PGR-mediated transcriptome identifies SOX9 as a critical regulator of progesterone production in human ovulatory follicles. [PDF]
Jeon H +5 more
europepmc +1 more source
Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth +7 more
wiley +1 more source
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang +7 more
wiley +1 more source
Predictors of early response to GnRH and gonadotropin therapy in pediatric patients with suspected dual congenital hypogonadotropic hypogonadism: a retrospective single-center study. [PDF]
Zhang Q +6 more
europepmc +1 more source
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
Electrochemical biosensors: a novel approach for rapid and cost-effective hCG monitoring in gestational trophoblastic tumours. [PDF]
Nur Y +9 more
europepmc +1 more source
Lived Experiences of Pregnancy Loss at Work: Realizing Meaningful Supports
ABSTRACT There is increased focus on pregnancy loss at work over recent years, with many countries introducing or exploring the introduction of statutory leave for pregnancies that end pre‐“viability.” Individual organizations are also introducing their own pregnancy loss policies.
Marita Hennessy +9 more
wiley +1 more source
Choriocarcinoma Histologically Mimicking Epithelioid Trophoblastic Tumor - A Diagnostic Pitfall in Gestational Trophoblastic Neoplasia. [PDF]
Harsono AB +4 more
europepmc +1 more source
Dialysis and Pregnancy: Optimizing Therapy for Best Maternal and Fetal Outcomes
ABSTRACT Pregnancy in women with end‐stage kidney disease (ESKD) requiring dialysis remains high risk, with significant maternal and fetal complications. While fertility rates are markedly reduced in this population, advances in dialysis care and obstetric management have led to increasing reports of successful pregnancies.
Shreepriya Mangalgi, Silvi Shah
wiley +1 more source
Human Chorionic Gonadotropin (hCG)-Induced Remodeling of the Granulosa Cell Exosomal Proteome: Implications for Follicular Communication. [PDF]
Mancini F +12 more
europepmc +1 more source

