Results 31 to 40 of about 8,808 (189)

Cardiac and Vascular Remodeling After 6 Months of Therapy With Sacubitril/Valsartan: Mechanistic Insights From Advanced Echocardiographic Analysis

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundEffects of Sacubitril/Valsartan (S/V) on left ventricular (LV) mechanics and ventricular-arterial coupling in patients with heart failure with reduced ejection fraction (HFrEF) are not completely understood.
Sara Monosilio   +13 more
doaj   +1 more source

Semantic web service-based messaging framework for prediction of fitness data using Hadoop distributed file system

open access: yesAutomatika, 2019
Big data is coined as word of mouth in this era due to the generation of huge volume of data every second from multiple sources like logs, web sources, and sensors, electrical and electronic devices.
R. Sethuraman, T Sasiprabha
doaj   +1 more source

Genome-Wide CRISPR Screen Identifies Host Factors Required by Toxoplasma gondii Infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Toxoplasma gondii are obligate intracellular protoza, and due to their small genome and limited encoded proteins, they have to exploit host factors for entry, replication, and dissemination.
Shui-Zhen Wu   +5 more
doaj   +1 more source

Ordinal Optimization-Based Performance Model Estimation Method for HDFS

open access: yesIEEE Access, 2020
Modeling and analyzing the performance of distributed file systems (DFSs) benefit the reliability and quality of data processing in data-intensive applications. Hadoop Distributed File System (HDFS) is a typical representative of DFSs.
Tian Ma, Feng Tian, Bo Dong
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Titanium‐Catalyzed Defluorination of Poly(Vinyl Fluoride) and Poly(Vinylidene Fluoride) Under Friedel–Crafts Conditions

open access: yesAngewandte Chemie, EarlyView.
Cationic titanium sandwich catalysts display exceptional activity in the hydrodefluorination of Csp3─F bonds, in the presence of silanes and aromatic solvents (turnover numbers up to 3000). As a result, they can be used to defluorinate challenging fluoropolymers, such as poly(vinyl fluoride) (PVF) or poly(vinylidene fluoride) (PVDF).
Louis Le Moigne   +9 more
wiley   +2 more sources

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

open access: yesAdvanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee   +6 more
wiley   +1 more source

Protopine/Gemcitabine Combination Induces Cytotoxic or Cytoprotective Effects in Cell Type-Specific and Dose-Dependent Manner on Human Cancer and Normal Cells

open access: yesPharmaceuticals, 2021
The natural alkaloid protopine (PRO) exhibits pharmacological properties including anticancer activity. We investigated the effects of PRO, alone and in combination with the chemotherapeutic gemcitabine (GEM), on human tumor cell lines and non-tumor ...
Mercedes Garcia-Gil   +10 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Preferential Interfacial Engineering of Hydrogels via Interdigitated Nanoparticle Assembly

open access: yesAdvanced Functional Materials, EarlyView.
Robust surface functionalization of hydrogel surfaces is performed via interdigitated metal nanoparticle assembly, inducing strong affinity with the hydrogel matrix. The partially exposed nanoparticle domains act as interfacial nanobridges that mediate both chemical and physical bonding with diverse materials, including small molecules, fluorous ...
Hyeonjin Kim   +11 more
wiley   +1 more source

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