Results 101 to 110 of about 52,371 (292)

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Hybrid modeling for optimizing cell cultivation in mAb production using a small‐scale automated experimental platform

AIChE Journal, EarlyView.
Abstract This work presents the optimization of cell cultivation for monoclonal antibody (mAb) production. We developed a hybrid model describing the effects of multiple process variables on antibody productivity and impurity generation. An automated platform with 12 × 250 mL bioreactors was set up.
Kosuke Nemoto, Yuki Yoshiyama, Mizuki Morisasa, Junshin Iwabuchi, Yusuke Hayashi, Sara Badr, Hirokazu Sugiyama   +6 more
wiley   +1 more source

Knowledge and attitudes of tuberculosis management in San Juan de Lurigancho district of Lima, Peru

Journal of Infection in Developing Countries, 2009
Background: Expansion of the health care workforce in Peru to combat tuberculosis (TB) includes both professional health care providers (HCPs) such as doctors and nurses, and non-professional HCPs such as community health workers (CHWs). We describe the
Elizabeth M. Kiefer, Theresa Shao, Olveen Carrasquillo, Pamela Nabeta, Carlos Seas   +4 more
doaj   +1 more source

Band Structures of Symmetrical Graphene Superlattice with Cells of three Regions

, 2017
We study the electronic band structures of massless Dirac fermions in symmetrical graphene superlattice with cells of three regions. Using the transfer matrix method, we explicitly determine the dispersion relation in terms of different physical ...
Choubabi, El Bouâzzaoui, Jellal, Ahmed, Kamal, Abdellatif   +2 more
core   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, EarlyView.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source

Characterization of host cell proteins in the downstream process of plant-Based biologics using LC-MS profiling

Biotechnology Reports
Host cell proteins (HCPs) are process-related impurities found in biopharmaceutical products that can impair their safety and efficacy. While ELISA has traditionally been employed to quantify HCPs, LC-MS emerges as a powerful alternative for precise ...
Chalisa Panapitakkul, Christine Joy I. Bulaon, Nuttapat Pisuttinusart, Waranyoo Phoolcharoen   +3 more
doaj   +1 more source

Healthcare professionals’ perceptions on the emotional impact of having an inadequate response to antidepressant medications: survey and prospective patient audit

Annals of General Psychiatry, 2018
Background Despite the availability of effective antidepressants, about half of patients with major depressive disorder (MDD) display an inadequate response to their initial treatment.
Rajnish Mago, Andrea Fagiolini, Emmanuelle Weiller, Catherine Weiss   +3 more
doaj   +1 more source

Translating Research to Practice for Children With Autism Spectrum Disorder: Part 2: Behavior Management in Home and Health Care Settings [PDF]

, 2016
Introduction Managing home and health care for children with autism spectrum disorder can be challenging because of the range of symptoms and behaviors exhibited. Method This article presents an overview of the emerging science related to the methods to
Bultas, Margaret W., Burkett, Karen, Johnson, Norah L., PhD, RN, CPNP, Reinhold, Judy   +3 more
core   +1 more source

Staff Nurse Ratings of Implementation Self-Efficacy for EBP (ISE4EBP) and Organizational EBP Readiness [PDF]

, 2020
There is limited research about nurses' confidence in implementing evidence into clinical practice. The purpose of this study was to further test, refine and strengthen the Implementation Self-Efficacy for EBP (ISE4EBP) scale and gain knowledge about ...
Sobieski, Tessa
core  

ARIA 2016 : Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle [PDF]

, 2016
European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA-France, EU Structural and Development Fund Languedoc-Roussillon, ARIA.Peer reviewedPublisher ...
Agache, I, Bachert, C., Bedbrook, A., Bergmann, K. C., Bousquet, J, Hellings, P. W., Price, D.   +6 more
core   +1 more source