Hbv - Open Access .click

Results 301 to 310 of about 325,525 (350)

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2005
The study of hepatitis B virus (HBV) kinetics during antiviral therapy contributes to understanding the mechanisms of infection, treatment antiviral effects and treatment failures. HBV DNA kinetics have been poorly characterized in HBeAg-negative chronic hepatitis B (CHB) patients.
openaire +1 more source

Phenotype and function of HBV-specific T cells is determined by the targeted epitope in addition to the stage of infection

Gut, 2018
Objective Chronic HBV infection affects more than 250 million people worldwide and remains a global healthcare problem in part because we lack curative treatment.
Ruben C. Hoogeveen +16 more
semanticscholar +1 more source

Treatment options in HBV

Journal of Hepatology, 2006
The available evidence on interferon-alpha (IFN) treatment for chronic hepatitis B is sufficient to conclude that in patients with HBeAg positive chronic hepatitis, standard IFN therapy significantly improves clearance of HBeAg (number needed to treat [NNT] = 4), loss of HBV-DNA (NNT = 4) and clearance of HBsAg (NNT = 18).
CRAXI, Antonio, ANTONUCCI G, CAMMA', Calogero +2 more
openaire +3 more sources

A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA

Journal of Gastroenterology
Currently, standard treatments for chronic hepatitis B such as nucleos(t)ide analogs (NAs), effectively reduce hepatitis B virus (HBV) loads but rarely result in a functional cure (defined as sustained HBsAg loss). We report the discovery of a novel, 4-pyridone compound, SAG-524, a potent and orally bioavailable small molecule inhibitor of HBV ...
Takehisa Watanabe +6 more
openaire +2 more sources

HBV/HDV COINFECTION

The Lancet, 1987
F. Caredda, S. Antinori, C. Pastecchia, M. Moroni +3 more
openaire +3 more sources

Mechanisms of HBV-induced hepatocellular carcinoma.

Journal of Hepatology, 2016
M. Levrero, J. Zucman‐Rossi
semanticscholar +1 more source

HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production.

Journal of Hepatology, 2017
Xin Yu +9 more
semanticscholar +1 more source

Natural history of acute and chronic hepatitis B: The role of HBV genotypes and mutants.

Best practice & research. Clinical gastroenterology, 2017
Chih‐Lin Lin, J. Kao
semanticscholar +1 more source

HBV vaccination reduces HBV-associated nephropathy

Inpharma Weekly, 2003
openaire +1 more source

Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Immunity, 2021
Yang Cheng +2 more
exaly

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