Results 51 to 60 of about 109,393 (302)

Homogeneous Inflammatory Gene Profiles Induced in Human Dermal Fibroblasts in Response to the Three Main Species of Borrelia burgdorferi sensu lato. [PDF]

PLoS ONE, 2016
In Lyme borreliosis, the skin is the key site for bacterial inoculation by the infected tick and for cutaneous manifestations. We previously showed that different strains of Borrelia burgdorferi sensu stricto isolated from tick and from different ...
Mariam Meddeb, Wassila Carpentier, Nicolas Cagnard, Sophie Nadaud, Antoine Grillon, Cathy Barthel, Sylvie Josiane De Martino, Benoît Jaulhac, Nathalie Boulanger, Frédéric Schramm   +9 more
doaj   +1 more source

Peptide-based microcapsules obtained by self-assembly and microfluidics as controlled environments for cell culture [PDF]

, 2013
Funding for this study was provided by the Portuguese Foundation for Science and Technology (FCT, grant PTDC/EBB-BIO/ 114523/2009). D. S. Ferreira gratefully acknowledges FCT for the PhD scholarship (SFRH/BD/44977/2008)
Aida, Allazetta, Beniash, Bott, Capito, Caplan, Chang, Cukierman, Daniela S. Ferreira, Darrabie, Friedl, Gazit, Gazit, Grzybowski, Haghgooie, Helena S. Azevedo, Jahn, Karnik, Lowik, Mendes, Mendes, Mendes, Metcalfe, Niece, Pashuck, Roeder, Rui L. Reis, Savin, Seiffert, Seliktar, Stupp, Sugihara, Velasco, Velichko, Wang, Webber, Yamada, Zhang, Zhang, Zhang, Zhou   +40 more
core   +1 more source

Macromolecular crowding in human tenocyte and skin fibroblast cultures: A comparative analysis

Materials Today Bio
Although human tenocytes and dermal fibroblasts have shown promise in tendon engineering, no tissue engineered medicine has been developed due to the prolonged ex vivo time required to develop an implantable device.
Adrian Djalali-Cuevas, Mandy Rettel, Frank Stein, Mikhail Savitski, Stephen Kearns, Jack Kelly, Manus Biggs, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis   +11 more
doaj   +1 more source

A fibrocontractive mechanochemical model of dermal wound\ud closure incorporating realistic growth factor kinetics [PDF]

, 2011
Fibroblasts and their activated phenotype, myofibroblasts, are the primary cell types involved in the contraction associated with dermal wound healing.
Hall, C. L., Maini, P. K., McCue, S. W., McElwain, D. L. S., Murphy, K. E.   +4 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Isolating human dermal fibroblasts using serial explant culture

Stem Cell Investigation, 2019
The purpose of this study was to introduce an applicable culture technique to isolate human dermal fibroblasts (HDFs); which could also contribute to research, clinical practices, as well as tissue engineering.Samples from the human skin were dissected and cultured via serial explant technique.
Fereshteh, Nejaddehbashi, Vahid, Bayati, Leila, Mashali, Mahmoud, Hashemitabar, Mohammadreza, Abbaspour, Eskandar, Moghimipour, Mahmoud, Orazizadeh   +6 more
openaire   +2 more sources

Honey exposure stimulates wound repair of human dermal fibroblasts [PDF]

Burns & Trauma, 2013
Honey is widely used for treating burns, ulcers and wounds, but the mechanisms of action are poorly known and the product is mainly used as an antimicrobial. We have examined here the wound healing properties of honey on human fibroblasts, using an in vitro scratch wound healing model. Three kinds of widely used monofloral honeys were used, viz. acacia
Ranzato, Elia, Martinotti, Simona, Burlando, Bruno   +2 more
openaire   +4 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Magnetic gelatin-hesperidin microrobots promote proliferation and migration of dermal fibroblasts

Frontiers in Chemistry
Dermal fibroblasts play a crucial role in the formation of granulation tissue in skin wounds. Consequently, the differentiation, migration, and proliferation of dermal fibroblasts are considered key factors in the skin wound healing process.
Xuyan Sun, Hua Yang, Han Zhang, Weiwei Zhang, Chunyu Liu, Xiaoxiao Wang, Wenping Song, Lin Wang, Qingsong Zhao   +8 more
doaj   +1 more source

Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues

Stem Cell Research & Therapy, 2023
Background Induced pluripotent stem cells (iPS) can be generated from various somatic cells and can subsequently be differentiated to multiple cell types of the body. This makes them highly promising for cellular therapy in regenerative medicine. However,
Hassan R. W. Ali, Salwa Suliman, Tarig Al-Hadi Osman, Manuel Carrasco, Ove Bruland, Daniela-Elena Costea, Helge Ræder, Kamal Mustafa   +7 more
doaj   +1 more source