Results 151 to 160 of about 219,990 (308)

New therapeutic targets in HCC: Reptin ATPase and HCC senescence

Journal of Hepatology, 2010
Cellular senescence is a process characterized by permanent cell cycle arrest. It is the consequence of the finite proliferative capacity of normal cells (replicative senescence) and the response to stress and damage from exogenous and endogenous sources.
openaire   +2 more sources

AIM-index distinguishes HCC and non-HCC patients.

, 2014
(A) AIM-TB index vs. AIM-ALB index, AIM-PLT index or AIM-AST index in men with or without HCC. TB vs. ALB, PLT or AST are also presented. (B) AIM-ALB index vs. AIM-%PT index in women with or without HCC. ALB vs. %PT is also presented.
Sei Harada (642804), Mayumi Mori (642797), Toshiaki Gunji (547719), Jun Takahashi (464660), Ken-ichi Yamamura (14117), Masanori Abe (421879), Shinji Seto (642806), Kiyohiro Izumino (642802), Yukio Yoshida (642807), Toshihiro Kai (560571), Shin Ohnishi (642805), Tomoko Yamazaki (560572), Mihoko Ban (642798), Takeharu Asano (642801), Kazuhiko Koike (135022), Toru Miyazaki (560574), Kayo Aoyama (642803), Ryosuke Tateishi (135017), Yoichi Hiasa (156596), Maki Maeda (642800), Satoko Arai (560573), Akemi Nishijima (642799), Toru Takebayashi (462027), Ken-ichiro Inoue (65135)   +23 more
core   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

DNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro

Cancer Management and Research, 2020
Yao Huang,1,2 Jianxing Zeng,2 Teng Liu,2 Qingyi Xu,2 Xianglin Song,2 Jinhua Zeng1,2 1Department of Hepatobiliary Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 2Department of Hepatic
Huang Y, Zeng J, Liu T, Xu Q, Song X, Zeng J   +5 more
doaj  

HCC, diet and metabolic factors: Diet and HCC.

Hepatitis monthly, 2011
Hepatocellular carcinoma is the most common primary liver malignancy and is an international public health concern, constituting one of the most deadly cancers worldwide. Infection with hepatitis B virus and hepatitis C virus is a major risk factor for HCC in developed countries.
Maurizio, Montella, Anna, Crispo, Aldo, Giudice   +2 more
openaire   +1 more source

Diagnostic value of serum STIP1 in HCC and AFP-negative HCC

Laboratory Medicine
Abstract Objective This study aimed to investigate the diagnostic value of stress-induced phosphoprotein 1 (STIP1) in serum for hepatocellular carcinoma (HCC) and alpha-fetoprotein (AFP)–negative HCC (ANHC).
Sun, Haiqing, Liu, Ning, Lou, Jinli
openaire   +2 more sources

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

90Y-/166Ho- ‘Radiation lobectomy’ for liver tumors induces abnormal morphology and impaired drainage of peritumor lymphatics

JHEP Reports
Background & Aims: High-dose unilobar radioembolization, or ‘radiation lobectomy’ (RL), is an induction therapy that achieves contralateral future liver remnant hypertrophy while simultaneously irradiating the tumor.
Daan Andel, Lotte van den Bent, Marnix Gerard Ernest Hendrik Lam, Maarten Leonard Johannes Smits, Isaac Quintus Molenaar, Joep de Bruijne, Miangela Marie Laclé, Onno Kranenburg, Inne Hildbrand Max Borel Rinkes, Jeroen Hagendoorn   +9 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source