Results 21 to 30 of about 60,877 (261)

β-Ionone Attenuates Dexamethasone-Induced Suppression of Collagen and Hyaluronic Acid Synthesis in Human Dermal Fibroblasts

Biomolecules, 2021
Stress is a major contributing factor of skin aging, which is clinically characterized by wrinkles, loss of elasticity, and dryness. In particular, glucocorticoids are generally considered key hormones for promoting stress-induced skin aging through ...
Dabin Choi, Wesuk Kang, Soyoon Park, Bomin Son, Taesun Park   +4 more
doaj   +1 more source

Electrical Stimulation of Human Dermal Fibroblasts on Conducting Matrix

Technical Physics, 2022
Conducting composite based on biocompatible chitosan and single wall carbon nanotubes was used as a matrix for electrical stimulation of human fibroblasts. Parameters of ionic and electronic currents passing through the matrix upon applying cyclic potentials (±100 mV) were studied; the scaffold demonstrated high stability in the course of ...
null Yudin V.E, null Kamalov A. M., null Dresvyanina E. N., null Kodolova-Chukhontseva V. V., null Smirnova N. V., null Sapurina I. Yu., null Shishov M. A., null Kolbe K. A.   +7 more
openaire   +1 more source

Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging [PDF]

Journal of Investigative Dermatology, 2021
The aging process deleteriously alters the structure and function of dermal collagen. These alterations result in thinning, fragility, wrinkles, laxity, impaired wound healing, and a microenvironment conducive to cancer. However, the key factors responsible for these changes have not been fully elucidated, and relevant models for the study of skin ...
Taihao Quan, Yaping Xiang, Yingchun Liu, Zhaoping Qin, Yan Yang, George Bou-Gharios, John J. Voorhees, Andrzej A. Dlugosz, Gary J. Fisher   +8 more
openaire   +2 more sources

The Inhibitory Effects of Anti-Oxidants on Ultraviolet-Induced Up-Regulation of the Wrinkling-Inducing Enzyme Neutral Endopeptidase in Human Fibroblasts. [PDF]

PLoS ONE, 2016
We recently reported that the over-expression of skin fibroblast-derived neutral endopeptidase (NEP) plays a pivotal role in impairing the three-dimensional architecture of dermal elastic fibers during the biological mechanism of ultraviolet (UV)-induced
Hiroaki Nakajima, Shuko Terazawa, Takao Niwano, Yorihiro Yamamoto, Genji Imokawa   +4 more
doaj   +1 more source

Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts. [PDF]

PLoS ONE, 2017
Ageing, the progressive functional decline of virtually all tissues, affects numerous living organisms. Main phenotypic alterations of human skin during the ageing process include reduced skin thickness and elasticity which are related to extracellular ...
Wolfgang Kaisers, Petra Boukamp, Hans-Jürgen Stark, Holger Schwender, Julia Tigges, Jean Krutmann, Heiner Schaal   +6 more
doaj   +1 more source

Inonotus obliquus Extracts Decreased Expression of MMP1 mRNA via JNK-AP-1 Axis

Cosmetics, 2020
Inonotus obliquus, which is parasitic on birch and other trees, is a fungus in the family Hymenochaetaceae. In this study, we investigated whether Inonotus obliquus extracts used in traditional medicine were decreased in the expression of matrix ...
Young Joo Kim, Hwa Jun Cha
doaj   +1 more source

INVESTIGATION OF ENZYMATIC ACTIVITY IN HUMAN DERMAL FIBROBLASTS DURING VARIOUS CULTIVATION PERIODS [PDF]

Biotechnologia Acta
Aim. Research into the change in enzymatic indicators of cell activity during the aging of human dermal fibroblasts in culture from 3 to 15 passages to determine the most optimal terms for cell transplantation to patients for further cell therapy ...
A.A. TERESHCHENKO, O.K. VORONINA, Y.M. KHMELNYTSKA, D.M. PYKHTIEIEV   +3 more
doaj   +1 more source

Detection of Interleukin 1 with Human Dermal Fibroblasts

Immunobiology, 1989
A fibroblast proliferation assay was developed for the detection of interleukin 1 (IL 1). Proliferation was measured by thymidine incorporation and by staining of cellular proteins with crystal violet. Response of fibroblasts was optimal at cell numbers of 4,000 to 9,000 cells/culture and an incubation period of four days.
H, Loppnow, H D, Flad, I, Dürrbaum, J, Musehold, R, Fetting, A J, Ulmer, H, Herzbeck, E, Brandt   +7 more
openaire   +2 more sources

Chicken collagen hydrolysates differentially mediate anti-inflammatory activity and type I collagen synthesis on human dermal fibroblasts

Food Science and Human Wellness, 2018
Collagen is a major extracellular matrix protein. Given the potential anti-inflammatory and antioxidant profiles of these bioactive compounds, there has been increasing interest in using collagen derived peptides and peptide-rich collagen hydrolysates ...
Marina Offengenden, Subhadeep Chakrabarti, Jianping Wu   +2 more
doaj   +1 more source

Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms

npj Regenerative Medicine, 2020
Healing of the skin and oral mucosa utilises similar mechanisms of tissue repair, however, scarring and the rate of wound closure is vastly superior in the oral cavity suggesting differences between these two environments.
Parinaz Ahangar, Stuart J. Mills, Louise E. Smith, Stan Gronthos, Allison J. Cowin   +4 more
doaj   +1 more source