Results 141 to 150 of about 31,967 (178)

Specificity for HCMV strains

Nature Reviews Immunology, 2018
Strain-specific recognition of different UL40 peptides determines the proliferation and activation of NKG2C+ NK cells during HCMV infection.
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Role of human cytomegalovirus (HCMV)-specific antibody in HCMV-infected pregnant women

Early Human Development, 2014
Maternal preconception immunity confers substantial protection against HCMV infection and disease to the unborn child. However, the protective role played by single components of virus-specific humoral and cellular immunity is poorly defined. Recently, it was discovered that UL128-131 gene products are essential for the virus to exert endothelial ...
Maria Grazia, Revello, Chiara, Fornara, Alessia, Arossa, Paola, Zelini, Daniele, Lilleri   +4 more
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Human cytomegalovirus (HCMV) genotype populations in immunocompetent individuals during primary HCMV infection

Journal of Clinical Virology, 2010
Immunocompetent individuals can harbor multiple human cytomegalovirus (HCMV) genotypes. However, little is known about the genotype populations acquired during primary HCMV infection.The aim of this study was to assess the HCMV genotype populations present in the blood of non-immunocompromised patients experiencing primary HCMV infection.HCMV ...
Irene, Görzer, Heidrun, Kerschner, Monika, Redlberger-Fritz, Elisabeth, Puchhammer-Stöckl   +3 more
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HCMV microinfections in inflammatory diseases and cancer

Journal of Clinical Virology, 2008
Human cytomegalovirus (HCMV) is a wide-spread human virus that was mainly known to cause disease in immunocompromised patients. A new entity of infection can be diagnosed with high sensitive techniques; HCMV microinfections that often exhibit an altered pattern of IE protein expression.
Cecilia Soderberg-Naucler
exaly   +3 more sources

Diagnosis and prognostic markers of HCMV infection

Journal of Clinical Virology, 2001
Human cytomegalovirus (HCMV) infections are frequently observed as well in immunocompetent as in immunocompromised patients. Diagnostic techniques for HCMV detection have greatly improved during the recent years. Detection of HCMV by culture has been bettered by centrifugating samples in a shell vial and by using monoclonal antibody to the immediate ...
L, Grangeot-Keros, D, Cointe
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Challenges and advances in the management of HCMV infections

Virologie
Human cytomegalovirus (HCMV) is one of the most important causes of complications in immunocompromised patients and congenital infections. HCMV could also represent an interesting target for treatment to limit the progression of glioblastoma, a highly aggressive tumor. Ganciclovir, foscarnet and cidofovir, which interfere with the activity of the viral
Gourin, Claire, Flores, Thelma, Mafi, Sarah, Malnou, Cécile, Alain, Sophie, Hantz, Sébastien, Ligat, Gaetan   +6 more
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Dendritic Cells and HCMV Cross-Presentation

2003
The outcome of a viral infection is the result of an endless fight between the organism whose task is to mount an antiviral response and the virus that adapts strategies to circumvent the host response. Human cytomegalovirus (HCMV), a latent herpesvirus, can be considered as a spearhead in exploiting co-existence with the host to develop numerous ...
G, Arrode, C, Davrinche
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Entry route of HCMV into endothelial cells

Journal of Clinical Virology, 2008
Human cytomegalovirus (HCMV) is generally assumed to enter its target cells by direct fusion at the plasma membrane while sequestration and lysis of viral particles within endocytic vesicles has been suggested as an abortive entry pathway of fibroblast-adapted HCMV strains in endothelial cells.
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Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry

Cell, 2021
Marc Kschonsak, Lionel Rouge, Christopher P Arthur   +2 more
exaly  

Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer

Immunity, 2023
Dagmar Stöhr, Hanna Janicki, Florian Klein   +2 more
exaly