Results 21 to 30 of about 5,136 (200)

Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells

open access: yesGenes and Environment, 2019
Introduction Diagnostic and therapeutic ionizing radiation (IR) is one of the well known long term risk factors of breast cancer. Extremely lethal consequences of IR causes double-strand breaks, which are mainly responsible for genomic instability ...
Gugalavath Shailender   +3 more
doaj   +1 more source

Pharmacological Activation of Autophagy Restores Cellular Homeostasis in Ultraviolet-(B)-Induced Skin Photodamage

open access: yesFrontiers in Oncology, 2021
Ultraviolet (UV) exposure to the skin causes photo-damage and acts as the primary etiological agent in photo-carcinogenesis. UV-B exposure induces cellular damage and is the major factor challenging skin homeostasis.
Sheikh Ahmad Umar   +15 more
doaj   +1 more source

Cardiac and Vascular Remodeling After 6 Months of Therapy With Sacubitril/Valsartan: Mechanistic Insights From Advanced Echocardiographic Analysis

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundEffects of Sacubitril/Valsartan (S/V) on left ventricular (LV) mechanics and ventricular-arterial coupling in patients with heart failure with reduced ejection fraction (HFrEF) are not completely understood.
Sara Monosilio   +13 more
doaj   +1 more source

Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway

open access: yesFrontiers in Oncology, 2020
The treatment of melanoma has remained a difficult challenge. Targeting the tumor stroma has recently attracted attention for developing novel strategies for melanoma therapy.
Tingjian Zu   +15 more
doaj   +1 more source

Gelam Honey Protects against Gamma-Irradiation Damage to Antioxidant Enzymes in Human Diploid Fibroblasts

open access: yesMolecules, 2013
The present study was designed to determine the radioprotective effects of Malaysian Gelam honey on gene expression and enzyme activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) of human diploid fibroblasts (HDFs ...
Suzana Makpol   +5 more
doaj   +1 more source

The Changing Character of Carbon in Fluids with Pressure

open access: yesGeophysical Monograph Series, Page 259-269., 2020

This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.

Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions

Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Dimitri Sverjensky   +2 more
wiley  

+1 more source

Genome-Wide CRISPR Screen Identifies Host Factors Required by Toxoplasma gondii Infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Toxoplasma gondii are obligate intracellular protoza, and due to their small genome and limited encoded proteins, they have to exploit host factors for entry, replication, and dissemination.
Shui-Zhen Wu   +5 more
doaj   +1 more source

Distributed image retrieval with colour and keypoint features

open access: yesJournal of Information and Telecommunication, 2019
Content-based image retrieval poses many problems to computer systems. The content of images has to be described by some feature extraction methods. As image databases are often very large, they are sometimes to complex to be processed by traditional ...
Michał Ła̧giewka   +2 more
doaj   +1 more source

Deploying Apache Spark virtual clusters in cloud environments using orchestration technologies

open access: yesТруды Института системного программирования РАН, 2018
Apache Spark is a framework providing fast computations on Big Data using MapReduce model. With cloud environments Big Data processing becomes more flexible since they allow to create virtual clusters on-demand. One of the most powerful open-source cloud
O. . Borisenko   +2 more
doaj   +1 more source

Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin

open access: yesJournal of Ginseng Research, 2020
Background: The cellular senescence of primary cultured cells is an irreversible process characterized by growth arrest. Restoration of senescence by ginsenosides has not been explored so far.
Ik-Soon Jang   +10 more
doaj   +1 more source

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