Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Biotechnology Progress, EarlyView.Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao +5 more
wiley +1 more source
Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. [PDF]
, 2006 Hepatic sinusoidal endothelial cells are unique among endothelial cells in their ability to internalize and process a diverse range of antigens. DC-SIGNR, a type 2 C-type lectin expressed on liver sinusoids, has been shown to bind with high affinity to ...
Adam Jennings +61 more
core +2 more sources
Cancer Communications, EarlyView.Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is anticipated to become the leading cause of hepatocellular carcinoma (HCC). Accumulating evidence indicates that N6‐methyladenosine (m6A)‐modified circular RNAs (circRNAs) play key roles in tumor malignant progression.
Jingbo Fu +22 more
wiley +1 more source
The efficiency and safety of anti-Helicobacter pylori therapy in patients with concomitant chronic hepatitis C [PDF]
Терапевтический архив, 2016 Aim. To evaluate the efficiency and safety of two eradication therapy (ET) regimens for Helicobacter pylori infection in patients with concomitant chronic hepatitis C (CHC) in relation to the stage of liver fibrosis (LF). Subjects and methods.
D N Andreev +4 more
doaj
Cryoglobulinemia and hepatitis C virus
Журнал инфектологии, 2014 The review presents recent data on cryoglobulinemiaassociated with a hepatitis C virus: prevalence, pathogenesis, clinical manifestations, laboratory diagnostics, approaches to therapy.
N. V. Dunaeva, E. V. Esaulenko
doaj +1 more source
Parallel and overlapping Human Immunodeficiency Virus, Hepatitis B and C virus Infections among pregnant women in the Federal Capital Territory, Abuja, Nigeria [PDF]
, 2009 Background: Risk factors that are associated with HIV infection are also associated with HBV and HCV infections in sub-Saharan Africa. The HIV-infected pregnant cohort represents a unique population and infection with the hepatitis virus is considered a ...
Bassey, EB, Moses, AE, Udo, SM, Umo, AN
core
Complete replication of hepatitis C virus in cell culture. [PDF]
, 2005 Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research progress on this important human pathogen.
Burton, Dennis R +10 more
core +1 more source
Gastroenterology, 2015 BACKGROUND & AIMS Patients with detectable hepatitis C virus (HCV) RNA at the time of liver transplantation universally experience recurrent HCV infection.
Michael P. Curry +24 more
semanticscholar +1 more source
Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds
ChemMedChem, EarlyView.Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis +3 more
wiley +1 more source
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. [PDF]
, 2008 Hepatitis C virus (HCV) is an enveloped positive-stranded RNA hepatotropic virus. HCV pseudoparticles infect liver-derived cells, supporting a model in which liver-specific molecules define HCV internalization.
Balfe, Peter +12 more
core +2 more sources