Results 11 to 20 of about 7,662,162 (290)

Interaction of Gold Nanorods with Human Dermal Fibroblasts: Cytotoxicity, Cellular Uptake, and Wound Healing

open access: yesNanomaterials, 2019
Herein, the cytotoxicity, cellular uptake and wound healing of human dermal fibroblasts were investigated upon treatment with gold nanorods (GNR) decorated with different ligands. Neutral and cationic poly ethylene glycol (PEG)-decorated GNR demonstrated
Nouf N. Mahmoud   +3 more
doaj   +4 more sources

The effect of aging in primary human dermal fibroblasts.

open access: yesPLoS ONE, 2019
Skin aging is a complex process, and alterations in human skin due to aging have distinct characteristic as compared to other organs. The aging of dermal cells and the biological mechanisms involved in this process are key areas to understand skin aging.
Juliana Carvalhães Lago   +1 more
doaj   +4 more sources

Influence of Human Dermal Fibroblasts on Epidermalization [PDF]

open access: yesJournal of Investigative Dermatology, 1989
Using a method that allowed the reconstruction of simplified living human skin in vitro, we investigated the effects of collagen texture and dermal fibroblasts on epidermal growth. Like in vivo skin, our in vitro model comprised two tissues: a dermal equivalent and an overlying epidermis.
Coulomb, Bernard   +2 more
openaire   +3 more sources

Puerarin blocks the aging phenotype in human dermal fibroblasts.

open access: yesPLoS ONE, 2021
Dermal fibroblast aging contributes to aging-associated functional defects in the skin since dermal fibroblasts maintain skin homeostasis by interacting with the epidermis and extracellular matrix.
Yuki Kamiya   +4 more
doaj   +4 more sources

Isolation and Culture of Human Dermal Fibroblasts

open access: yes, 2019
Dermal fibroblasts are the main cell type present in skin connective tissue (dermis). Fibroblasts interact with epidermal cells during hair development and in interfollicular skin. Moreover, they play an essential role during cutaneous wound healing and in bioengineering of skin. Hence, culture of primary fibroblast is gaining in importance.
Kisiel MA, Klar AS
openaire   +4 more sources

UVB irradiation on human dermal fibroblasts

open access: yes, 2023
UVB is a primary contributor to extrinsic skin aging, and a comprehensive understanding of its impact on human skin is crucial for elucidating the aging process and facilitating the development of effective drug treatments. Additionally, UVB plays a pivotal role in vitamin D synthesis within dermal fibroblasts, underscoring its positive effects on ...
Liu, Li
openaire   +2 more sources

Adhesion and Proliferation of Human Dermal Fibroblasts on Collagen Matrix

open access: yesJournal of Biomaterials Applications, 2004
The purpose of this study was to evaluate adhesion and growth of human dermal fibroblasts on a 0.150 mm-thick matrix of reconstituted collagen isolated from horse tendon. Collagen was extracted and polymerized according to the standard procedures (Opocrin, Corlo, Modena, Italy).
CROCE, Maria Antonietta   +6 more
openaire   +3 more sources

Differentiation of human dermal fibroblasts towards endothelial cells

open access: yesDifferentiation, 2013
The ultimate goal of vascular tissue engineering is the production of functional grafts for clinical use. Difficulties acquiring autologous endothelial cells have motivated the search for alternative cell sources. Differentiation of dermal fibroblasts towards several mesenchymal lineages as well as endothelial cells has been proposed.
Johan P E, Junker   +5 more
openaire   +3 more sources

Human Dermal Fibroblasts in Tissue Engineering

open access: yes, 2009
The loss or failure of tissues and/or organs is one of the most frequent problems in modern healthcare. The field of tissue engineering applies the principles of biology and engineering in order to develop functional substitutes for damaged tissues. Tissue engineering contains elements of medicine, material science and engineering with major components
Junker, Johan
core   +4 more sources

Impact of Human Dermal Microvascular Endothelial Cells on Primary Dermal Fibroblasts in Response to Inflammatory Stress [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2019
The aim of the present study was to evaluate the impact of the microenvironment produced by dermal microvascular endothelial cells, secondary to a pro-inflammatory challenge, on 2D culture models using dermal fibroblasts and in 3D reconstructed skin ...
Benjamin Sanchez   +11 more
doaj   +2 more sources

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