Results 81 to 90 of about 19,038 (228)
Pest Management Science, EarlyView.A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos +1 more
wiley +1 more source
Responsive Materials, EarlyView.This Perspective discusses the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces in modulating cell behavior as next generation dynamic artificial scaffolds. Unlike current artificial biomaterials that have static properties, LCPs offer fast, reversible, and spatially programmable deformation that reflects the dynamic properties of ...
Ruth M. C. Verbroekken +2 more
wiley +1 more source
Small, EarlyView.Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee +14 more
wiley +1 more source
Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol
BMC Complementary and Alternative Medicine, 2018 Background Replicative senescence of human diploid fibroblasts (HDFs) has been used as a model to study mechanisms of cellular aging. Gamma-tocotrienol (γT3) is one of the members of vitamin E family which has been shown to increase proliferation of ...
Jen-Kit Tan +2 more
doaj +1 more source
Targeting Mitochondria in Melanoma
Biomolecules, 2020 Drastically elevated glycolytic activity is a prominent metabolic feature of cancer cells. Until recently it was thought that tumor cells shift their entire energy production from oxidative phosphorylation (OXPHOS) to glycolysis.
Sepideh Aminzadeh-Gohari +5 more
doaj +1 more source
A Microwell Array Embedded Microfluidic Gradient Platform for Drug Screening on Tumor Spheroids
Small, EarlyView.A microfluidic gradient platform embedded with high‐density microwell arrays (MEG platform) enables high‐throughput generation of uniform tumor spheroids for gradient‐based drug response assessment under dynamic perfusion. As a proof of concept, monoculture breast cancer cell (MCF‐7) spheroids and MCF‐7/human dermal fibroblast (HDF) co‐culture ...
Ling Liu, Guoying Wang, Ming Li
wiley +1 more source
Artificial Organs, EarlyView.We show that convective therapy in the form of hemodiafiltration does not demonstrate a measurable effect on phosphate removal in a real‐world setting. On the other hand, session duration is the most important factor in determining phosphate removal in hemodialysis patients.
David A. Jaques +4 more
wiley +1 more source
Real-Time Data Processing With Lambda Architecture [PDF]
, 2019 Data has evolved immensely in recent years, in type, volume and velocity. There are several frameworks to handle the big data applications. The project focuses on the Lambda Architecture proposed by Marz and its application to obtain real-time data ...
Malusare, Omkar Ashok
core +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Scientific Reports, 2017 MicroRNA (miR)-132 has been identified as a top up-regulated miRNA during skin wound healing and its inhibition impairs wound repair. In a human in vivo surgical wound model, we showed that miR-132 was induced in epidermal as well as in dermal wound–edge
Xi Li +6 more
doaj +1 more source