Results 231 to 240 of about 116,207 (325)

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation [PDF]

, 2017
Helia N. Sanchez, Tian Shen, Dawn Garcia, Zhao Lai, Paolo Casali, Hong Zan   +5 more
openalex   +1 more source

Causal Pathways Linking Gut Microbiota, Serum Metabolites, and Meningioma Risk: A Mendelian Randomization Analysis

Brain and Behavior, Volume 16, Issue 2, February 2026.
This Mendelian randomization analysis elucidates causal pathways linking gut microbiota and serum metabolites to meningioma. We identified specific risk factors and found that arachidonic acid potentially mediates the effect of CAG−873 sp001701165 on meningioma risk.
Xuanli Gong, Jinxiang Zhang, Mengjiao He, Xiaochen Zhang, Kelan Wang, Yulu Yang, Qingyun Zhao, Xin Zhao, Wei Zou   +8 more
wiley   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Research progress on histone deacetylases in peritoneal dialysis-associated peritoneal fibrosis. [PDF]

Ren Fail
Qiu W, Chen J, Behera TR, Huang Y, Chu C, Xu B, Shen Q, Yan J.   +7 more
europepmc   +1 more source

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review). [PDF]

Oncol Rep
Suwanwong Y, Ploensil P.
europepmc   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

Rare DMD Gene Duplication in a Lebanese Child With Duchene Muscular Dystrophy

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT A five‐year‐old boy with clinical features of Duchenne muscular dystrophy was found to have a rare de novo DMD exon 2–9 duplication. Reporting such atypical duplications improves genotype–phenotype interpretation and highlights the need for multidisciplinary care, particularly in resource‐limited settings.
Nada Assaf, Jeanette El Hajj, Jana Doghman, Fatima Hussein, Simone Khalifeh   +4 more
wiley   +1 more source

Glutamine relieves feed restriction-induced ruminal epithelial function damage through histone lysine lactylation in yaks. [PDF]

J Anim Sci Biotechnol
Yue Z, Shi L, Wang Z, Hu R, Peng Q, Zou H, Xiao J, Jiang Y, Wu F, Tang Y.   +9 more
europepmc   +1 more source

DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu, Yuzhu Ma, Yueying Gao, Yao Chen, Xinyu Li, Yue Wu, Meiling Sun, Qizhao Li, Yanhong Zhao, Shuqian Xu, Shengjin Fan, Yongsheng Li, Huitao Fan   +12 more
wiley   +1 more source

The impact of histone deacetylase inhibition on neurobehavioural outcomes in preclinical models of traumatic and non-traumatic spinal cord injury: a systematic review. [PDF]

Front Immunol
Jagodzinska NM, Cole C, Brannigan J, Chintapalli R, Davies BM, Kotter MR, Mowforth OD.   +6 more
europepmc   +1 more source