Results 111 to 120 of about 46,134 (291)
European Journal of Immunology, Volume 56, Issue 2, February 2026.Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Pediatrics and Neonatology, 2020 Background: Human cytomegalovirus (HCMV) is a common pathogen that causes many diseases in young children. HCMV glycoprotein H (gH) genotypes may be associated with the type and severity of some diseases.
Wei Li +5 more
doaj +1 more source
Journal of Cardiothoracic Surgery, 2023 Background Aortic dissection (AD) is a rare disease with high mortality for which no effective diagnostic biomarkers are available. Human cytomegalovirus (HCMV) infection is an important cause of the occurrence and progression of many diseases, but the ...
Yongqing Cheng +8 more
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Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity [PDF]
, 2012 A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling.
Balzarini, Jan +4 more
core +1 more source
Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions
Aging Cell, Volume 25, Issue 2, February 2026.Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki +3 more
wiley +1 more source
Cytomegalovirus in urinary sediment in patients with acute kidney injury
BMC Nephrology, 2021 Background Immunosuppression in solid organ transplantation is associated with frequent infections. Renal allograft recipients are susceptible to opportunistic infections and can acquire human cytomegalovirus (HCMV) infections even within the allograft ...
Sahra Pajenda +9 more
doaj +1 more source
Species-Specific Inhibition of Necroptosis by HCMV UL36 [PDF]
, 2021 Elena Muscolino +4 more
openalex +1 more source
Development of novel vaccines against human cytomegalovirus
Human Vaccines & Immunotherapeutics, 2019 Congenital human cytomegalovirus (HCMV) infection and HCMV infection of the immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. Efforts to develop HCMV vaccines have
Xinle Cui, Clifford M. Snapper
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Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells
Biotechnology and Bioengineering, Volume 123, Issue 1, Page 196-211, January 2026.In this study, the authors identified regions with enhancer activity in the CHO cell genome using genome‐wide and targeted STARR‐seq. The analysis revealed thousands of newly identified enhancer sequences, where some of the most active sequences could drive transgene expression at levels similar to or higher than strong viral enhancers.
María Santos +9 more
wiley +1 more source
The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts
Viruses, 2018 Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus for which there is no vaccine or cure. This viral infection, once acquired, is life-long, residing latently in hematopoietic cells.
M. Nukui, C. O’Connor, Eain A. Murphy
semanticscholar +1 more source