Results 41 to 50 of about 173,141 (216)

Proinflammatory Cytokines and Its Correlation with Liver Injury

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: A persistent infection of hepatitis B virus (HBV) can cause liver cirrhosis and hepatocarcinoma even though the virus itself is non-cytopathic and does not cause cell injury.
Tri Nugraha Susilawati, Winda Rahayuningtyas, Triyanta Yuli Pramana   +2 more
doaj   +1 more source

HBV Immunomics 10X and Smart-seq2 integrated data

, 2023
<p>Here, we established a single-cell RNA-sequencing (scRNA-seq) dataset of HBV immune responses in patients to contribute to a better understanding of the dysregulated immune response in CHB.
François Habersetzer, Thomas F. Baumert, Tobias Nilsson, Nadege Pelletier, Antonio Saviano, Marianne Forkel, Tony Kam-Thong, Klas Hatje, Nadine Kumpesa, Pauline Simo-Noumbissie, Nicolas Giroud   +10 more
core   +1 more source

A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition In Vitro

Viruses, 2020
Immune-suppression driven Hepatitis B Virus (HBV)-reactivation poses serious concerns since it occurs in several clinical settings and can result in severe forms of hepatitis.
Romina Salpini, Lorenzo Piermatteo, Arianna Battisti, Luna Colagrossi, Marianna Aragri, Katia Yu La Rosa, Ada Bertoli, Patrizia Saccomandi, Miriam Lichtner, Massimo Marignani, Sarah Maylin, Constance Delaugerre, Filomena Morisco, Nicola Coppola, Aldo Marrone, Nerio Iapadre, Carlotta Cerva, Stefano Aquaro, Mario Angelico, Loredana Sarmati, Massimo Andreoni, Jens Verheyen, Francesca Ceccherini-Silberstein, Massimo Levrero, Carlo Federico Perno, Laura Belloni, Valentina Svicher   +26 more
doaj   +1 more source

HBV genotypes and response to tenofovir disoproxil fumarate in HIV/HBV-coinfected persons [PDF]

, 2015
BACKGROUND Hepatitis B virus (HBV) genotypes can influence treatment outcome in HBV-monoinfected and human immunodeficiency virus (HIV)/HBV-coinfected patients.
Rickenbach, Martin, Anna-Paola Caminada, Battegay, Manuel, Calmy, A., Martinetti, Gladys, Enos Bernasconi, Martin Rickenbach, Wandeler, Gilles, Cavassini, M., Wandeler, G., Pietro Vernazza, Battegay, M., Vernazza, P., Calmy, Alexandra, Gladys Martinetti, Bernasconi, Enos, Gilles Wandeler, Weber, R., Bruno Ledergeber, Swiss HIV Cohort Study, Rickenbach, M., Rainer Weber, Alexandra Calmy, Ledergeber, B., Bihl, Florian, Martinetti, G., Caminada, A.P., Manuel Battegay, Caminada, Anna-Paola, Florian Bihl, null null, Vernazza, Pietro, Weber, Rainer, Ledergeber, Bruno, Cavassini, Matthias, Matthias Cavassini, Bihl, F., Bernasconi, E., Ledergeber B, Bihl F, Battegay M, Vernazza P, Calmy A, Bernasconi E, Rickenbach M, Caminada AP, Wandeler G, Cavassini M, Martinetti G, Weber R   +49 more
core   +3 more sources

HBsAg loss in chronic hepatitis B patients with an HBsAg decline plateau can be enhanced by intermittent PEG-IFN treatment

Frontiers in Cellular and Infection Microbiology
BackgroundDuring interferon (IFN) treatment patients with chronic hepatitis B (CHB), HBsAg levels often declines to a plateau. This study investigated the HBsAg loss rate in patients receiving continuous IFN treatment after reaching a plateau compared ...
Weihua Cao, Weihua Cao, Si Xie, Hongxiao Hao, Hongxiao Hao, Wen Deng, Wen Deng, Lu Zhang, Lu Zhang, Yao Lu, Yao Lu, Ruyu Liu, Ruyu Liu, Shiyu Wang, Shiyu Wang, Xinxin Li, Xinxin Li, Ziyu Zhang, Ziyu Zhang, Xin Wei, Xin Wei, Zixuan Gao, Zixuan Gao, Linmei Yao, Linmei Yao, Shuojie Wang, Shuojie Wang, Yuanjiao Gao, Yuanjiao Gao, Yujie Wang, Yujie Wang, Mengjiao Xu, Mengjiao Xu, Leiping Hu, Leiping Hu, Yao Xie, Yao Xie, Yao Xie, Minghui Li, Minghui Li, Minghui Li   +40 more
doaj   +1 more source

Hidden dangers-prevalence of blood borne pathogens, hepatitis B, C, HIV and syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study

The Pan African Medical Journal, 2018
INTRODUCTION: Transmissible blood-borne infections are a serious threat to blood transfusion safety in West African countries; and yet blood remains a key therapeutic product in the clinical management of patients.
Emmanuel Edmond Yambasu, Anthony Reid, Philip Owiti, Marcel Manzi, Mariama Jeanne Sia Murray, Ama Kyerewaa Edwin   +5 more
doaj   +1 more source

Glycyrrhizin preparations in liver diseases: a narrative review of mechanisms and therapeutic potential

Frontiers in Pharmacology
Glycyrrhizin preparations (GLPS), derived from Glycyrrhiza uralensis (licorice), are widely used hepatoprotective agents in clinical practice. Their primary active components, 18α- and 18β-glycyrrhetinic acid (GA), are represented by formulations ...
Tianyu Ma, Tianyu Ma, Hongxiao Hao, Hongxiao Hao, Shuojie Wang, Shuojie Wang, Dianya Qiu, Dianya Qiu, Weihua Cao, Weihua Cao, Wen Deng, Wen Deng, Shiyu Wang, Shiyu Wang, Xinxin Li, Xinxin Li, Ziyu Zhang, Ziyu Zhang, Xin Wei, Xin Wei, Linmei Yao, Linmei Yao, Zixuan Gao, Zixuan Gao, Wei Yi, Ruyu Liu, Ruyu Liu, Minghui Li, Minghui Li, Minghui Li   +29 more
doaj   +1 more source

Amplification efficiency and cost analysis of MP-NAT and ID-NAT in blood samples

Zhongguo shuxue zazhi, 2023
Objective To compare the performance and cost-effectiveness between ID-NAT (individual detection of NAT) mode and MP-NAT (mini-pool nucleic acid test) mode in blood screening, and to provide reference for blood sample detection. Methods The results of 95
Ziyi HE, Guowei HAN, Qingkai CHEN, Qing WANG, Shaobin CHEN, Lin YU   +5 more
doaj   +1 more source

Anti-HBV effect of TAT- HBV targeted ribonuclease

World Journal of Gastroenterology, 2003
To prepare and purify TAT-HBV targeted ribonuclease fusion protein, evaluate its transduction activity and investigate its effect on HBV replication in 2.2.15 cells.The prokaryotic expression vector pTAT containing TR gene was used in transforming E.coli BL21 (DE3) LysS and TR was expressed with the induction of IPTG.
Jin, Ding, Jun, Liu, Cai-Fang, Xue, Wei-Dong, Gong, Ying-Hui, Li, Ya, Zhao   +5 more
openaire   +2 more sources

52-week efficacy and safety of telbivudine with conditional tenofovir intensification at week 24 in HBeAg-positive chronic Hepatitis B [PDF]

, 2013
Background and Aims: The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response.
Tawesak Tanwandee (279135), Jorge Daruich, Wattana Sukeepaisarnjaroen, Rashidkhan Pathan, Eduardo Fassio, Fernando Bessone (254729), Suzane K Ono, Daruich, Jorge, Pessôa, Mário Guimarães, Yuhong Dong, Tanwandee, Tawesak, Rashidkhan Pathan (279143), Sukeepaisarnjaroen, Wattana, Mário G Pessôa, Ono, Suzane K., Teerha Piratvisuth (279131), Piyawat Komolmit (279133), Chan, Henry L. Y., Henry L Y Chan, Dong, Yuhong, Piratvisuth, Teerha, Pessôa, Mário G., Mário G. Pessôa (279138), Stefan Zeuzem (22856), Hugo Cheinquer (279142), Stefan Zeuzem, Trylesinski, Aldo, Pathan, Rashidkhan, Bessone, Fernando, Suzane K. Ono (279140), Henry L. Y. Chan (279137), Aldo Trylesinski (279145), Fassio, Eduardo, Piyawat Komolmit, Henry L. Y. Chan, Ono, Suzane Kioko, Komolmit, Piyawat, Jorge Daruich (279141), Hugo Cheinquer, Eduardo Fassio (279139), Cheinquer, Hugo, Chan, Henry, Tawesak Tanwandee, Mário G. Pessôa, Aldo Trylesinski, Suzane K. Ono, Teerha Piratvisuth, Fernando Bessone, Wattana Sukeepaisarnjaroen (279136), Yuhong Dong (279144), Zeuzem, Stefan, Pathan Rashidkhan, Daruich Jorge, Chan Henry L. Y., Cheinquer Hugo, Pessôa Mário G., Tanwandee Tawesak, Trylesinski Aldo, Piratvisuth Teerha, Ono Suzane K., Fassio Eduardo, Sukeepaisarnjaroen Wattana, Zeuzem Stefan, Dong Yuhong, Komolmit Piyawat, Bessone Fernando   +65 more
core   +2 more sources