Results 231 to 240 of about 4,460,555 (293)

Licochalcone C Inhibits the Growth of Human Colorectal Cancer HCT116 Cells Resistant to Oxaliplatin. [PDF]

Biomol Ther (Seoul)
Lee SO, Joo SH, Lee JY, Kwak AW, Kim KT, Cho SS, Yoon G, Choi YH, Park JW, Shim JH.   +9 more
europepmc   +1 more source

Tryptophan metabolism in colorectal cancer: From mechanistic insights to novel therapeutic strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Tryptophan metabolism modulates CRC via three microbiota‐regulated pathways with distinct dual‐mode effects. The kynurenine pathway provides biomarkers, serotonin pathway supports SSRI‐combined immunotherapy, indole pathway yields immunostimulatory metabolites, collectively offering translational prospects.
Ran Wang, Wenke Shen, Ping Yang, Dongxue Yang, Yuepeng Cao, Yuping Zhou   +5 more
wiley   +1 more source

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

Food Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi, Sally Kamau, Gulnaz Seitimova, Shynar Zhumagaliyeva, Javad Sharifi‐Rad, William N. Setzer, Daniela Calina   +6 more
wiley   +1 more source

Exploring the apoptotic effects of sericin on HCT116 cells through comprehensive nanostring transcriptomics and proteomics analysis. [PDF]

Sci Rep
Ratanabunyong S, Siriwaseree J, Wanaragthai P, Krobthong S, Yingchutrakul Y, Kuaprasert B, Choowongkomon K, Aramwit P.   +7 more
europepmc   +1 more source

DNA Replication Stress‐Induced Transcriptome of Human Burkitt's Lymphoma Identifies Reciprocal Regulation Between MBD1 and BCL6 During Germinal Center‐Derived B‐Lymphomagenesis

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal, Kyoko Oichai, Hongtae Kim, Kyungjae Myung, Jacqueline H. Barlow   +4 more
wiley   +1 more source

Domperidone, a Dopamine Receptor D2 Antagonist, Induces Apoptosis by Inhibiting the ERK/STAT3-Mediated Pathway in Human Colon Cancer HCT116 Cells. [PDF]

Biomol Ther (Seoul)
Sim SJ, Jang JH, Choi JS, Chun KS.
europepmc   +1 more source

Bovine Colostrum‐Derived Extracellular Vesicles Impair Cancer Cell Proliferation Through Transcriptional Dysregulation

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Milk‐derived extracellular vesicles (EVs) are a promising source of molecules with therapeutic potential. Bovine colostrum is particularly enriched in EVs, which carry cargo of proteins involved in immune regulation, development and cellular signalling.
Claudia Betsabé Huesa‐Carballo, Bruno Puga, Susana Bravo, Manuel Rodríguez‐Pérez, Yessica Domínguez‐Novoa, Julio Iglesias‐García, Brígida Hermida, Isolina Raña, María Teresa Antelo, Rafael López‐López, Miguel Abal, Jorge Barbazán   +11 more
wiley   +1 more source

Differential lipid analysis of oxaliplatin-sensitive and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation. [PDF]

Anal Bioanal Chem
Larson TS, DiProspero TJ, Glish GL, Lockett MR.   +3 more
europepmc   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 250-276, September 2026.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

Responsive ZIF-90 nanocomposite material: targeted delivery of 10-hydroxycamptothecine to enhance the therapeutic effect of colon cancer (HCT116) cells. [PDF]

RSC Med Chem
Guo JC, Deng SH, Zhou SM, Zhou X, Du J, Zhou SH, Zhao QH, Cai ZY, Ren X, Xie MJ.   +9 more
europepmc   +1 more source