Results 21 to 30 of about 6,006 (50)

Forecasting the effect of water gastric emptying patterns on model drug release in an in vitro glass-bead flow-through system

Acta Pharmaceutica
Oral solid dosage forms are most frequently administered with a glass of water which empties from the stomach relatively fast, but with a certain variability in its emptying kinetics.
Felicijan Tjaša, Bogataj Marija
doaj   +1 more source

Attitudes of physicians, nurses and pharmacists concerning the development of clinical pharmacy activities in a university hospital

Acta Pharmaceutica, 2014
It is essential to identify the expectations of physicians and nurses regarding clinical pharmacy (CP) services before its introduction in a hospital, because it is known that their expectations can substantially differ from the pharmacists’ point of ...
Čufar Andreja, Locatelli Igor, Mrhar Aleš   +2 more
doaj   +1 more source

Lipid-based systems with precipitation inhibitors as formulation approach to improve the drug bioavailability and/or lower its dose: a review

Acta Pharmaceutica
Lipid-based systems, such as self-microemulsifying systems (SMEDDS) are attracting strong attention as a formulation approach to improve the bioavailability of poorly water-soluble drugs.
Kovačević Mila, Gašperlin Mirjana, Pobirk Alenka Zvonar   +2 more
doaj   +1 more source

Use of compounded dispersing media for extemporaneous pediatric syrups with candesartan cilexetil and valsartan

Acta Pharmaceutica, 2014
Available tablets or capsules for adults are often used to prepare extemporaneously formulated medicines appropriate for children. The most acceptable drug forms in pediatric population are oral liquids and pharmacists use commercial dispersing media to ...
Musko Monika, Sznitowska Malgorzata
doaj   +1 more source

Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma

Acta Pharmaceutica
The aim of this study was to determine whether there are differences in complete blood count parameters (CBC) and inflammation-related biomarkers, MPV/PC, PLR, NLR, LWR, LMR, NMR, and LCR, among patients with colorectal carcinoma (CRC) and patients with ...
Koržinek Martha, Ćelap Ivana, Fabijanec Marija, Žanić Tena, Ljubičić Neven, Baršić Neven, Verbanac Donatella, Barišić Karmela, Rajković Marija Grdić   +8 more
doaj   +1 more source

Dendrimer functionalized folate-targeted gold nanoparticles for luciferase gene silencing in vitro: A proof of principle study

Acta Pharmaceutica, 2019
Use of exogenous small interfering RNA (siRNA) has shown potential in gene silencing. The need for target-specific siRNA delivery vehicles is crucial to successful gene silencing. This study is aimed at developing and evaluating the safety and efficiency
Mbatha Londiwe Simphiwe, Maiyo Fiona Chepkoech, Singh Moganavelli   +2 more
doaj   +1 more source

Advancements in electron paramagnetic resonance (EPR) spectroscopy: A comprehensive tool for pharmaceutical research

Acta Pharmaceutica
Electron paramagnetic resonance (EPR) spectroscopy has long been established across various scientific disciplines for characterizing organic radicals, organometallic complexes, protein structures and dynamics, polymerization processes, and radical ...
Bešić Erim, Rajić Zrinka, Šakić Davor   +2 more
doaj   +1 more source

Evaluation of phenylethylamine type entactogens and their metabolites relevant to ecotoxicology – a QSAR study

Acta Pharmaceutica, 2019
The impact of the selected entactogens and their o-quinone metabolites on the environment was explored in QSAR studies by the use of predicted molecular descriptors, ADMET properties and environmental toxicity parameters, i.e., acute toxicity in ...
Takač Milena Jadrijević-Mladar, Magina Joao Daniel Casimiro, Takač Tin   +2 more
doaj   +1 more source

SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1

Acta Pharmaceutica, 2020
The incidence of mortality of prostate cancer (PCa) has been an uptrend in recent years. Our previous study showed that the sex-determining region Y-box 7 (SOX7) was low-expressed and served as a tumor suppressor in PCa cells.
Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin   +5 more
doaj   +1 more source

Advanced flow cell design for in vitro release testing of mucoadhesive buccal films

Acta Pharmaceutica, 2020
Films for buccal application are a slowly emerging new platform for drug delivery. There remains a lack of analytical techniques for the determination of in vitro active pharmaceutical ingredient release. The aim here was to develop an alternative method
Grilc Blaž, Zdovc Jurij, Planinšek Odon   +2 more
doaj   +1 more source