Inflammatory Mechanisms of HCC Development [PDF]
Cancers, 2020 HCC (hepatocellular carcinoma) is the second leading cause of cancer deaths worldwide, with several etiologic causes, mostly inflammation-associated. Different inflammatory responses in the liver can be triggered by different etiological agents.
M. G. Refolo +4 more
semanticscholar +4 more sources
BMC Infectious Diseases, 2023 Background HIV infection is associated with more rapid progression of some comorbidities. This study assessed the impact of HIV-infection on the presentation and outcome of HCC.
Sara K. Nsibirwa +5 more
doaj +1 more source
Yttrium‐90 Radioembolization for the Treatment of Solitary, Unresectable HCC: The LEGACY Study
Hepatology, 2021 Locoregional therapies, including yttrium‐90 radioembolization, play an important role in the treatment of unresectable HCC. The aim of the LEGACY (Local radioEmbolization using Glass Microspheres for the Assessment of Tumor Control with Y‐90) study was ...
R. Salem +8 more
semanticscholar +1 more source
Immune System and Hepatocellular Carcinoma (HCC): New Insights into HCC Progression
International Journal of Molecular Sciences, 2023 According to the WHO’s recently released worldwide cancer data for 2020, liver cancer ranks sixth in morbidity and third in mortality among all malignancies. Hepatocellular carcinoma (HCC), the most common kind of liver cancer, accounts approximately for
Maria Kotsari +3 more
semanticscholar +1 more source
Emerging Therapies for Hepatocellular Carcinoma (HCC)
Cancers, 2022 Simple Summary Primary liver cancer, also known as Hepatocellular carcinoma (HCC), is considered to be a major global health challenge. Due to delays in diagnosis at early asymptomatic stages, HCC reaches a severe aggressive stage, thereby having a ...
Eesha Chakraborty, D. Sarkar
semanticscholar +1 more source
Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification
Gut, 2022 Objective We previously reported a characterisation of the hepatocellular carcinoma (HCC) immune contexture and described an immune-specific class. We now aim to further delineate the immunogenomic classification of HCC to incorporate features that ...
C. Montironi +28 more
semanticscholar +1 more source
Sugar Alcohols Have a Key Role in Pathogenesis of Chronic Liver Disease and Hepatocellular Carcinoma in Whole Blood and Liver Tissues. [PDF]
, 2020 The major risk factors for hepatocellular carcinoma (HCC) are hepatitis C and B viral infections that proceed to Chronic Liver Disease (CLD). Yet, the early diagnosis and treatment of HCC are challenging because the pathogenesis of HCC is not fully ...
El-Said, Hala +5 more
core +2 more sources
Emerging immunotherapy for HCC: A guide for hepatologists
Hepatology, 2022 HCC is one of the most common cancers worldwide, and the third leading cause of cancer‐related death globally. HCC comprises nearly 90% of all cases of primary liver cancer.
F. Foerster +3 more
semanticscholar +1 more source
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation [PDF]
, 2020 Rationale: Loss of histone macroH2A1 induces appearance of cancer stem cells (CSCs)-like cells in hepatocellular carcinoma (HCC). How CSCs interact with the tumor microenvironment and the adaptive immune system is unclear. Methods: We screened aggressive
Drovakova A. +11 more
core +1 more source
New US device versus imaging US to assess tumor-in-brain
Chinese Neurosurgical Journal, 2020 Background Applying ultrasonic imaging system during surgery requires the poring of saline, performing the measurement, and acquiring data from its display—which requires time and is highly “performer dependent,” i.e., the measure is of a subjective ...
Jacob Halevy-Politch +3 more
doaj +1 more source