Results 141 to 150 of about 70,435 (286)

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell   +3 more
wiley   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida   +7 more
wiley   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

Four Decades of Research at the MADE Site and Beyond: Advancing the Understanding and Modeling of Solute Transport in Heterogeneous Media

open access: yesReviews of Geophysics, Volume 64, Issue 4, December 2026.
Abstract Spatial heterogeneity, manifested as strong variability in hydraulic conductivity (K) within geological formations, exerts a fundamental control on groundwater flow and solute transport. Because K can vary over multiple orders of magnitude in complex three‐dimensional patterns, predicting contaminant plume migration remains a long‐standing ...
Zhilin Guo   +8 more
wiley   +1 more source

Unique Presentation of Metastatic Malignant Germ Cell Tumour Diagnosed on Pleural Effusion Cytology

open access: yes
Cytopathology, EarlyView.
Scarlet Brockmoeller   +3 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2519-2524, November 2026.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland   +4 more
wiley   +1 more source

Rapidly Progressive Metastatic Sertoli Cell Tumor Associated With an Adenomatous Polyposis Coli Mutation: A Case Report and Literature Review

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Sertoli cell tumors are rare testicular sex cord‐stromal tumors, and clinically malignant behavior is uncommon. We report a rapidly progressive metastatic Sertoli cell tumor associated with an APC mutation. Case Presentation A 27‐year‐old man with familial adenomatous polyposis (FAP) presented with painless right scrotal ...
Kotaro Obayashi   +9 more
wiley   +1 more source

Kinderen met hyperthyreoïdie door verhoogd hCG

open access: yes, 2014
We describe two children with hyperthyroidism secondary to elevated hCG levels: one patient with gestational trophoblastic disease and one patient with choriocarcinoma.
van Trotsenburg, A. S. Paul   +3 more
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