Results 1 to 10 of about 60,778 (163)
Puerarin blocks the aging phenotype in human dermal fibroblasts.
PLoS ONE, 2021 Dermal fibroblast aging contributes to aging-associated functional defects in the skin since dermal fibroblasts maintain skin homeostasis by interacting with the epidermis and extracellular matrix.
Yuki Kamiya +4 more
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Nanomaterials, 2019 Herein, the cytotoxicity, cellular uptake and wound healing of human dermal fibroblasts were investigated upon treatment with gold nanorods (GNR) decorated with different ligands. Neutral and cationic poly ethylene glycol (PEG)-decorated GNR demonstrated
Nouf N. Mahmoud +3 more
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α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts
Molecules, 2019 Ultraviolet (UV) light-induced wrinkle formation is a major dermatological problem and is associated with alteration in collagen. Here, we investigated the potential of α-ionone, a naturally occurring aromatic compound, in regulation of UVB-induced ...
Tao Tong +4 more
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The effect of aging in primary human dermal fibroblasts.
PLoS ONE, 2019 Skin aging is a complex process, and alterations in human skin due to aging have distinct characteristic as compared to other organs. The aging of dermal cells and the biological mechanisms involved in this process are key areas to understand skin aging.
Juliana Carvalhães Lago +1 more
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Pathogenesis of Photoaging in Human Dermal Fibroblasts
International Journal of Dermatology and Venerology, 2020 Ling-Yi Lee, Sheng-Xiu Liu
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Cosmetics, 2022 Aminocarbonyl proteins increase with age in the dermal layer. Gene Chip analysis of mRNA expression in human dermal fibroblasts cultured on collagen gels treated with glyceraldehyde as an aminocarbonyl protein and on untreated collagen gels showed a ...
Kazuhisa Maeda, Shiori Yoshida
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Regulation of dermal fibroblasts by human neutrophil peptides
Scientific Reports, 2023 AbstractHuman neutrophil peptides (HNPs) can induce cell proliferation and activation so their growth promoting activities may have potential clinical benefit. This study investigated the effects of HNPs on human dermal fibroblasts. Differential gene expression in HNP-treated cells and genes involved in regulating intracellular pathways were explored ...
Nattarika Niwetbowornchai +8 more
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JID Innovations, 2022 CCN2, a member of the CCN family of matricellular proteins, is a key mediator and biomarker of tissue fibrosis. We previously reported that CCN2 is significantly reduced in aged human dermis, which contributes to dermal aging through the downregulation ...
Zhaoping Qin +3 more
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Human dermal fibroblasts in psychiatry research [PDF]
Neuroscience, 2016 In order to decipher the disease etiology, progression and treatment of multifactorial human brain diseases we utilize a host of different experimental models. Recently, patient-derived human dermal fibroblast (HDF) cultures have re-emerged as promising in vitro functional system for examining various cellular, molecular, metabolic and (patho ...
S. Kálmán +3 more
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Cells, 2021 The dermis is the connective layer between the epidermis and subcutis and harbours nerve endings, glands, blood vessels, and hair follicles. The most abundant cell type is the fibroblast.
Kimberly Nickel +4 more
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