Results 111 to 120 of about 33,214 (206)

Immune reconstitution of human cytomegalovirus-specific T lymphocytes after allogeneic hematopoietic stem cell transplantation and their predictive role in reactivation

Frontiers in Immunology
Human cytomegalovirus (HCMV) is the most common virus to affect the recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT). HCMV reactivation increases the risk of secondary fungal and bacterial infections, as well as that of non ...
Yuanqi Zhao, Yuanqi Zhao, Yuanqi Zhao, Sisi Zhen, Sisi Zhen, Jiali Wang, Jiali Wang, Jieru Wang, Jieru Wang, Runzhi Ma, Runzhi Ma, Li Liu, Li Liu, Aiming Pang, Aiming Pang, Rongli Zhang, Rongli Zhang, Xin Chen, Xin Chen, Weihua Zhai, Weihua Zhai, Donglin Yang, Donglin Yang, Yi He, Yi He, Mingzhe Han, Mingzhe Han, Erlie Jiang, Erlie Jiang, Sizhou Feng, Sizhou Feng   +30 more
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Is the presence of HCMV components in CNS tumors a glioma-specific phenomenon?

Virology Journal, 2019
Background Human cytomegalovirus (HCMV) has been associated with malignant gliomas. The purpose of the present study was to investigate the presence of HCMV in common non-glial tumors of the central nervous system (CNS) and to determine whether it is a ...
Daling Ding, Ailing Zhao, Zhi Sun, Lihua Zuo, Anhua Wu, Jianrui Sun   +5 more
doaj   +1 more source

Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]

, 1990
Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Pavic, Ivica, Rukavina, Daniel   +4 more
core  

Human cytomegalovirus: taking the strain [PDF]

, 2015
In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV), we reflect on the merits and limitations of the viral strains currently being used to develop urgently needed treatments.
Aicheler, Rebecca, Davison, Andrew J., Fielding, Ceri A., Lehner, Paul J., Murrell, Isa, Seirafian, Sepher, Stanton, Richard J., Tomasec, Peter, Wang, Edward C. Y., Weekes, Michael, Wilkie, Gavin, Wilkinson, Gavin W. G.   +11 more
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Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients

Journal of Translational Medicine, 2017
Background Oral lichen planus (OLP) is a T cell-mediated autoimmune disease. The aetiology and molecular mechanisms of OLP remain unclear. Human cytomegalovirus (HCMV) infection is a causal factor in the development of various diseases, but the clinical ...
Meng Ding, Xiang Wang, Cheng Wang, Xiaoshuang Liu, Ke Zen, Wenmei Wang, Chen-Yu Zhang, Chunni Zhang   +7 more
doaj   +1 more source

Human Cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against NK cell cytotoxicity. [PDF]

, 2003
The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I-related ligands, including the MIC and ULBP proteins.
Chalupny, NJ, Cosman, D, Dosch, S, Dunn, C, Johnson, DC, Sivakumar, PV, Sutherland, CL   +6 more
core  

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Natural killer cells as an initial defense against pathogens. [PDF]

, 2006
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse range of pathogens. Recognition of infection by NK cells is accomplished by the activation of receptors on the NK cell surface, which initiate NK cell ...
Lanier, Lewis L, Lodoen, Melissa B
core  

Effect of host telomerase inhibition on human cytomegalovirus

Journal of Virology
Treatment options remain limited for human cytomegalovirus (HCMV). Host telomerase has been implicated in the pathogenesis and oncogenesis of multiple herpesviruses, most recently including HCMV.
Chloe M. Cavanaugh, Cora N. Betsinger, Nicole Katchur, Sherry Zhang, Karen Yang, Maciej Nogalski, Ileana M. Cristea, Daniel Notterman   +7 more
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尸体肾移植术后活动性 HCMV 感染的预防性治疗

Zhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 探讨尸体肾移植术后人巨细胞病毒(HCMV)病的防治。方法: 应用 HCMV-Ag 试验诊断 HCMV 感染。对本 院实施的 1 150例尸体肾移植分两组进行回顾性分析。结果: 治疗组: 1989年 9 月～ 1997年 4 月共 1 050 例,HCMV 病 45 例,治 愈 30例, 死亡 15例; 预防组: 1997 年 5 月～ 1998 年 5 月,共 100 例,HCMV 感染 42例, 由于进行了预防性治疗,无 1例 HCMV 病 发生和因 HCMV 感染而死亡。结论: HCMV ...
郑克立　吴培根　朱兰英　洪良庆　刘　东
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