Results 101 to 110 of about 342,150 (384)

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon.

Gastroenterology, 2018
BACKGROUND & AIMS Hepatitis C virus (HCV) infection is sensitive to interferon (IFN)-based therapy, whereas hepatitis B virus (HBV) infection is not. It is unclear whether HBV escapes detection by the IFN-mediated immune response or actively suppresses ...
P. Mutz, P. Metz, Florian A. Lempp, S. Bender, B. Qu, K. Schöneweis, S. Seitz, T. Tu, A. Restuccia, J. Frankish, Christopher Dächert, B. Schusser, R. Koschny, G. Polychronidis, P. Schemmer, K. Hoffmann, T. Baumert, M. Binder, S. Urban, R. Bartenschlager   +19 more
semanticscholar   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Impact of Financial Market uncertainty and Financial Crises on Dynamic Stock—Foreign Exchange Market Correlations: A New Perspective

SAGE Open
This study explores how uncertainties in domestic financial markets, including stocks, bonds, and exchange rates, as well as global crises like the subprime mortgage and European sovereign debt crises, affect the dynamic correlation between the ...
Farid Irani, Abobaker Al.Al. Hadood, Korhan K. Gökmenoğlu, Seyed Alireza Athari   +3 more
doaj   +1 more source

SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Viruses, 2020
Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and ...
Hua Yang, Jiayin Mo, Qi Xiang, Peiyi Zhao, Yunting Song, Ge Yang, Kailang Wu, Yingle Liu, Weiyong Liu, Jianguo Wu   +9 more
doaj   +1 more source

Prevalence of HIV, HBV and Chlamydia infections in Cameroonian University context: case of the University of Dschang, in the Western Region [PDF]

, 2015
Introduction: In sub-Saharan Africa HIV infection remains largely epidemic, whereas HBV infection is highly endemic (>8%). In Cameroon, HIV prevalence is 4.3%. Concerning HBV and chlamydia infections, their prevalence are both ≥10%.
Colizzi, V., Djeunang Dongho, G. B., Donfack, J. H., Fokam, J., Mbongue, G., Mpoame, M., Nkamedjie, P. P. M., Onohiol, J. F., Russo, G., Sanou Sobze, M., Watcho, P.   +10 more
core  

The Role of cccDNA in HBV Maintenance

Viruses, 2017
Chronic hepatitis B virus (HBV) infection continues to be a major health burden worldwide; it can cause various degrees of liver damage and is strongly associated with the development of liver cirrhosis and hepatocellular carcinoma.
L. Allweiss, M. Dandri
semanticscholar   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Assessment of the Prevalence of Markers of Monoinfection with Hepatitis C Virus and Coinfection with Hepatitis C and B Viruses among the Personnel of Medical Institutions of an Endemic Region

Эпидемиология и вакцинопрофилактика
Relevance. Parenteral viral hepatitis B (HBV) and C (HCV) affect not only millions of people, but also healthcare workers due to professional contacts, which lead to the progression of liver pathology and a reduction in medical activity. Numerous studies
M. P. Kostinov, N. A. Magomedova, I. A. Khrapunova, A. V. Linok, E. Yu. Malinnikova, G. I. Alatortseva, L. N. Pritvorova, L. N. Nesterenko, I. I. Amiantova, V. V. Dotsenko, V. Yu. Kabargina, V. B. Polishchuk, M. N. Loktionova, A. A. Besshaposhnikova   +13 more
doaj   +1 more source

Fine Mapping of the MHC Region Identifies Novel Variants Associated with HBV-Related Hepatocellular Carcinoma in Han Chinese

Journal of Hepatocellular Carcinoma, 2021
Haoming Mai,1,* Jiaxuan Chen,1,* Haitao Chen,1,2,* Zhiwei Liu,3,* Guanlin Huang,1 Jialin Wang,1 Qianyi Xiao,4 Weihua Ren,5 Bin Zhou,1 Jinlin Hou,1 Deke Jiang1 1State Key Laboratory of Organ Failure Research, Guangdong Key Laboratory of ...
Mai H, Chen J, Chen H, Liu Z, Huang G, Wang J, Xiao Q, Ren W, Zhou B, Hou J, Jiang D   +10 more
doaj  

Modelling the hepatitis B vaccination programme in prisons [PDF]

, 2005
A vaccination programme offering hepatitis B (HBV) vaccine at reception into prison has been introduced into selected prisons in England and Wales. Over the coming years it is anticipated this vaccination programme will be extended.
Andrews, Nicholas J., Edmunds, W. John, Gay, N. J., Gilbert, R. L., Gill, O. N., Hope, V. D., Piper, M., Sutton, A. J.   +7 more
core   +2 more sources