Results 61 to 70 of about 8,808 (189)

Mechanistic models for intermittent haemodialysis and haemodiafiltration clearance

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Haemodialysis has been used clinically for more than 70 years, but data regarding the clearance of medicines during dialysis are often based on studies with outdated, less efficient dialysers. Moreover, dialysis clearance is still frequently estimated using empirical approaches which lack mechanistic interpretability, are not readily generalizable ...
Laila Nassar   +2 more
wiley   +1 more source

Design and Implementation of Cloud Storage System Based on HDFS [PDF]

open access: yes, 2013
随着数据爆炸的时代到来,海量数据存储的问题也随之而来。HDFS(HadoopDistributedFileSystem)作为主流的开源云计算系统Hadoop的基础构件之一,由于其低成本、高度容错、支持大数据集等特点成为解决数据密集型应用的海量数据存储问题的首选方案之一。在HDFS越来越被广大企业重视和采用的时候,HDFS存在的一些问题也逐渐显现。首先,因为HDFS采用Master/Slaves主从架构,一旦Master节点发生故障,整个集群都无法提供服务,因此HDFS存在单点故障。其次 ...
陈蕊
core  

Design and Implementation of HDFS Data Block Scheduling Algorithm in Heterogeneous Environment [PDF]

open access: yesJisuanji gongcheng, 2017
Aiming at the insufficient of write performance of Hadoop Distributed File System(HDFS),a scheduling algorithm for concurrent transmission of HDFS data blocks in a heterogeneous environment is proposed.The algorithm monitors the resource status and ...
GAO Yuan,REN Sheng,GU Wenjie
doaj   +1 more source

Electrochemiluminescence of Heteroleptic Iridium(III) Complexes Featuring Substituted 2,4‐diphenylpyridinato Ligands

open access: yesChemistry – A European Journal, EarlyView.
Five heteroleptic iridium(III) complexes bearing cyclometalated 2,4‐diphenylpyridinato ligands were synthesized and their electrochemiluminescence (ECL) investigated. Two different coreactants were evaluated: tri‐n‐propylamine and benzoyl peroxide under anodic and cathodic potentials, respectively.
Ovini Jayawardana   +6 more
wiley   +1 more source

Alnus Sibirica Extracts Suppress the Expression of Inflammatory Cytokines Induced by Lipopolysaccharides, Tumor Necrosis Factor-α, and Interferon-γ in Human Dermal Fibroblasts

open access: yesMolecules, 2019
The effects of Alnus sibirica (AS) extracts on cytokine expression induced by inflammatory stimulants were examined in human dermal fibroblasts (HDFs) and RAW264.7 cells.
Jeongyoon Choi   +12 more
doaj   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

open access: yesDeep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu   +4 more
wiley   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

UV irradiation induces Piwil2 expression in HDFs.

open access: yes, 2013
A &B. Kinetics of Piwil2 expression in responding to DNA damage induced by UV light. HDFs were irradiated with UV (20 J/m2) and harvested at 0, 1, 2, 4, 8 and 24 h later and analyzed by Western blotting for piwil2 expression, using polyclonal rabbit ...
Li Chen (5749)   +11 more
core   +1 more source

Cellular Toxicity of Short‐ and Long‐Term Exposures to Polystyrene Nanoplastics and Microplastics in Fish Skin Cell Derived From Fathead Minnow (Pimephales promelas)

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The ubiquitous presence of microplastics and nanoplastics (MNPs) is raising concerns about their impact on the health of humans and other living organisms. Due to its tiny size, this particle can accumulate and circulate in the body after uptake, resulting in a variety of harmful outcomes on the organism, such as increased oxidative stress and
Trang Thi Nguyen   +2 more
wiley   +1 more source

ADIOS ??????????????? ????????? HDFS??? ?????? ??????

open access: yes, 2016
????????? I/O ?????? ??? ?????? ???????????????????????? ?????? ?????? ??? ?????? ????????? ?????? ?????? ????????? I/O ????????? ????????? ??? ?????? ????????? ???????????? ??????. HDFS??? ADIOS??? ???????????? ?????? JNI??? ???????????? ??????. ????????
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core  

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