Results 11 to 20 of about 6,006 (50)

Enteric coating of granules containing the probiotic Lactobacillus acidophilus

open access: yesActa Pharmaceutica, 2014
In the present study, a capsule formulation composed of enteric coated granules of Lactobacillus acidophilus ATCC 4962 was developed using Eudragit L30D-55 as enteric polymer.
Pyar Hassan, Peh Kok-Khiang
doaj   +1 more source

Amygdalin isolated from Amygdalus mongolica protects against hepatic fibrosis in rats

open access: yesActa Pharmaceutica, 2021
The aim of this research was to investigate the effect of amygdalin on hepatic fibrosis in rats. Amygdalin was purified and identified from the seeds of Amygdalus mongo lica.
Wang Jia   +5 more
doaj   +1 more source

Melatonin as a powerful antioxidant

open access: yesActa Pharmaceutica, 2021
Melatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of ...
Chrustek Agnieszka   +1 more
doaj   +1 more source

Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS

open access: yesActa Pharmaceutica, 2021
To evaluate the bioavailability of ellagic acid loaded super-saturatable self-microemulsifying drug delivery system (S-SMEDDS), its pharmacokinetic properties were studied in rats with an ultra-high performance liquid chromatography-quadrupole time-of ...
Wang Jinglong   +6 more
doaj   +1 more source

Quality-by-design in pharmaceutical development: From current perspectives to practical applications

open access: yesActa Pharmaceutica, 2021
Current pharmaceutical research directions tend to follow a systematic approach in the field of applied research and development. The concept of quality-by-design (QbD) has been the focus of the current progress of pharmaceutical sciences. It is based on,
Kovács Béla   +6 more
doaj   +1 more source

Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride

open access: yesActa Pharmaceutica, 2020
Green and sensitive spectrofluorometric methods have been developed and validated for the determination of timolol maleate (TML)/hydrochlorothiazide (HCT) and amiloride hydrochloride (AMH)/hydrochlorothiazide in tablets.
Wedian Fadel   +2 more
doaj   +1 more source

Antioxidant and antihyperglycemic activities of Scorzonera cinerea radical leaves in streptozocin-induced diabetic rats

open access: yesActa Pharmaceutica, 2021
Scorzonera species are used for treating various diseases. They are consumed raw, especially in the spring, and have nutritious and dietetic values. This study evaluated the antidiabetic and antioxidant effects of ethanolic extracts of Scorzonera cinerea
Temiz Mehmet Ali
doaj   +1 more source

Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives

open access: yesActa Pharmaceutica, 2014
Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium- 5-thiolate (10a,b) with chloroacetic acid or methyl iodide: 1,3,4-thiadiazolium-5 ...
Luis José A. S.   +7 more
doaj   +1 more source

Effect of rutin from tartary buckwheat sprout on serum glucose-lowering in animal model of type 2 diabetes

open access: yesActa Pharmaceutica, 2016
This study investigates the anti-diabetic effects of rutin from tartary buckwheat sprout in type 2 diabetes mouse model. The rutin content in tartary buckwheat sprout (TBS) is five times higher than that found in common buckwheat sprout (CBS) as evident ...
Lee Dong-Gi   +9 more
doaj   +1 more source

Determination of remifentanil in neonatal dried blood spots by liquid chromatography-tandem mass spectrometry

open access: yesActa Pharmaceutica
Remifentanil is an ultra-short-acting synthetic opioid-class analgesic which might be increasingly used “off-label” as pain management during labour.
Trontelj Jurij   +2 more
doaj   +1 more source

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