Results 31 to 40 of about 60,877 (261)

Regulation of PI3K/Akt dependent apoptotic markers during b virus infection of human and macaque fibroblasts. [PDF]

PLoS ONE, 2017
B virus (Macacine herpesvirus 1), a simplex virus endemic in macaques, causes encephalitis, encephalomyelitis, and death in 80% of untreated zoonotically infected humans with delayed or no treatment.
Mugdha Vasireddi, Julia K Hilliard
doaj   +1 more source

18ß-glycyrrhetinic acid derivative promotes proliferation, migration and aquaporin-3 expression in human dermal fibroblasts. [PDF]

PLoS ONE, 2017
Licorice (Glycyrrhiza) species have been widely used as a traditional medicine and a natural sweetener in foods. The 18β-glycyrrhetinic acid (18β-GA) is a bioactive compound in licorice that exhibits potential anti-cancer, anti-inflammatory, and anti ...
Chi-Feng Hung, Chien-Yu Hsiao, Wen-Hao Hsieh, Hsin-Ju Li, Yi-Ju Tsai, Chun-Nan Lin, Hsun-Hsien Chang, Nan-Lin Wu   +7 more
doaj   +1 more source

Cultured Human Dermal Fibroblasts do Produce Cortisol [PDF]

Journal of Investigative Dermatology, 2006
Known steroidogenic functions of the skin that are represented by the synthesis and metabolism of androgens and estrogens (Chen et al., 2002; Zouboulis and Degitz, 2004) probably include corticosteroids (Slominski et al., 2000; Slominski, 2005). Thus, the skin expresses both the genes and proteins involved in the synthesis of adrenal corticosteroids ...
Slominski, Andrzej, Zbytek, Blazej, Szczesniewski, Andrzej, Wortsman, Jacobo   +3 more
openaire   +2 more sources

DETERMINATION OF BIOCOMPATIBILITY AND CYTOTOXICITY OF POROUS TITANIUM-BASED MATERIALS IN EXPERIMENT

Наука и инновации в медицине, 2017
Aim - to evaluate the proliferative activity of dermal fibroblast cultures in the presence of composite materials based on titanium silicides in vitro. Materials and methods.
AV V Kolsanov, AN N Nikolaenko, VV V Ivanov, SA A Prikhodko, PV V Platonov   +4 more
doaj   +1 more source

Effect of Tazarotene, an Acetylenic Retinoid, on Human Dermal Fibroblast

Japanese Journal of Pharmacology, 1998
The inhibitory effect of tazarotene, an acetylenic retinoid, on human dermal fibroblast in vitro was compared to that of all-trans-retinoic acid. The proliferation of fibroblasts was inhibited by both retinoids at the concentration of 1 microM after 5 days of culture.
Ogawa, Akira, Maeguchi, Mizue, Uchida, Yoko, Yoshioka, Toshimasa, Kawashima, Makoto, Muraki, Takamura   +5 more
openaire   +3 more sources

Macromolecular crowding in human tenocyte and skin fibroblast cultures: A comparative analysis

Materials Today Bio
Although human tenocytes and dermal fibroblasts have shown promise in tendon engineering, no tissue engineered medicine has been developed due to the prolonged ex vivo time required to develop an implantable device.
Adrian Djalali-Cuevas, Mandy Rettel, Frank Stein, Mikhail Savitski, Stephen Kearns, Jack Kelly, Manus Biggs, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis   +11 more
doaj   +1 more source

Homogeneous Inflammatory Gene Profiles Induced in Human Dermal Fibroblasts in Response to the Three Main Species of Borrelia burgdorferi sensu lato. [PDF]

PLoS ONE, 2016
In Lyme borreliosis, the skin is the key site for bacterial inoculation by the infected tick and for cutaneous manifestations. We previously showed that different strains of Borrelia burgdorferi sensu stricto isolated from tick and from different ...
Mariam Meddeb, Wassila Carpentier, Nicolas Cagnard, Sophie Nadaud, Antoine Grillon, Cathy Barthel, Sylvie Josiane De Martino, Benoît Jaulhac, Nathalie Boulanger, Frédéric Schramm   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Magnetic gelatin-hesperidin microrobots promote proliferation and migration of dermal fibroblasts

Frontiers in Chemistry
Dermal fibroblasts play a crucial role in the formation of granulation tissue in skin wounds. Consequently, the differentiation, migration, and proliferation of dermal fibroblasts are considered key factors in the skin wound healing process.
Xuyan Sun, Hua Yang, Han Zhang, Weiwei Zhang, Chunyu Liu, Xiaoxiao Wang, Wenping Song, Lin Wang, Qingsong Zhao   +8 more
doaj   +1 more source