Results 101 to 110 of about 46,134 (291)

HCMV miRNA Targets Reveal Important Cellular Pathways for Viral Replication, Latency, and Reactivation

open access: yesNon-Coding RNA, 2018
It is now well appreciated that microRNAs (miRNAs) play a critical role in the lifecycles of many herpes viruses. The human cytomegalovirus (HCMV) replication cycle varies significantly depending on the cell type infected, with lytic replication ...
Nicole L. Diggins, Meaghan H. Hancock
semanticscholar   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte   +2 more
wiley   +1 more source

NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence

open access: yesJournal of Immunology Research, 2016
Objective. Measuring NKG2C+CD57+ natural killer (NK) cell expansion to investigate NK responses against human cytomegalovirus (HCMV) and assessing relationships with adaptive immunity against HCMV. Methods.
John Heath   +5 more
doaj   +1 more source

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)-Seropositive Individuals Are Sites of HCMV Reactivation In Vivo. [PDF]

open access: yes, 2015
Human cytomegalovirus (HCMV) causes significant morbidity in the immunocompromised host. Following primary infection, the virus establishes latent infection in progenitor cells of the myeloid lineage.

core   +1 more source

MORC3, a component of PML nuclear bodies, has a role in restricting herpes simplex virus type 1 and human cytomegalovirus [PDF]

open access: yes, 2016
We previously reported that MORC3, a protein associated with promyelocytic leukemia nuclear bodies (PML NBs), is a target of HSV-1 ICP0 mediated degradation.
Everett, Roger   +2 more
core   +1 more source

Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome

open access: yesVirology Journal, 2017
AIM2, a cytosolic DNA sensor, plays an important role during infection caused by pathogens with double-stranded DNA; however, its role in human cytomegalovirus (HCMV) infection remains unclear.
Yuan-Chung Huang   +7 more
semanticscholar   +1 more source

Zirconia, titanium, and polyetheretherketone implant abutments show equal long‐term clinical success—A systematic review and network meta‐analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Hundreds of millions of people have one or more missing teeth. Consequently, a substantial number of patients undergo implant therapy each year. However, technical complications and soft tissue inflammation associated with the implant abutment or the type of restoration can lead to bone loss and, ultimately, implant failure.
Yasir Nabeel Al‐Mohammad   +13 more
wiley   +1 more source

Lymphoproliferative Response in Primary Human Cytomegalovirus (HCMV) Infection Is Delayed in HCMV Transmitter Mothers [PDF]

open access: yesThe Journal of Infectious Diseases, 2006
The T cell-mediated immune response to human cytomegalovirus (HCMV) after primary infection, as well as the determinants of intrauterine transmission, are poorly understood.Sequential peripheral blood leukocyte samples from 74 pregnant women and 29 nonpregnant individuals with primary infection were examined for HCMV-specific CD4+ T cells by cytokine ...
Maria Grazia, Revello   +6 more
openaire   +2 more sources

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

open access: yes, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark   +5 more
core   +1 more source

Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways

open access: yesCell Death and Disease, 2017
Cancer is a multifactorial disease and virus-mediated carcinogenesis is one of the crucial factors, which is poorly understood. Human cytomegalovirus (HCMV) is a herpesvirus and its components have been evidenced to be associated with cancer of different
P. Kumari   +7 more
semanticscholar   +1 more source

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