Designing a therapeutic hepatitis B vaccine to circumvent immune tolerance
Human Vaccines & Immunotherapeutics, 2020 An effective prophylactic hepatitis B virus (HBV) vaccine has long been available but is ineffective for chronic infection. The primary cause of chronic hepatitis B (CHB) and greatest impediment for a therapeutic vaccine is the direct and indirect ...
DC Whitacre +11 more
doaj +1 more source
Impact of MAFLD on HBV-Related Stage 0/A Hepatocellular Carcinoma after Curative Resection [PDF]
, 2021 Yen‐Po Lin +11 more
openalex +1 more source
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
Clinical Anatomy, EarlyView.ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source
Strategies for hepatitis B booster vaccination among children: an 8-year prospective cohort study
Human Vaccines & Immunotherapeutics, 2020 Debate continues regarding the need for a booster vaccination in children who received a universal infant hepatitis B virus (HBV) vaccination. The aim was to explore the need and the strategies for the booster HBV vaccination.
Yan Qiu +10 more
doaj +1 more source
Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection [PDF]
, 2021 Anna D. Kosinska +5 more
openalex +1 more source
Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]
, 2015 Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján +4 more
core +1 more source
CuH‐Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination
ChemistryEurope, EarlyView.The CuH‐catalyzed stereodivergent hydroamination through asymmetric desymmetrization of cyclobutenes has been achieved, yielding a range of trisubstituted aminocyclobutanes with excellent results. A series of subsequent transformations, including the first asymmetric synthesis of two pharmaceutically active molecules, have been realized, and density ...
Xiang Lei +8 more
wiley +1 more source
Nepal Journal of Biotechnology, 2018 Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections lead to chronic diseases and are the most common causes of liver cirrhosis and cancer in developing countries like Nepal.
Gyanendra Bikram Shah +4 more
doaj +1 more source
Seroprevalence Of Hepatitis-b Virus In Mid And Far Western Region In Nepal [PDF]
, 2012 Hepatitis B is significant health problems that might involve the late sequel of liver cirrhosis and hepatocellular carcinoma. The present study aimed to know the seroprevalence of hepatitis B virus (HBV) in mid and far western region in Nepal with ...
H, S. A. (Siddiqui) +3 more
core
Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers
OncoTarget, 2018 Integration of Hepatitis B virus (HBV) into the human genome can cause genetic instability, leading to selective advantages for HBV-induced liver cancer. Despite the large number of studies for HBV integration into liver cancer, little is known about the
Mayuko Furuta +22 more
semanticscholar +1 more source