Results 101 to 110 of about 33,214 (206)

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection

The Journal of Clinical Investigation, 2022
Human cytomegalovirus (HCMV) is the most common congenital infection and a leading cause of stillbirth, neurodevelopmental impairment, and pediatric hearing loss worldwide.
Eleanor C. Semmes, Itzayana G. Miller, Courtney E. Wimberly, Caroline T. Phan, Jennifer A. Jenks, Melissa J. Harnois, Stella J. Berendam, Helen Webster, Jillian H. Hurst, Joanne Kurtzberg, Genevieve G. Fouda, Kyle M. Walsh, Sallie R. Permar   +12 more
doaj   +1 more source

Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]

, 2008
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core   +3 more sources

The Story of Human Cytomegalovirus and Cancer: Increasing Evidence and Open Questions

Neoplasia: An International Journal for Oncology Research, 2009
Although human cytomegalovirus (HCMV) is generally not regarded to be an oncogenic virus, HCMV infection has been implicated in malignant diseases from different cancer entities.
Martin Michaelis, Hans W. Doerr, Jindrich Cinatl, Jr   +2 more
doaj   +1 more source

Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes [PDF]

, 2017
Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity.
Adrian J. Giovannone, Alberto Fraile-Ramos, Alenquer M, Barbieri MA, Bezprozvanny I, Bilodeau PS, Breuza L, Britt WJ, Calistri A, Campeau E, Castle AM, Cepeda V, Cepeda V, Chin LS, Clague MJ, Danielsen JM, Delgrossi MH, Dragovic RA, Elena Reales, Fowler KB, Fraile-Ramos A, Fraile-Ramos A, Fujita H, Geng L, Gong Q, Gonzales PA, Guo X, Guo Z, Hackam DJ, Henne WM, Hibi T, Hicke L, Hislop JN, Hong W, Huang F, Huang S, Hurley JH, Jahn R, Kamsteeg EJ, Keith E. Mostov, Kim W, Kwon SH, Kyuuma M, Lakkaraju A, Leung YM, Li X, Liu ST, Low SH, Marchese A, McCullough J, McSharry BP, Meckes DG, Moffat J, Mori Y, Na CH, Naldini L, Naren AP, Olkkonen VM, Ostrowski M, Pallavi Bhattaram, Pawliczek T, Raiborg C, Raiborg C, Ren J, Riento K, Rodriguez-Boulan E, Rothman JE, Sharma N, Shields SB, Shih SC, Simons M, Singer-Lahat D, Somsel Rodman J, Stringer DK, Sudhof TC, Tandon R, ter Beest MB, Thery C, Thomas Weimbs, van Niel G, Weimbs T, Weimbs T, Weimbs T, Wickner W, Wojcikiewicz RJ, Yatsu A, Zerial M   +86 more
core   +3 more sources

Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences. [PDF]

, 2017
External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA.
Li, Wei, LIU, Fenyong, Liu, Yujun, Lu, Sangwei, Sheng, Jingxue, Sun, Xu, Trang, Phong, Vu, Gia-Phong, Xu, Mengqiong, Yang, Zhu   +9 more
core   +2 more sources

Human Cytomegalovirus (HCMV) – Revised [PDF]

Transfusion Medicine and Hemotherapy, 2010
Schottstedt, Volkmar, Blümel, Johannes, Burger, Reinhard, Drosten, Christian, Gröner, Albrecht, Gürtler, Lutz G., Heiden, Margarethe, Hildebrandt, Martin, Jansen, Bernd, Montag-Lessing, Thomas, Offergeld, Ruth, Pauli, Georg, Seitz, Rainer, Schlenkrich, Uwe, Strobel, Johanna, Willkommen, Hannelore, Wirsing von König, Carl-Heinz   +16 more
openaire   +3 more sources

A Novel Link between Stress and Human Cytomegalovirus (HCMV) Infection: Sympathetic Hyperactivity Stimulates HCMV Activation

Virology, 2000
Recently, inflammatory mediators such as TNFalpha were identified as triggering active human cytomegalovirus (HCMV) infection. Here, we demonstrate that a highly stressful event in the absence of systemic inflammation, as observed in patients with acute myocardial infarction, leads to the development of an active HCMV infection in latently infected ...
Prösch, Susanna, Wendt, Cornelia E.C., Reinke, Petra, Priemer, Christina, Oppert, Michael, Krüger, Detlev H., Volk, Hans-Dieter, Döcke, Wolf-Dietrich   +7 more
openaire   +2 more sources

Serological Evidence and Sociodemographic Risk Factors of Recent Cytomegalovirus Infection in Pregnant Women Attending a Tertiary Hospital in Maiduguri, Nigeria

Journal of Medical Microbiology and Infectious Diseases, 2014
Introduction : Human cytomegalovirus (HCMV) is able to go into latency and is the most common cause of congenital infections in humans. Its clinical manifestations range from asymptomatic forms to severe fetal damage, and in rare cases, fetal death due ...
Adamu Babayo, Thairu Yunusa, Idris Abdullahi Nasir, Marycelin B. Baba   +3 more
doaj  

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

mBio, 2016
Infection with human cytomegalovirus (HCMV) profoundly affects cellular metabolism. Like in tumor cells, HCMV infection increases glycolysis, and glucose carbon is shifted from the mitochondrial tricarboxylic acid cycle to the biosynthesis of fatty acids.
S. Karniely, M. P. Weekes, R. Antrobus, J. Rorbach, L. van Haute, Y. Umrania, D. L. Smith, R. J. Stanton, M. Minczuk, P. J. Lehner, J. H. Sinclair   +10 more
doaj   +1 more source