Results 51 to 60 of about 8,808 (189)
Advanced Science, EarlyView.This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Fn14 overexpression in HDFs promotes fibroblast activation.
, 2015 (A) Cultured HDFs were transfected with pcDNA3.1 (control) or pcDNA3.1-hFn14 (p-Fn14). (B) Fn14 mRNA expression in HDFs was detected by RT–qPCR after Fn14 overexpression.
Dingzhang Xiao (832270) +13 more
core +1 more source
Cells, 2022 Human dermal fibroblasts (HDFs) have the potential to differentiate into endothelial cells (VECs). In our previous research, we reported that a hypochlorous acid (HOCl) probe CPP efficiently induced the differentiation of HDFs into VECs, however, the ...
Xiaoling Cui +7 more
doaj +1 more source
An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli
Advanced Science, EarlyView.An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni +6 more
wiley +1 more source
The Changing Character of Carbon in Fluids with Pressure
Geophysical Monograph Series, Page 259-269., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Dimitri Sverjensky +2 more
wiley +1 more source
Advanced Science, EarlyView.Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing +9 more
wiley +1 more source
Fn14 knockdown via siRNA in HDFs inhibits fibroblast activation.
, 2015 (A) Fn14 was knocked down in cultured HDFs with Fn14 siRNA, and an siRNA negative sequence was used as a control (negative control). (B) Fn14 mRNA expression was detected in Fn14 siRNA-transfected cells and control cells by RT-qPCR.
Dingzhang Xiao (832270) +13 more
core +1 more source
Advanced NanoBiomed Research, EarlyView.Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab +8 more
wiley +1 more source
Bovine vitreous gel can reactivate replicative senescence of human dermal fibroblast
Indonesian Journal of Biotechnology, 2018 The most influential factor in the poor healing of chronic ulcers is replicative senescence of fibroblasts that are unresponsive to TGF-β1 stimulation.
Maria Vianny Sansan +3 more
doaj +1 more source
Advances in Distributed Computing and Artificial Intelligence JournalThe volume of data is growing at an astonishingly high speed. Traditional techniques for storing and processing data, such as relational and centralized databases, have become inefficient and time-consuming. Linked data and the Semantic Web make internet
Wria Mohammed Salih Mohammed +1 more
doaj +1 more source