Dansura, Mangpin, Samuel, Bwede Eugene, Villeng Gagari, Felix, Adeyemi Ojo, Johnson, Gyang, Nyiri Miriam, Uzoebo, Nkiruka Lynda, Nanbol, Helen Daniel, Nyinishu, Gabriel Bernice, Barde, Aisha Daminso, Abdullahi, Idris Nasir   +14 more
doaj   +1 more source

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

HIV Medicine, EarlyView.
Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito, Andrea Marongiu, Antonella Cano, Mariangela Puci, Agnese Colpani, Susanna Maria Nuvoli, Maria Grazia Catte, Giulia Moi, Maria Antonietta Deledda, Sergio Uzzau, Giovanni Sotgiu, Franca Deriu, Angela Spanu, Giordano Madeddu   +13 more
wiley   +1 more source

Real‐world use of second‐generation integrase strand transfer inhibitors (INSTI) as switch therapy in the prospective ANRS‐CO3‐AquiVIH‐NA cohort

HIV Medicine, EarlyView.
Abstract Objectives To characterize real‐world treatment switching in France to bictegravir (BIC or B) or dolutegravir (DTG)‐based regimens with a focus on treatment persistence, effectiveness (HIV‐1 RNA ≤50 copies/ml) and particular attention to the prevalence and incidence of comorbidities. Methods People living with HIV from the prospective ANRS‐CO3‐
O. Leleux, A. Peyrouny‐Mazeau, A. Perrier, M. Hessamfar, G. Le Moal, D. Neau, L. Alleman, C. Cazanave, E. Lazaro, P. Duffau, A. Riché, Y. Gérard, G. Barrière, S. Reigadas, M.‐A. Vandenhende, F. Bonnet   +15 more
wiley   +1 more source

High Intrahepatic cccDNA in Resolved HBV Infection: Insights From Living Donor Liver Transplantation With Anti‐HBc‐Positive Grafts

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Aim In hepatitis B surface antigen (HBsAg)‐negative recipients with antibody to hepatitis B core antigen (anti‐HBc)‐positive liver grafts, hepatitis B virus (HBV) can be reactivated under post‐transplant immunosuppression. We recently reported a median intrahepatic covalently closed circular DNA (cccDNA) level of 238 copies/μg in HBsAg ...
Sung Kwan Bae, Nobuhisa Akamatsu, Akihiko Ichida, Yujiro Nishioka, Yoshinori Inagaki, Nozomi Miyake, Takeshi Takamoto, Yoshikuni Kawaguchi, Sumihito Tamura, Junichi Arita, Junichi Kaneko, Motoyuki Otsuka, Yasuhito Tanaka, Hiroshi Yotsuyanagi, Kyoji Moriya, Kiyoshi Hasegawa   +15 more
wiley   +1 more source

Plastics and labor: The case of disposable medical plastics

Medical Anthropology Quarterly, EarlyView.
Abstract Plastics are ubiquitous in the contemporary practice of medicine, where they are tied to notions of hygiene and quality of care. However, when plastics first infiltrated global medical practice, they did so because of considerations related to patient comfort and durability.
Gauri Pathak
wiley   +1 more source

Comparing specificity and seroconversion sensitivity among major blood screening assays for human immunodeficiency virus and viral hepatitis

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Accurate detection of transfusion‐transmissible infections, such as human immunodeficiency virus (HIV) and hepatitis C and B viruses (HCV/HBV), is critical to ensure blood safety, and screening assays must demonstrate high specificity and sensitivity.
Monica Chaves, Martina Schaetzl, Florina Pessl   +2 more
wiley   +1 more source