Results 191 to 200 of about 546,203 (288)

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Lipid Profile Alterations Across Coronary Heart Disease, Metabolic Syndrome, and Nephrotic Syndrome

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
CHD, MetS, and NS exhibit distinct dyslipidemia patterns. TC, TG, ApoB, ApoE, and sdLDL‐C are key markers for disease differentiation. This study found that elevated TC and sdLDL‐C were key pathogenic factors in CHD. In contrast, TG and ApoB played significant roles in the pathogenesis of MetS.
Shudong Tan   +3 more
wiley   +1 more source

Relationships between periodontitis, tooth loss, and metabolic syndrome indicators

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigates how poor oral health impacts metabolic alterations, specifically evaluating the effects of periodontitis and tooth loss, either individually or in combination, on the number of metabolic syndrome (MetS) indicators.
Verbênia Silva Conceição   +14 more
wiley   +1 more source

Association between very high HDL-C levels and cardiovascular mortality. [PDF]

open access: yesEur J Med Res
Shaikh S   +8 more
europepmc   +1 more source

Metabolic and hormonal serum markers in early childhood: Follow‐up of a randomized controlled trial during infancy evaluating a modified, low‐protein infant formula

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives High protein intake during infancy has been linked to accelerated weight gain and increased obesity risk. This study aimed to examine the effects of a low‐protein formula during the first 6 months of life on blood metabolic and hormonal markers during early childhood. Methods Formula‐fed infants (<45 days) were randomized to receive
Jacqueline Muts   +10 more
wiley   +1 more source

Turmeric and curcumin: From traditional medicine to modern therapeutic applications

open access: yesJSFA reports, EarlyView.
Abstract Turmeric (Curcuma longa), a medicinal plant, has maintained its cultural and therapeutic significance over centuries in Ayurveda, Unani, and Traditional Chinese Medicine. However, novel formulations and delivery methods are being developed to address these challenges.
Azma Nadeem   +7 more
wiley   +1 more source

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