Results 81 to 90 of about 33,214 (206)

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

open access: yesInterdisciplinary Medicine, Volume 4, Issue 2, March 2026.
In normal pregnancy, PEVs help maintain maternal–fetal immune tolerance while enabling controlled immune activation, promote endothelial migration, and support trophoblast invasion and syncytialization, strengthening antimicrobial defense. In pregnancy‐related disorders, dysregulated PEV signaling may drive endothelial dysfunction and hypertension, BBB
Jiale Du   +5 more
wiley   +1 more source

Development of novel vaccines against human cytomegalovirus

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Congenital human cytomegalovirus (HCMV) infection and HCMV infection of the immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. Efforts to develop HCMV vaccines have
Xinle Cui, Clifford M. Snapper
doaj   +1 more source

Epidemiological characteristics of human cytomegalovirus infection and glycoprotein H genotype in Chinese children

open access: yesPediatrics and Neonatology, 2020
Background: Human cytomegalovirus (HCMV) is a common pathogen that causes many diseases in young children. HCMV glycoprotein H (gH) genotypes may be associated with the type and severity of some diseases.
Wei Li   +5 more
doaj   +1 more source

Human cytomegalovirus Fcγ binding proteins gp34 and gp68 antagonize Fcγ receptors I, II and III. [PDF]

open access: yesPLoS Pathogens, 2014
Human cytomegalovirus (HCMV) establishes lifelong infection with recurrent episodes of virus production and shedding despite the presence of adaptive immunological memory responses including HCMV immune immunoglobulin G (IgG).
Eugenia Corrales-Aguilar   +11 more
doaj   +1 more source

Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]

open access: yes, 2016
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core   +1 more source

Primary Human Cytomegalovirus (HCMV) Infection in Pregnancy [PDF]

open access: yesDeutsches Ärzteblatt international, 2017
In 0.5-4% of pregnancies, the prospective mother sustains a primary infection with human cytomegalovirus (HCMV). An HCMV infection of the fetus in the first or second trimester can cause complex post-encephalitic impairment of the infant brain, leading to motor and mental retardation, cerebral palsy, epilepsy, retinal defects, and progressive hearing ...
Horst, Buxmann   +3 more
openaire   +2 more sources

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 1, Page 26-46, March 2026.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan   +3 more
wiley   +1 more source

Cytomegalovirus in urinary sediment in patients with acute kidney injury

open access: yesBMC Nephrology, 2021
Background Immunosuppression in solid organ transplantation is associated with frequent infections. Renal allograft recipients are susceptible to opportunistic infections and can acquire human cytomegalovirus (HCMV) infections even within the allograft ...
Sahra Pajenda   +9 more
doaj   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng   +8 more
wiley   +1 more source

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells

open access: yesFrontiers in Immunology, 2017
Human cytomegalovirus (HCMV) primary infection and periodic reactivation of latent virus is generally well controlled by T-cell responses in healthy people.
Sarah E. Jackson   +5 more
doaj   +1 more source

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