Results 281 to 290 of about 44,631 (298)
Some of the next articles are maybe not open access.
Medical Microbiology and Immunology, 2022
Human cytomegalovirus (HCMV) shedding has been extensively investigated in newborns and in young children, however, much less is known about it in immunocompetent adults. Shedding of HCMV was investigated in saliva, vaginal secretions and urine of pregnant women experiencing primary infection along with the development of the HCMV-specific immune ...
C. Fornara +8 more
openaire +3 more sources
Human cytomegalovirus (HCMV) shedding has been extensively investigated in newborns and in young children, however, much less is known about it in immunocompetent adults. Shedding of HCMV was investigated in saliva, vaginal secretions and urine of pregnant women experiencing primary infection along with the development of the HCMV-specific immune ...
C. Fornara +8 more
openaire +3 more sources
Nature Reviews Immunology, 2018
Strain-specific recognition of different UL40 peptides determines the proliferation and activation of NKG2C+ NK cells during HCMV infection.
openaire +3 more sources
Strain-specific recognition of different UL40 peptides determines the proliferation and activation of NKG2C+ NK cells during HCMV infection.
openaire +3 more sources
Nature Reviews Microbiology, 2011
A new paper reveals that HCMV can escape a neutralizing antibody by incorporating it into assembling virions.
openaire +3 more sources
A new paper reveals that HCMV can escape a neutralizing antibody by incorporating it into assembling virions.
openaire +3 more sources
2003
The study of strategies for the treatment of human cytomegalovirus (HCMV) infection starts with the discovery of compounds that are potent and selective inhibitors of HCMV replication. Selectivity means that the window between the concentrations that block viral replication on the one hand and those that affect host cell functions on the other is ...
Erik De Clercq +4 more
openaire +3 more sources
The study of strategies for the treatment of human cytomegalovirus (HCMV) infection starts with the discovery of compounds that are potent and selective inhibitors of HCMV replication. Selectivity means that the window between the concentrations that block viral replication on the one hand and those that affect host cell functions on the other is ...
Erik De Clercq +4 more
openaire +3 more sources
Nature Reviews Microbiology, 2011 Tetherin (also known as BST2) is known to inhibit the release of numerous enveloped viruses. Surprisingly, this study shows that, in the case of human cytomegalovirus (HCMV), tetherin has a beneficial role for the virus, enhancing its entry into the host cell. Cells induced to stably express tetherin showed higher HCMV infection levels than controls in
openaire +1 more source
Journal of Clinical Virology, 2010
Immunocompetent individuals can harbor multiple human cytomegalovirus (HCMV) genotypes. However, little is known about the genotype populations acquired during primary HCMV infection.The aim of this study was to assess the HCMV genotype populations present in the blood of non-immunocompromised patients experiencing primary HCMV infection.HCMV ...
Irene Görzer +3 more
openaire +3 more sources
Immunocompetent individuals can harbor multiple human cytomegalovirus (HCMV) genotypes. However, little is known about the genotype populations acquired during primary HCMV infection.The aim of this study was to assess the HCMV genotype populations present in the blood of non-immunocompromised patients experiencing primary HCMV infection.HCMV ...
Irene Görzer +3 more
openaire +3 more sources
Models of HCMV latency and reactivation
Trends in Microbiology, 2003Human cytomegalovirus (HCMV) is a ubiquitous β-herpesvirus that causes severe disease primarily in immunosuppressed individuals. A major characteristic of HCMV, with obvious clinical importance, is its ability to establish lifelong infection within the host following the initial acute infection.
Daniel N. Streblow, Jay A. Nelson
openaire +3 more sources
Role of human cytomegalovirus (HCMV)-specific antibody in HCMV-infected pregnant women
Early Human Development, 2014Maternal preconception immunity confers substantial protection against HCMV infection and disease to the unborn child. However, the protective role played by single components of virus-specific humoral and cellular immunity is poorly defined. Recently, it was discovered that UL128-131 gene products are essential for the virus to exert endothelial ...
Paola Zelini +4 more
openaire +3 more sources
Diagnosis and prognostic markers of HCMV infection
Journal of Clinical Virology, 2001Human cytomegalovirus (HCMV) infections are frequently observed as well in immunocompetent as in immunocompromised patients. Diagnostic techniques for HCMV detection have greatly improved during the recent years. Detection of HCMV by culture has been bettered by centrifugating samples in a shell vial and by using monoclonal antibody to the immediate ...
Denis Cointe, Liliane Grangeot-Keros
openaire +3 more sources
Journal of Clinical Virology, 2003
Human cytomegalovirus (HCMV) reactivation may cause severe disease in immunosuppressed patients. Quantitation of HCMV viral load in the blood has been shown to be important in predicting for HCMV disease, however the particular blood compartment that should be tested, plasma versus peripheral blood leukocytes (PBL), has been subject to debate.To ...
Denis Spelman +4 more
openaire +3 more sources
Human cytomegalovirus (HCMV) reactivation may cause severe disease in immunosuppressed patients. Quantitation of HCMV viral load in the blood has been shown to be important in predicting for HCMV disease, however the particular blood compartment that should be tested, plasma versus peripheral blood leukocytes (PBL), has been subject to debate.To ...
Denis Spelman +4 more
openaire +3 more sources