Interstrain recombinants of human cytomegalovirus uncouple glycoprotein display, virion infectivity, and spread characteristics. [PDF]
Peterson CS +4 more
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Repurposing of the bisbenzimide antibiotic Ridinilazole as an antiviral compound against human cytomegalovirus. [PDF]
Pinto H +4 more
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Optimizing delivery of an anti-cytomegalovirus inhibitory peptide using a cell-penetrating peptide. [PDF]
Beeton K +4 more
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Cross-herpesvirus immunity of the cytomegalovirus gB/MF59 vaccine response. [PDF]
Lankina A +9 more
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Retraction: The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection. [PDF]
PLOS Pathogens Editors.
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Human cytomegalovirus (HCMV) shedding has been extensively investigated in newborns and in young children, however, much less is known about it in immunocompetent adults. Shedding of HCMV was investigated in saliva, vaginal secretions and urine of pregnant women experiencing primary infection along with the development of the HCMV-specific immune ...
C. Fornara +8 more
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Models of HCMV latency and reactivation
Trends in Microbiology, 2003Human cytomegalovirus (HCMV) is a ubiquitous β-herpesvirus that causes severe disease primarily in immunosuppressed individuals. A major characteristic of HCMV, with obvious clinical importance, is its ability to establish lifelong infection within the host following the initial acute infection.
Daniel N, Streblow, Jay A, Nelson
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Adoptive immunotherapy of HCMV infection
Cytotherapy, 2007Human cytomegalovirus (HCMV) infection or reactivation is a frequent cause of morbidity and mortality in immunocompromised individuals such as transplant recipients. Primary HCMV infection or reactivation of HCMV from latency is mostly asymptomatic in immunocompetent individuals and is controlled by the host's cell-mediated immune response.
M, Kapp +3 more
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The study of strategies for the treatment of human cytomegalovirus (HCMV) infection starts with the discovery of compounds that are potent and selective inhibitors of HCMV replication. Selectivity means that the window between the concentrations that block viral replication on the one hand and those that affect host cell functions on the other is ...
J, Neyts +4 more
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