Results 301 to 310 of about 434,626 (386)

Human Spinal Cord GABAergic Neural Progenitor Cell

open access: yes
Cell Proliferation, EarlyView.
Jia Xu   +23 more
wiley   +1 more source

Clinical Outcomes of Reduced‐Dose Cabozantinib as Third‐ or Later‐Line Therapy After Immune Checkpoint Inhibitors in Advanced Hepatocellular Carcinoma: A Real‐World Study

open access: yesHepatology Research, EarlyView.
In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya   +13 more
wiley   +1 more source

The Hepatic Steatosis Diagnostic Performance Using Attenuation Imaging With the Magnetic Resonance Imaging‐Based Proton Density Fat Fraction as the Reference Standard: A Large, Prospective, Multicenter Cohort Study in Japan

open access: yesHepatology Research, EarlyView.
In a multicenter cohort of 1059 patients, attenuation imaging (ATI) showed good diagnostic performance and strong correlation with MRI‐PDFF, supporting its value as a noninvasive method for evaluating hepatic steatosis. ABSTRACT Background Attenuation imaging (ATI) is used for the noninvasive diagnosis of hepatic steatosis (HS) based on the ultrasound ...
Takashi Nishimura   +24 more
wiley   +1 more source

Retreatment of Direct Acting Agents (DAAs) After Initial DAA Failure in Hepatitis C Patients

open access: yesHepatology Research, EarlyView.
ABSTRACT Background and Aims Glecaprevir/pibrentasvir (GLE/PIB) and sofosbuvir/ledipasvir (SOF/LDV) are widely used as first‐line direct‐acting antiviral (DAA) regimens for chronic hepatitis C, achieving high virus eradication rates. However, a small proportion of patients experience treatment failure, and the optimal retreatment strategies for such ...
Nobuharu Tamaki   +10 more
wiley   +1 more source

Expression of CD38 on resting peripheral iNKT cells defines an immature subpopulation with distinct functionality in humans

open access: yesImmunology &Cell Biology, EarlyView.
In this study, we characterize a distinct subpopulation of undifferentiated invariant natural killer T (iNKT) cells in the peripheral blood of healthy adults, which are characterized by CD38 expression in a resting state. This CD38+ subset closely resembles iNKT cells from cord blood and thymus, exhibiting a unique cytokine profile and alterations in ...
Christopher Menne   +13 more
wiley   +1 more source

Study of HCV Antibody (2nd Report)

open access: bronze, 1994
岡野 裕   +5 more
openalex   +2 more sources

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima   +9 more
wiley   +1 more source

Designing a novel radial basis neural structure for solving the dynamical hepatitis C virus model. [PDF]

open access: yesSci Rep
Sabir Z   +5 more
europepmc   +1 more source

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