Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell +12 more
wiley +1 more source
The value of cardiac magnetic resonance delayed enhancement combined with tissue tracking in discriminating cardiac amyloidosis from hypertrophic cardiomyopathy. [PDF]
Xue XG, Xu XY, Lin XY, Wang GY, Dong HB.
europepmc +1 more source
Evaluating Allocations of Opportunities
ABSTRACT This paper provides a robust criterion for comparing lists of probability distributions—interpreted as allocations of opportunities—faced by different social groups. We axiomatically argue in favor of comparing those lists of probability distributions on the basis of a uniform—among groups—valuation of their expected utility.
Francesco Andreoli +3 more
wiley +1 more source
T-Cell-Driven Immunopathology and Fibrotic Remodeling in Hypertrophic Cardiomyopathy: A Translational Scoping Review. [PDF]
Menezes Junior ADS +4 more
europepmc +1 more source
ABSTRACT Cannabinoids, particularly Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have gained popularity as alternative sleep aids; however, their effects on sleep architecture and next‐day function remain poorly understood. Here, in a pilot trial, we examined the effects of a single oral dose containing 10 mg THC and 200 mg CBD (THC/CBD) on ...
Anastasia Suraev +17 more
wiley +1 more source
Glyco-Architectural Remodelling of the Feline Heart: Age- and HCM-Related Insights from Lectin Histochemistry. [PDF]
Constantin I +6 more
europepmc +1 more source
Kidney disease impairs tendon function in rats
Abstract figure legend This study demonstrates for the first time that tendon strength is reduced in a rodent model of chronic kidney disease (8 weeks of 0.25% adenine feeding) and confirms concurrent dysfunction in muscle and bone. These findings provide novel characterization of multiple tissues, paving the way for future investigations into the ...
Christopher M. T. Hayden +9 more
wiley +1 more source
Systolic and diastolic blood pressure, abdominal obesity, and alcohol consumption contribute to the risk of hypertrophic and dilated cardiomyopathies in European and East Asian populations. [PDF]
Zhang W +11 more
europepmc +1 more source
Rationale, Objectives and Study Design of the Taiwan Registry of Hypertrophic Cardiomyopathy (THIC). [PDF]
Wu YW +15 more
europepmc +1 more source
Comparison of Diastolic Function Parameters After Alcohol Septal Ablation and Mavacamten Therapy in Obstructive Hypertrophic Cardiomyopathy. [PDF]
Saleh D +15 more
europepmc +1 more source

