Results 51 to 60 of about 167,368 (308)

Native preparation of immobilized recombinant MBP-HBV-miniP-BAP protein.

, 2022
(A) Domain structure of the MBP-HBV-miniP-BAP protein. The protein is identical to MBP-HBV-miniP-H6 (S5 Fig) except that the C terminal His6 tag is replaced by a Biotin-Acceptor-Peptide (BAP; also known as Avi-tag); its central K residue can be ...
Katharina Dörnbrack (12213595), Michael Nassal (163597), Jürgen Beck (195467)   +2 more
core   +1 more source

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd, Tyler Hamby, Carlo Sacdalan, Somchai Sriplienchan, Pathariya Promensa, Luxenaree Poonpitak, Netsiri Dumrongpisutikul, Eugène Kroon, Sandhya Vasan, Robert Paul, Ferron O'Campo, Lydie Trautmann, Phillip Chan, Serena Spudich, on behalf of the RV254/SEARCH 010 Study Team, Julie Ake, Sandhya Vasan, Lydie Trautmann, Merlin Robb, Trevor Crowell, Donn Colby, Diane Bolton, Shelly Krebs, Leigh Ann Eller, Morgane Rolland, Rasmi Thomas, Dominic Paquin Proulx, Suteeraporn Pinyakorn, Tyler Hamby, Mark de Souza, Ellen Turk, Amber Moodley, Gerald Quarles, Jintanat Ananworanich, Denise Hsu, Victoria Polonis, Nelson Michael, Sheila Peel, COL Eric Garges, Alexandra Schuetz, Siriwat Akapirat, Bessara Nantapinit, Pornsuk Visudhiphan, Saowanit Getchalarat, Nampueng Churikanont, Sangsulee Thamakaison, Somchai Sriplienchan, Carlo Sacdalan, Pathariya Promsena, Luxe‐naree Poonpitak, Eugene Kroon, Nitiya Chomchey, Jintana Intasan, Varaporn Pothipala, Ferron Ocampo, Nittaya Phanuphak, Nipat Teeratakulpisan, Yuwaree Pichitchok, Anchalee Avihingsanon, Opass Putcharoen, Kiat Ruxrungtham, Thanyawee Puthanakit, Sopark Manasnayakorn, Phandee Watanaboonyongcharoen, Rungsun Rerknimitr, Irini Sereti, Daniel Douek, Eli Bortiz, Frank Maldarelli, Mary Kearney, Serena Spudich, Phillip Chan, Lishomwa Ndhlovu, Guinevere Li, Michael Corley, Victor Valcour, Peter Hunt, Jacob Estes, Afam Okoye, Jeff Lifson, Claire Deleage, Nicolas Chomont, Andres Finzi, Lyle McKinnon, Henrik Zetterberg, Robert Siliciano, Robert Paul, Julie Mannarino, Jonathan Li, John Mellors, Josh Cytkor, Dan Barouch, Michael Seaman, Boris Juelg, Alex Shalek, Timothy Schacker, Ashley Haase, Mario Stevenson, Wenjun Li, Arthur Kim, Sharon Lewin, Adam Carrico, Susana Valente, Fred Hutchinson, Josh Schiffer, Guido Ferrari, Beau Ances, Alberto Bosque, Katharine Bar, Killian Pohl, David Ho, Yaoxing Huang, Michael Busch, Mohamed Abdel‐Mohsen, Johanna Gostner, Brian Agan, Fatah Kashanchi, Greg Laird, Kathryn Holroyd   +118 more
wiley   +1 more source

HBsAg loss in chronic hepatitis B patients with an HBsAg decline plateau can be enhanced by intermittent PEG-IFN treatment

Frontiers in Cellular and Infection Microbiology
BackgroundDuring interferon (IFN) treatment patients with chronic hepatitis B (CHB), HBsAg levels often declines to a plateau. This study investigated the HBsAg loss rate in patients receiving continuous IFN treatment after reaching a plateau compared ...
Weihua Cao, Weihua Cao, Si Xie, Hongxiao Hao, Hongxiao Hao, Wen Deng, Wen Deng, Lu Zhang, Lu Zhang, Yao Lu, Yao Lu, Ruyu Liu, Ruyu Liu, Shiyu Wang, Shiyu Wang, Xinxin Li, Xinxin Li, Ziyu Zhang, Ziyu Zhang, Xin Wei, Xin Wei, Zixuan Gao, Zixuan Gao, Linmei Yao, Linmei Yao, Shuojie Wang, Shuojie Wang, Yuanjiao Gao, Yuanjiao Gao, Yujie Wang, Yujie Wang, Mengjiao Xu, Mengjiao Xu, Leiping Hu, Leiping Hu, Yao Xie, Yao Xie, Yao Xie, Minghui Li, Minghui Li, Minghui Li   +40 more
doaj   +1 more source

Hidden dangers-prevalence of blood borne pathogens, hepatitis B, C, HIV and syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study

The Pan African Medical Journal, 2018
INTRODUCTION: Transmissible blood-borne infections are a serious threat to blood transfusion safety in West African countries; and yet blood remains a key therapeutic product in the clinical management of patients.
Emmanuel Edmond Yambasu, Anthony Reid, Philip Owiti, Marcel Manzi, Mariama Jeanne Sia Murray, Ama Kyerewaa Edwin   +5 more
doaj   +1 more source

Proportion and odds ratios of HIV-HBV-HCV co-infections in HIV patients (N = 474).

, 2022
Proportion and odds ratios of HIV-HBV-HCV co-infections in HIV patients (N = 474).
Roshan Chhetry (12191295), Tejendra Pandit (12191292), Lok Bahadur Shrestha (10008254), Abhilasha Sharma (9638364), Basudha Khanal (181181), Saugat Pradhan (12191289), Gopal K. Yadav (12191286)   +6 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Precision treatment and frontier advances of glycyrrhizin preparations in drug-induced liver injury (DILI)

Frontiers in Pharmacology
Drug-induced liver injury (DILI) is an important drug-induced disease in clinical practice, with a complex pathogenesis and challenges in diagnosis and treatment.
Dianya Qiu, Dianya Qiu, Zixuan Gao, Zixuan Gao, Lu Zhang, Lu Zhang, Lu Zhang, Tianyu Ma, Tianyu Ma, Xin Wei, Xin Wei, Ziyu Zhang, Ziyu Zhang, Weihua Cao, Weihua Cao, Xinxin Li, Xinxin Li, Shiyu Wang, Shiyu Wang, Wen Deng, Wen Deng, Yaqin Zhang, Yaqin Zhang, Linmei Yao, Linmei Yao, Shuojie Wang, Shuojie Wang, Yuyong Jiang, Yuyong Jiang, Yuyong Jiang, Yao Xie, Yao Xie, Yao Xie, Minghui Li, Minghui Li, Minghui Li   +35 more
doaj   +1 more source

Amplification efficiency and cost analysis of MP-NAT and ID-NAT in blood samples

Zhongguo shuxue zazhi, 2023
Objective To compare the performance and cost-effectiveness between ID-NAT (individual detection of NAT) mode and MP-NAT (mini-pool nucleic acid test) mode in blood screening, and to provide reference for blood sample detection. Methods The results of 95
Ziyi HE, Guowei HAN, Qingkai CHEN, Qing WANG, Shaobin CHEN, Lin YU   +5 more
doaj   +1 more source

Anti-HBV effect of TAT- HBV targeted ribonuclease

World Journal of Gastroenterology, 2003
To prepare and purify TAT-HBV targeted ribonuclease fusion protein, evaluate its transduction activity and investigate its effect on HBV replication in 2.2.15 cells.The prokaryotic expression vector pTAT containing TR gene was used in transforming E.coli BL21 (DE3) LysS and TR was expressed with the induction of IPTG.
Jin, Ding, Jun, Liu, Cai-Fang, Xue, Wei-Dong, Gong, Ying-Hui, Li, Ya, Zhao   +5 more
openaire   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source