Results 121 to 130 of about 276,656 (346)

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Seroprevalence of markers of hepatitis C virus exposure and associated factors in adults aged 18-39 years in the Arctic Russian city of Arkhangelsk: a cross-sectional study

International Journal of Circumpolar Health, 2019
Hepatitis C, caused by the hepatitis C virus (HCV), is a major public health issue in Russia. The aim of our study was to assess the seroprevalence of markers of HCV exposure and factors associated with HCV seropositivity among the general population ...
Tatiana Balaeva, Andrej M. Grjibovski, Olga Samodova, Anatoly Sannikov, Elise Klouman   +4 more
doaj   +1 more source

Increased Hepatitis C Virus (HCV) Detection in Women of Childbearing Age and Potential Risk for Vertical Transmission - United States and Kentucky, 2011-2014.

MMWR. Morbidity and mortality weekly report, 2016
Hepatitis C virus (HCV) infection is a leading cause of liver-related morbidity and mortality (1). Transmission of HCV is primarily via parenteral blood exposure, and HCV can be transmitted vertically from mother to child. Vertical transmission occurs in
Alaya Koneru, Noele P. Nelson, S. Hariri, L. Canary, Kathy J. Sanders, Justin T. Maxwell, Xiaohua Huang, J. Leake, John W. Ward, C. Vellozzi   +9 more
semanticscholar   +1 more source

Challenges for HCV vaccine development in HIV–HCV coinfection

Expert Review of Vaccines, 2012
It is estimated that 4-5 million HIV-infected patients are coinfected with HCV. The impact of HIV on the natural course of HCV infection is deleterious. This includes a higher rate of HCV persistence and a faster rate of fibrosis progression. Coinfected patients show poor treatment outcome following standard HCV therapy.
Heidi Barth, Françoise Stoll-Keller, Samira Fafi-Kremer, Thomas F. Baumert, François Habersetzer, Mélanie Lambotin, Christiane Moog   +6 more
openaire   +3 more sources

Hepatitis and HIV Co-infection at University of Gondar Specialized Referral Hospital: Northwest Ethiopia

Hepatic Medicine: Evidence and Research, 2021
Meseret Ayelign,1 Melak Aynalem,2 Nega Berhane3 1Department of Molecular Biology, Specialized Referral Hospital, University of Gondar, Gondar, Ethiopia; 2Department of Hematology and Immunohematology, School of Biomedical and Laboratory Sciences, College
Ayelign M, Aynalem M, Berhane N
doaj  

Significance of IgG and IgM HCV antibody secretion in vitro in patients with chronic hepatitis C: Correlation with disease activity and response to interferon-α [PDF]

, 1994
H Löhr, Christopher Nagel, Hans‐Peter Dienes, B Simpson, Gerd Michel, Bernd Goergen, Karl‐Hermann Meyer zum Büschenfelde, Guido Gerken   +7 more
openalex   +1 more source

Virologic response following combined ledipasvir and sofosbuvir administration in patients with HCV genotype 1 and HIV co-infection.

Journal of the American Medical Association (JAMA), 2015
IMPORTANCE There is an unmet need for interferon- and ribavirin-free treatment for chronic hepatitis C virus (HCV) infection in patients co-infected with human immunodeficiency virus (HIV).
A. Osinusi, A. Osinusi, K. Townsend, A. Kohli, A. Kohli, Amy K. Nelson, Amy K. Nelson, Catherine A. Seamon, Eric G. Meissner, Eric G. Meissner, Dimitra Bon, R. Silk, R. Silk, C. Gross, C. Gross, A. Price, A. Price, Mohammad M. Sajadi, S. Sidharthan, Z. Sims, E. Herrmann, J. Hogan, Gebeyehu Teferi, R. Talwani, M. Proschan, V. Jenkins, D. Kleiner, Brad J. Wood, G. Subramanian, P. Pang, J. Mchutchison, M. Polis, A. Fauci, H. Masur, S. Kottilil, S. Kottilil   +35 more
semanticscholar   +1 more source

The value of polymorphism + 3725G / C TLR4 gene as a marker of liver fibrosis progression in patients with chronic hepatitis C

Journal of Education, Health and Sport, 2019
As a rule, chronic hepatitis C is manifested by the development of successive stages of liver fibrosis with the formation of eventually cirrhosis and liver cancer. However, in some patients the fibrosis progresses slowly, while in others there is a rapid
T. I. Bevz, D. F. Kyrychenko, G. A. Martynyuk   +2 more
doaj   +1 more source

Cellular immune response to hog cholera virus (HCV): T cells of immune pigs proliferate in vitro upon stimulation with live HCV, but the E1 envelope glycoprotein is not a major T-cell antigen [PDF]

, 1993
Tjeerd G. Kimman, A.T.J. Bianchi, G. Wensvoort, Taco Bruin, C Meliefste   +4 more
openalex   +1 more source