Results 1 to 10 of about 5,787 (90)

C38 - Évaluation in vitro de l'activité antibactérienne d'un pansement chargé d'extraits de plantes

open access: yesJournal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction : Les plaies infectées constituent un problème de santé publique du fait qu’elles peuvent prolonger la durée d’une hospitalisation. Les pansements utilisés dans leurs prises en charge contiennent souvent des antibactériens comme l’ion ...
M. DIOP   +9 more
doaj   +1 more source

C45 - Hydrogels oraux pH-sensibles contenant du phénobarbital pour une utilisation potentielle en pédiatrie

open access: yesJournal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction : Le but de l’étude était de développer des hydrogels oraux à base de chitosane pH- sensibles, capables de libérer le phénobarbital dans l'intestin grêle du nouveau-né.
Alphonse Rodrigue DJIBOUNE   +10 more
doaj   +1 more source

C42 - Optimisation d’une formule de comprime matriciel à base de spiruline enrichi en vitamine C

open access: yesJournal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
La spiruline est une algue fortement consommée dans le monde comme complément alimentaire en raison de son grand potentiel nutritionnel. Elle se trouve toutefois exempte de vitamine C, une vitamine capitale pour le bon fonctionnement de l’organisme ...
Assogba Gabin ASSANHOU   +6 more
doaj   +1 more source

Effect of in vitro gastrointestinal digestion on the chemical composition and antioxidant properties of Ginkgo biloba leaves decoction and commercial capsules

open access: yesActa Pharmaceutica, 2022
In this study Ginkgo biloba leaves (GBL) decoction and commercial capsules were digested using an in vitro model. Thirty-six active compounds were identified and quantified by HPLC-ESI-MS analysis based on the MS/MS patterns (precursor ions and product ...
Zhou Yubo   +5 more
doaj   +1 more source

Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study

open access: yesActa Pharmaceutica, 2022
A good therapeutic alliance is relevant for healthcare providers exposed to patients’ suffering, especially since patients and physicians may understand the painful experience differently.
Barrachina Jordi   +7 more
doaj   +1 more source

Optimized D-α-tocopherol polyethylene glycol succinate/phospholipid self-assembled mixed micelles: A promising lipid-based nanoplatform for augmenting the antifungal activity of fluconazole

open access: yesActa Pharmaceutica, 2022
Fluconazole (FLZ) is the most widely used antifungal agent for treating cutaneous candidiasis. Although oral FLZ has been proved to be effective, the incidence of side effects necessitates the development of an effective formulation that could surpass ...
Badr-Eldin Shaimaa M.   +11 more
doaj   +1 more source

Effects of tranquilization therapy in elderly patients suffering from chronic non-communicable diseases: A meta-analysis

open access: yesActa Pharmaceutica, 2023
The current meta-analysis searched the literature connected to different tranquilizers used to treat elderly people and assessed it in terms of dose, types of outcomes and adverse effects, to determine a safe and acceptable tranquilizer and its optimal ...
Li Jing   +8 more
doaj   +1 more source

The opposite effect of convulsant drugs on neuronal and endothelial nitric oxide synthase – A possible explanation for the dual proconvulsive/anticonvulsive action of nitric oxide

open access: yesActa Pharmaceutica, 2023
Nitric oxide (NO) participates in processes such as endothelium-dependent vasodilation and neurotransmission/neuromodulation. The role of NO in epilepsy is controversial, attributing it to anticonvulsant but also proconvulsant properties.
Vega Rasgado Lourdes A.   +3 more
doaj   +1 more source

α1-Adrenoceptor agonist methoxamine inhibits base excision repair via inhibition of apurinic/apyrimidinic endonuclease 1 (APE1)

open access: yesActa Pharmaceutica, 2023
Methoxamine (Mox) is a well-known α1-adrenoceptor agonist, clinically used as a longer-acting analogue of epinephrine. 1R,2S-Mox (NRL001) has been also undergoing clinical testing to increase the canal resting pressure in patients with bowel incontinence.
Kohutova Aneta   +3 more
doaj   +1 more source

Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development

open access: yesActa Pharmaceutica, 2023
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. However, not all smokers develop the disease, indicating that genetic susceptibility could be
Baranasic Jurica   +9 more
doaj   +1 more source

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