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Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV-related steatosis

Atherosclerosis, 2012
HCV and NAFLD are associated with atherosclerosis in general population. The prevalence of atherosclerosis in chronic hepatitis C (CHC) patients is unknown. We hypothesized that HCV per se and HCV-related steatosis could favour atherosclerosis. Thus, in CHC patients we assessed: (a) the prevalence of atherosclerosis; (b) the role of HCV, cardio ...
ADINOLFI, Luigi Elio   +8 more
openaire   +4 more sources

HCV virology and diagnosis

Clinics and Research in Hepatology and Gastroenterology, 2021
Hepatitis C virus (HCV) infection is a major cause of severe liver disease including chronic hepatitis, cirrhosis and hepatocellular carcinoma. The HCV burden in public health is estimated at about 71 million people worldwide by World Health Organization (WHO) with at least 400,000 people that died every year from HCV disease [1].
Alexandra Ducancelle   +4 more
openaire   +3 more sources

HCV and Cryoglobulinemia

2004
Discussion of the etiologic role of HCV in mixed ...
FERRI, Clodoveo, Bombardieri S.
openaire   +2 more sources

Increasing Utilization and Excellent Initial Outcomes Following Liver Transplant of Hepatitis C Virus (HCV)‐Viremic Donors Into HCV‐Negative Recipients: Outcomes Following Liver Transplant of HCV‐Viremic Donors

Hepatology, 2019
Direct‐acting antiviral (DAA) therapy has altered the frequency and outcome of liver transplantation (LT) for hepatitis C virus (HCV). The high efficacy and tolerability of DAA therapy has also created a rationale for utilizing HCV‐viremic (HCV‐RNA ...
T. Cotter   +7 more
semanticscholar   +1 more source

HBV/HCV Coinfection in the Era of HCV-DAAs

Clinics in Liver Disease, 2019
Epidemiologic studies suggest that 10% to 15% of patients infected with hepatitis C virus (HCV) are coinfected with hepatitis B virus (HBV) in the United States as a result of the shared modality of transmission, but the true prevalence is not known.
Mohamed El Kabany   +2 more
openaire   +3 more sources

HCV-related autoimmune and neoplastic disorders: the HCV syndrome

Digestive and Liver Disease, 2007
Hepatitis C virus (HCV) chronic infection may be associated with a great number of both hepatic and extrahepatic manifestations. HCV lymphotropism is responsible for poly-oligoclonal B-lymphocyte expansion, which is the common underlying alteration in a significant percentage of HCV-infected individuals.
FERRI, Clodoveo   +7 more
openaire   +7 more sources

Efficient initiation of HCV RNA replication in cell culture.

Science, 2000
Hepatitis C virus (HCV) infection is a global health problem affecting an estimated 170 million individuals worldwide. We report the identification of multiple independent adaptive mutations that cluster in the HCV nonstructural protein NS5A and confer ...
K. Blight, A. Kolykhalov, C. Rice
semanticscholar   +1 more source

HCV-specific lymphocyte responses in individuals with positive anti-HCV but negative HCV-RNA

Journal of Clinical Virology, 2015
Hepatitis C virus (HCV) status cannot be reliably predicted in anti-HCV positive/HCV-RNA negative individuals who may either have recovered spontaneously or have a false-positive test due to antibody cross-reaction. Investigating T lymphocyte responses in individuals with different HCV status may help understand the cellular immune mechanisms ...
Sili, Uluhan   +7 more
openaire   +4 more sources

HCV-related autoimmune disorders in HCV chronic infection.

La Clinica terapeutica, 2013
Patients with hepatitis C virus (HCV) chronic infection may develop a great number of extrahepatic manifestations. Among these latter, mixed cryoglobulinemia (MC) represents the prototype of HCV-associated autoimmune-lymphoproliferative disorders. Other rheumatological manifestations of HCV chronic infection are Siögren syndrome, arthritis and CREST ...
Ferrari S. M.   +6 more
openaire   +5 more sources

Epidemiology of HCV Infection

Current Pharmaceutical Design, 2008
It is estimated that approximately 130-170 million people worldwide are infected with hepatitis C virus (HCV). According to data from WHO community and blood donor surveys, the African and Eastern Mediterranean countries report the highest prevalence rates (>10%).
BALDO, VINCENZO   +3 more
openaire   +4 more sources

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