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Dichlorvos-induced toxicity in HCT116 cells: Involvement of oxidative stress and apoptosis
Pesticide Biochemistry and Physiology, 2015Organophosphorous (OP) pesticides are widely used in the agriculture and home. Among those pesticides, Dichlorvos (DDVP) is a worldwide used insecticide for pest control. DDVP is commonly used as an insecticide for maintenance and growth of agricultural products, to control the internal and external parasites of farm animals, and to eradicate insects ...
Intidhar, Ben Salem +3 more
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Significance of Notch and Wnt signaling for chemoresistance of colorectal cancer cells HCT116
Journal of Cellular Biochemistry, 2018Abstract5‐fluorouracil (5‐FU) and oxaliplatin (OxaPt) are the main chemotherapeutics for colorectal cancer (CRC). Chemotherapy response rates for advanced CRC remain low, primarily due to intrinsic or acquired chemoresistance. The importance of Notch and Wnt signaling for carcinogenesis of CRC as well as crosstalk of Notch and Wnt signaling with many ...
Egle Kukcinaviciute +5 more
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Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells
Bioorganic & Medicinal Chemistry, 2012Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drugs. In order to find new drugs with anticancer activities, we combined coumarins with polysulfides in the form of di-coumarin polysulfides. These novel compounds were tested in the HCT116 colorectal cancer cell line.
Nathaniel Edward Bennett Saidu +5 more
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Characteristics of Apoptosis in HCT116 Colon Cancer Cells Induced by Deoxycholic Acid
The Journal of Biochemistry, 2005Hydrophobic bile acids induce apoptosis in both colon cancer cells and hepatocytes. The mechanism by which colon cancer cells respond to bile acids is thought to be different from that of hepatocytes. Therefore, we investigated the characteristics of apoptosis in colon cancer cell line HCT116.
Satoko, Yui +3 more
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Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line
Molecular and Cellular Biochemistry, 2011Dihydroartemisinin (DHA) is an important artemisinin derivative and presents profound anti-tumor potential. A DHA-resistant cell line named HCT116/R derived from colon carcinoma cell line HCT116 was established in our previous study. Herein, we found that HCT116/R cells were much more resistant to DHA- or artesunate-induced proliferation inhibition and
Jin-Jian, Lu +3 more
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Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
Mechanisms of Ageing and Development, 2009Induction of senescence has been proposed as a possible in vivo tumor response to anticancer treatment. Senescent cancer cells are often polyploid, however, their route to polyploidy is poorly recognized (endoreduplication versus aberrant mitoses).
Malgorzata A, Sliwinska +8 more
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Increased PKN2 and M2-Polarized Macrophages Promote HCT116 Cell Invasion
Critical Reviews in ImmunologyColorectal cancer is the third most common malignant tumor, with highly invasive and metastatic potential in the later stage. This study investigated the role of PKN2 overexpression and M2-polarized macrophages in dictating the malignant phenotype of colorectal cancer cells.
Cheng, He +3 more
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Characterization of initiation of DNA replication in HCT116 Ku80+- Cells
2005This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
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Apigenin rich-Limonium duriusculum (de Girard) Kuntze promotes apoptosis in HCT116 cancer cells
Natural Product Research, 2021Ameddah Souad +2 more
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