Results 131 to 140 of about 70,435 (286)

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

Testosterone Replacement Therapy in Adolescents and Young Adults With Prader‐Willi Syndrome: Efficacy and Effects on Behaviour

Clinical Endocrinology, EarlyView.
ABSTRACT Context Hypogonadism in Prader‐Willi syndrome (PWS) is associated with decreased bone mineral density (BMD) in male adolescents and adults. Testosterone Replacement Therapy (TRT) improves BMD and sexual maturation, but TRT could aggravate pre‐existing challenging behaviour in male patients with PWS.
Wiebe R. Flamman, Demi J. Trueba‐Timmermans, Lionne N. Grootjen, Laura C. G. de Graaff, Joyce M. Geelen, Janielle A. E. M. van der Velden, Edmond H. H. M. Rings, Anita C. S. Hokken‐Koelega, Gerthe F. Kerkhof   +8 more
wiley   +1 more source

Ploidy‐dependent modulation of DNA replication kinetics in Xenopus

The FEBS Journal, EarlyView.
Using an interspecies replication system with Xenopus frog species of different ploidy levels, we investigated how DNA replication adapts to polyploidization. While replication was slower in tetraploid than in diploid nuclei, dodecaploid nuclei unexpectedly replicated faster than tetraploid nuclei. Our findings show that increasing genome size does not
Hemalatha Narassimprakash, Olivier Haccard, Zhen Li, Nicolas Pollet, Kathrin Marheineke   +4 more
wiley   +1 more source

Caregiver sensitivity moderates effects of gestational inflammation on child ADHD symptoms

Journal of Child Psychology and Psychiatry, EarlyView.
Background Increased inflammation during pregnancy may increase the risk for child psychopathology, though prospective data remain preliminary. Child symptoms of attention‐deficit/hyperactivity disorder (ADHD) are particularly important due to ADHD's role as an early precursor of many later forms of externalizing and internalizing problems.
Elinor L. Sullivan, Jessica M. Tipsord, Elizabeth K. Nousen, Julia Williams, Sara Shao, Diana Vazquez Duque, Jennifer M. Loftis, Sarah L. Karalunas, Joel T. Nigg, Hanna C. Gustafsson   +9 more
wiley   +1 more source

A Clinical audit: Prophylactic granulocyte transfusion to prevent severe febrile neutropenia and subsequent infections in paediatric high-risk patients with leukemia

Pediatric Hematology Oncology Journal
Aswathi Gangadharan, Suma TL, Smitha Shekar, Amit D. Galgali, Ashish Dhoot, Jyothi Goutham Kumar, Priyank Tripathi, Intezar Mehdi   +7 more
doaj   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Evaluation of follicular fluid’s Beta-Human chorionic gonadotropin in the follicles of patient undergoing Intracytoplasmic sperm injection: A cross-sectional study

International Journal of Reproductive BioMedicine, 2018
Background: The failure to retrieve oocytes from mature ovarian follicles is referred to as empty follicle syndrome. There is no exact explanation to this problem and it cannot be predicted using ultrasound or serum hormonal levels.
Masoumeh Hajshafiha, Tahere Behrouzi lak, Nasrin Hajiloo, Yaghoub Deldar, Mina Ghorbani, Fedyeh Haghollahi   +5 more
doaj  

Agomelatine ameliorates abortion‐related alterations in rats: Insights from behavioural, biochemical and histological analyses

Experimental Physiology, EarlyView.
Abstract Abortion aetiology is critically linked to increased myometrial contractions and maternal psychological stress. Given the limited efficacy of current therapies such as progesterone, investigating novel therapeutic interventions is essential. Melatonin exerts reproductive benefits.
Mehtap Pervin, Zeynep Dila Oz, Ahmed Sait Bozyil, Orhan Sayin, Husna Batmaz, Serhat Hancer, Salih Burcin Kavak, Nevin Kocaman, Haluk Kelestimur, Emine Kacar   +9 more
wiley   +1 more source

Genomic profiling of pediatric hemato-lymphoid malignancies and inherited bone marrow failure syndrome using next-generation sequencing (NGS): An institutional study

Pediatric Hematology Oncology Journal
Amit D. Galgali, Intezar Mehdi, T.L. Suma, Smitha Shekar   +3 more
doaj   +1 more source

Hormonal Therapy Before Micro‐TESE in Men With Nonobstructive Azoospermia: A Negative Answer to an Overly Broad Question

Andrology, EarlyView.
Sandro C. Esteves, Arnold P. P. Achermann, Ricardo Miyaoka, Cassio L. Z. Riccetto, Adriano Fregonesi   +4 more
wiley   +1 more source