Results 181 to 190 of about 33,214 (206)

Does human cytomegalovirus provide a novel therapeutic target for patients with glioblastoma? [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci
Söderberg-Naucler C   +3 more
europepmc   +1 more source

Human cytomegalovirus (HCMV) long-term shedding and HCMV-specific immune response in pregnant women with primary HCMV infection

Medical Microbiology and Immunology, 2022
Human cytomegalovirus (HCMV) shedding has been extensively investigated in newborns and in young children, however, much less is known about it in immunocompetent adults. Shedding of HCMV was investigated in saliva, vaginal secretions and urine of pregnant women experiencing primary infection along with the development of the HCMV-specific immune ...
C. Fornara   +8 more
openaire   +3 more sources

Adoptive immunotherapy of HCMV infection

Cytotherapy, 2007
Human cytomegalovirus (HCMV) infection or reactivation is a frequent cause of morbidity and mortality in immunocompromised individuals such as transplant recipients. Primary HCMV infection or reactivation of HCMV from latency is mostly asymptomatic in immunocompetent individuals and is controlled by the host's cell-mediated immune response.
M, Kapp   +3 more
openaire   +2 more sources

Human cytomegalovirus (HCMV) genotype populations in immunocompetent individuals during primary HCMV infection

Journal of Clinical Virology, 2010
Immunocompetent individuals can harbor multiple human cytomegalovirus (HCMV) genotypes. However, little is known about the genotype populations acquired during primary HCMV infection.The aim of this study was to assess the HCMV genotype populations present in the blood of non-immunocompromised patients experiencing primary HCMV infection.HCMV ...
Irene, Görzer   +3 more
openaire   +2 more sources

Specificity for HCMV strains

Nature Reviews Immunology, 2018
Strain-specific recognition of different UL40 peptides determines the proliferation and activation of NKG2C+ NK cells during HCMV infection.
openaire   +2 more sources

Role of human cytomegalovirus (HCMV)-specific antibody in HCMV-infected pregnant women

Early Human Development, 2014
Maternal preconception immunity confers substantial protection against HCMV infection and disease to the unborn child. However, the protective role played by single components of virus-specific humoral and cellular immunity is poorly defined. Recently, it was discovered that UL128-131 gene products are essential for the virus to exert endothelial ...
Maria Grazia, Revello   +4 more
openaire   +2 more sources

Methods in Anti-HCMV Research

2003
The study of strategies for the treatment of human cytomegalovirus (HCMV) infection starts with the discovery of compounds that are potent and selective inhibitors of HCMV replication. Selectivity means that the window between the concentrations that block viral replication on the one hand and those that affect host cell functions on the other is ...
J, Neyts   +4 more
openaire   +2 more sources

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