Exploring Plant‐Derived Nutraceuticals as Potential SARS CoV‐2 Mpro Inhibitors
Food Chemistry International, EarlyView.The search for plant derived anti‐SARS‐CoV‐2 Mpro compounds starts from food plants and spices as rich sources of bioactive compounds. Both in silico screening and experimental validation are essential to assess their therapeutic potential, leading to candidates for drug development and dietary integration.
Shaza S. Issa, Tatiana V. Matveeva
wiley +1 more source
Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]
, 2017 Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath +9 more
core +2 more sources
Marine Algae‐Derived Bioactives: A Sustainable Resource for the Food and Agriculture Industries
Food Frontiers, EarlyView.Algae are widely used in food and agriculture due to their bioactive compounds and are an eco‐friendly natural preservative and low carbon farming method. However, the problems regarding safety and acceptance still remain as tools like nanotechnology make improvements.
Sara Chadorshabi +3 more
wiley +1 more source
Oncotarget, 2015 Acute infection with hepatitis C virus (HCV) is cleared in about 30% of cases with CD8+ T-cells being the main effector cells in viral elimination. Yet, about 70% of patients progress to chronic HCV infection that can result in chronic immunopathology. This immune-mediated liver diseases can progress to liver cirrhosis and ultimately to hepatocellular ...
Schuch, Anita +2 more
openaire +4 more sources
Supporting children with genetic syndromes in the classroom: the example of 22q deletion syndrome [PDF]
, 2013 An increasing number of children are likely to have a known genetic cause for their special educational needs. One such genetic condition is 22q11.2 deletion syndrome (22qDS), a genetic syndrome associated with early speech and language difficulties ...
Reilly, C, Stedman, L
core +1 more source
Challenges for HCV vaccine development in HIV–HCV coinfection
Expert Review of Vaccines, 2012 It is estimated that 4-5 million HIV-infected patients are coinfected with HCV. The impact of HIV on the natural course of HCV infection is deleterious. This includes a higher rate of HCV persistence and a faster rate of fibrosis progression. Coinfected patients show poor treatment outcome following standard HCV therapy.
Heidi Barth +6 more
openaire +3 more sources
Association of multiple mutations in NS5A and NS5B genes and resistance to direct-acting antivirals in chronically infected Egyptian patients with Hepatitis C virus Genotype 4a [PDF]
Novel Research in Microbiology JournalApproximately 71 million people worldwide are supposed to have chronic hepatitis C virus (CHCV). New direct-acting antiviral (DAA) medications have been used, which helped successfully in complete treatment of CHCV and achieved a sustained virological ...
Gehad M. Mohamed +3 more
doaj +1 more source
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure. [PDF]
, 2013 MicroRNAs (miRNAs) typically downregulate protein expression from target mRNAs through limited base-pairing interactions between the 5' 'seed' region of the miRNA and the mRNA 3' untranslated region (3'UTR). In contrast to this established mode of action,
Doudna, Jennifer A, Mortimer, Stefanie A
core +1 more source
Cellular immune response to hog cholera virus (HCV): T cells of immune pigs proliferate in vitro upon stimulation with live HCV, but the E1 envelope glycoprotein is not a major T-cell antigen [PDF]
, 1993 Tjeerd G. Kimman +4 more
openalex +1 more source