The Interactions Between HBV and the Innate Immunity of Hepatocytes
Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma.
F. Megahed, Xiaoling Zhou, Pingnan Sun
semanticscholar +1 more source
HBV treatment and pregnancy [PDF]
The management of hepatitis B virus (HBV) infection in pregnancy is complex. Because infection with HBV in infancy often leads to chronic disease, prevention of perinatal or vertical transmission is a major goal. Worldwide, vertical transmission remains the most frequent route of infection, particularly in endemic areas where up to 20% of women of ...
openaire +2 more sources
Health disparities in chronic liver disease
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
wiley +1 more source
Role of antiviral therapy in the natural history of hepatitis B virus-related chronic liver disease [PDF]
Hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, hepatocytes, and the host immune system. Natural history studies of chronic hepatitis B (CHB) infection have shown an association between active viral replication and adverse
Farinati, Fabio +5 more
core +1 more source
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino +14 more
wiley +1 more source
Treatments for HBV: A Glimpse into the Future [PDF]
The hepatitis B virus is responsible for most of the chronic liver disease and liver cancer worldwide. As actual therapeutic strategies have had little success in eradicating the virus from hepatocytes, and as lifelong treatment is often required, new drugs targeting the various phases of the hepatitis B virus (HBV) lifecycle are currently under ...
Bartoli, Alessandra +5 more
openaire +4 more sources
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
THE ENTROPIES OF THE SEQUENCES OF FUZZY SETS AND THE APPLICATIONS OF ENTROPY TO CARDIOGRAPHY [PDF]
In this paper, rstly we have introduced to entropy of sequences of fuzzy sets and given sometheorems about it. Secondly, the waves P and T which appears in electrocardiograms weretransferred to fuzzy sets, by using denition of entropy for sequences of ...
M. şengönül +3 more
doaj
Assessment of protective serum anti-HBsAb levels among previously HBV vaccinated medical residents and its relation to duration and doses of vaccine – single center study [PDF]
Background: Hepatitis B virus (HBV) vaccination is mandatory among health care workers due to high risk of exposure to infection. However, the long-term protective effect of HBV vaccine and assessment of HBV vaccination status by measuring HBsAb remain ...
Mohamed Hashem +5 more
doaj +1 more source
Correlation between hepatitis B G1896A precore mutations and HBeAg in chronic HBV patients [PDF]
Background: Hepatitis B virus (HBV) infection is an important health concern worldwide, with critical outcomes. Hepatitis B e antigen (HBeAg) negative chronic hepatitis B is frequently caused by a mutation (G1896A) in the hepatitis B virus (HBV) precore (
Adli, A.H. +5 more
core +1 more source

