Results 171 to 180 of about 425,993 (391)

Assessment of the Prevalence of Markers of Monoinfection with Hepatitis C Virus and Coinfection with Hepatitis C and B Viruses among the Personnel of Medical Institutions of an Endemic Region

Эпидемиология и вакцинопрофилактика
Relevance. Parenteral viral hepatitis B (HBV) and C (HCV) affect not only millions of people, but also healthcare workers due to professional contacts, which lead to the progression of liver pathology and a reduction in medical activity. Numerous studies
M. P. Kostinov, N. A. Magomedova, I. A. Khrapunova, A. V. Linok, E. Yu. Malinnikova, G. I. Alatortseva, L. N. Pritvorova, L. N. Nesterenko, I. I. Amiantova, V. V. Dotsenko, V. Yu. Kabargina, V. B. Polishchuk, M. N. Loktionova, A. A. Besshaposhnikova   +13 more
doaj   +1 more source

Treatment of HCV infection by targeting microRNA.

New England Journal of Medicine, 2013
H. Janssen, H. Reesink, E. Lawitz, S. Zeuzem, M. Rodríguez-Torres, K. Patel, A. J. van der Meer, A. Patick, Alice Chen, Yi Zhou, R. Persson, B. King, S. Kauppinen, A. Levin, M. Hodges   +14 more
semanticscholar   +1 more source

Characterization of PIVKA‐II Molecular Forms via Size Exclusion Chromatography and Hydrophobic Interaction Chromatography in HCC Patients

Journal of Clinical Laboratory Analysis, EarlyView.
PIVKA‐II comprises two heterogeneous molecular forms with different levels regarding hydrophobicity, and PIVKA‐II in serum and plasma exists as distinct molecular forms with varying levels. ABSTRACT Background Protein induced by the absence of vitamin K or antagonist‐II (PIVKA‐II) is an important serological biomarker for the diagnosis of ...
Yoshiyuki Kitamura, Katsumi Aoyagi
wiley   +1 more source

Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection.

New England Journal of Medicine, 2014
N. Afdhal, S. Zeuzem, P. Kwo, M. Chojkier, N. Gitlin, M. Puoti, M. Romero‐Gomez, J. Zarski, K. Agarwal, P. Buggisch, G. Foster, N. Bräu, M. Buti, I. Jacobson, G. Subramanian, Xiao Ding, H. Mo, Jenny C. Yang, P. Pang, W. Symonds, J. Mchutchison, A. Muir, A. Mangia, P. Marcellin   +23 more
semanticscholar   +1 more source

HCV resistance [PDF]

Retrovirology, 2012
openaire   +2 more sources

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

The Journal of Clinical Pharmacology, EarlyView.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima, Akihide Tsujimoto, Masako Saito, Jun Takeda, Makiko Natori, Satoshi Shoji   +5 more
wiley   +1 more source

Enzyme-linked Immunosorbent Assay for Coronaviruses HCV 229E and MHV 3

, 1980
C. A. Kraaijeveld, M. H. Madge, M. R. Macnaughton   +2 more
openalex   +1 more source

Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: Different patterns of response to interferon treatment [PDF]

, 1993
Beatriz Gil
openalex   +1 more source

Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection

New England Journal of Medicine, 2017
H. Ford, M. Bourlière, S. Gordon, S. Flamm, C. Cooper, A. Ramji, M. Tong, N. Ravendhran, J. Vierling, T. Tran, S. Pianko, M. Bansal, V. Ledinghen, R. Hyland, L. Stamm, H. Dvory‐Sobol, E. Svarovskaia, Jie Zhang, K. C. Huang, G. Subramanian, D. Brainard, J. Mchutchison, E. Verna, P. Buggisch, C. Landis, Z. Younes, M. Curry, S. Strasser, E. Schiff, K. Reddy, M. Manns, K. Kowdley, S. Zeuzem   +32 more
semanticscholar   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

The Journal of Clinical Pharmacology, EarlyView.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou, Alex Vo, Gaetano Morelli, Maureen Montrond, Shannan Lynch, Keith Pietropaolo, Bruce Belanger, Arantxa Horga, Nancy Agrawal, Janet Hammond   +9 more
wiley   +1 more source