Results 251 to 260 of about 4,460,555 (293)

Corrigendum to “NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression”

Advanced Science, Volume 13, Issue 51, 14 September 2026.
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Cell shape instability during cytokinesis in tetraploid HCT116 cells

Biochemical and Biophysical Research Communications, 2023
Tetraploidy is a hallmark of broad cancer types, but it remains largely unknown which aspects of cellular processes are influenced by tetraploidization in human cells. Here, we found that tetraploid HCT116 cells manifested severe cell shape instability during cytokinesis, unlike their diploid counterparts.
Takahiro, Yamamoto, Ryota, Uehara
openaire   +2 more sources

DIFFERENTIAL GROWTH INHIBITION AND INDUCTION OF APOPTOSIS BY GOSSYPOL BETWEEN HCT116 AND HCT116/BAX^−/– COLORECTAL CANCER CELLS

Clinical and Experimental Pharmacology and Physiology, 2007
SUMMARY Bax is a very important pro‐apoptosis molecule. HCT116/Bax−/– cells do not express the pro‐apoptosis Bcl‐2 family member, Bax. In the present study, the anticancer effects of gossypol on HCT116 and HCT116/Bax−/– cells were compared in terms of inhibition of cell growth, inhibition of colony formation and induction of apoptosis.
Manchao, Zhang, Hongpeng, Liu, Zhenkun, Tian, Jenny, Huang, Mylene, Remo, Q Quentin, Li   +5 more
openaire   +2 more sources

Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model

Journal of Surgical Research, 2008
Colorectal cancer metastases result in a significant number of cancer related deaths. The molecular mechanisms underlying this complex, multi-step pathway are yet to be completely elucidated. In the absence of any transgenic models of colon cancer metastases, an in vivo model system that fulfills the rate limiting steps of metastasis (local invasion ...
Ashwani, Rajput, Ivan, Dominguez San Martin, Rebecca, Rose, Alexander, Beko, Charles, Levea, Elizabeth, Sharratt, Richard, Mazurchuk, Robert M, Hoffman, Michael G, Brattain, Jing, Wang   +9 more
openaire   +2 more sources

Biphasic Regulation of Cell Death and Survival by Hydrophobic Bile Acids in HCT116 Cells

Nutrition and Cancer, 2009
A secondary bile acid, namely, deoxycholic acid (DCA), has been known to promote colon tumors; on the other hand, it also induces apoptosis in several human colon cancer cell lines. A hydrophobic primary bile acid, namely, chenodeoxycholic acid (CDCA), exhibits a similar property of apoptosis induction; DCA and CDCA also trigger some specific ...
Satoko, Yui, Ryuhei, Kanamoto, Tohru, Saeki   +2 more
openaire   +2 more sources

The involvement of ROS generation on Epoxiconazole-induced toxicity in HCT116 cells

Pesticide Biochemistry and Physiology, 2018
Abstract Triazole fungicides are the most efficient class of pesticides and have been in rapid development since the 1970s, receiving worldwide recognition. Epoxiconazole is a systemic fungicide belonging to the most widely used members of triazole group and its environmental residue in water has been detected at concentrations up to 7.7 g/l [1 ...
Hiba, Hamdi, Intidhar, Ben Salem, Yosra, Ben Othmène, Emna, Annabi, Salwa, Abid-Essefi   +4 more
openaire   +2 more sources

Live cell catapulting and recultivation does not change the karyotype of HCT116 tumor cells

Cancer Genetics and Cytogenetics, 2005
We used laser microdissection and pressure catapulting (LMPC) to isolate and subsequently recultivate cells from the colorectal cancer cell line HCT116. Cell isolation and recultivation was repeated 5 times from the preceding cell culture. The chromosomal composition of the HCT116 cells was analyzed at the beginning and after each recultivation. We did
Sabine, Langer, Jochen B, Geigl, Susanne, Ehnle, Rainer, Gangnus, Michael R, Speicher   +4 more
openaire   +2 more sources

HCT116 cell line heterogeneity: A useful tool for preclinical research

Chemico-Biological Interactions
Cancer cell heterogeneity is one of the reasons for anticancer chemotherapy failure. Nowadays, this field of research is receiving increasing attention, but mainly as a descriptive characteristic of the tumor. In this study, the property of heterogeneity of tumor colonies is considered as the basis for the identification of effective treatment schemes.
Tatyana A. Grigoreva, Aleksandra V. Sagaidak, Daria N. Kindt, Anastasiya D. Zenina, Angelina A. Romanova, Gleb S. Ivanov, Tatyana K. Yakovleva, Viktoriya I. Turilova, Vyacheslav G. Tribulovich   +8 more
openaire   +2 more sources

Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells

Journal of Natural Products, 2018
HCT116 colorectal cancer cell sensitivity to peloruside A (PLA) in normoxia is not altered by hypoxia preconditioning of the cells. We examined whether the PLA effects were altered in hypoxia and whether the activity was dependent on p53. The cytotoxicity of PLA in wild-type HCT116 cells was largely unaffected by hypoxia; however, cells in which p53 ...
Jiří Řehulka, Narendran Annadurai, Ivo Frydrych, Petr Džubák, John H. Miller, Marián Hajdúch, Viswanath Das   +6 more
openaire   +3 more sources

[Suppression of HCT116 growth of cells by Gadd45].

Zhonghua yi xue za zhi, 2004
To study the mechanism of suppression of growth of HCT116 human colon carcinoma cells by Gadd45 gene.HCT116 human colon carcinoma cells were transfected with pTRE-Gadd45 vector so as to establish Gadd45-inducible cell line that was cultured in medium with tetracycline. Then tetracycline was withdrawn. The number of cell clones was counted.
Tong, Tong, Yong-mei, Song, Ming, Fu, Li-jia, Dong, Shun-qian, Jin, Min, Wu, Qi-min, Zhan   +6 more
openaire   +1 more source