Results 21 to 30 of about 7,662,162 (290)

Internal iamin structures within G1 nuclei of human dermal fibroblasts [PDF]

open access: yes, 1993
The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis.
Kill, IR   +3 more
core   +6 more sources

Pathogenesis of Photoaging in Human Dermal Fibroblasts

open access: yesInternational Journal of Dermatology and Venerology, 2020
Ling-Yi Lee, Sheng-Xiu Liu
doaj   +2 more sources

Involvement of Aquaporin 1 in the Motility and in the Production of Fibrillin 1 and Type I Collagen of Cultured Human Dermal Fibroblasts

open access: yesCosmetics, 2022
Aminocarbonyl proteins increase with age in the dermal layer. Gene Chip analysis of mRNA expression in human dermal fibroblasts cultured on collagen gels treated with glyceraldehyde as an aminocarbonyl protein and on untreated collagen gels showed a ...
Kazuhisa Maeda, Shiori Yoshida
doaj   +1 more source

Human dermal fibroblasts in psychiatry research [PDF]

open access: yesNeuroscience, 2016
In order to decipher the disease etiology, progression and treatment of multifactorial human brain diseases we utilize a host of different experimental models. Recently, patient-derived human dermal fibroblast (HDF) cultures have re-emerged as promising in vitro functional system for examining various cellular, molecular, metabolic and (patho ...
S. Kálmán   +3 more
openaire   +4 more sources

Age-Related Downregulation of CCN2 Is Regulated by Cell Size in a YAP/TAZ-Dependent Manner in Human Dermal Fibroblasts: Impact on Dermal Aging

open access: yesJID Innovations, 2022
CCN2, a member of the CCN family of matricellular proteins, is a key mediator and biomarker of tissue fibrosis. We previously reported that CCN2 is significantly reduced in aged human dermis, which contributes to dermal aging through the downregulation ...
Zhaoping Qin   +3 more
doaj   +1 more source

Evaluation of Immunomodulatory Responses and Changed Wound Healing in Type 2 Diabetes—A Study Exploiting Dermal Fibroblasts from Diabetic and Non-Diabetic Human Donors

open access: yesCells, 2021
The dermis is the connective layer between the epidermis and subcutis and harbours nerve endings, glands, blood vessels, and hair follicles. The most abundant cell type is the fibroblast.
Kimberly Nickel   +4 more
doaj   +1 more source

Regulation of dermal fibroblasts by human neutrophil peptides

open access: yesScientific Reports, 2023
AbstractHuman neutrophil peptides (HNPs) can induce cell proliferation and activation so their growth promoting activities may have potential clinical benefit. This study investigated the effects of HNPs on human dermal fibroblasts. Differential gene expression in HNP-treated cells and genes involved in regulating intracellular pathways were explored ...
Nattarika Niwetbowornchai   +8 more
openaire   +3 more sources

Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716

open access: yesActa Dermato-Venereologica, 2020
To evaluate cellular response to oncostatin M (OSM) in comparison to interleukin (IL)-31, we analyzed monocyte chemoattractant protein 1 (MCP-1) as a readout for OSM responses with and without IL-4, IL-13, anti-OSM receptor β monoclonal antibody KPL-716,
Carl D. Richards   +4 more
doaj   +1 more source

MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims This study aimed to investigate the precise mechanism and function of miR-16 in heat-denatured primary human dermal fibroblasts. Methods Primary human dermal fibroblasts were separated from normal human skin samples.
Chun Zhang   +4 more
doaj   +1 more source

Gingival fibroblasts display reduced adhesion and spreading on extracellular matrix: a possible basis for scarless tissue repair? [PDF]

open access: yesPLoS ONE, 2011
Unlike skin, oral gingiva do not scar in response to injury. The basis of this difference is likely to be revealed by comparing the responses of dermal and gingival fibroblasts to fibrogenic stimuli.
Fen Guo   +3 more
doaj   +1 more source

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