Results 181 to 190 of about 559,929 (301)

Lipid management in type 2 diabetes and non-HDL-cholesterol: target all atherogenic lipoproteins. [PDF]

Cardiovasc Diabetol
Brandts J, Verket M, Zambon A, Marx N, Müller-Wieland D, Federici M.   +5 more
europepmc   +1 more source

The mediating roles of gut microbiota in the associations of air pollution and meteorological factors with metabolic syndrome

iMetaOmics, EarlyView.
We characterized distinct gut microbial community clusters associated with metabolic syndrome (MetS) and identified key genera underlying these patterns. Health‐associated clusters were dominated by beneficial genera such as Bacteroides and Prevotella with known metabolic protective functions.
Yixiang Huang, Wei Wu, Yuan Zheng, Hongwei Tu, Yiping Duan, Qijiong Zhu, Zhiqing Chen, Siwen Yu, Yayi Li, Wan Peng, Wenjun Ma, Tao Liu   +11 more
wiley   +1 more source

Correlation of blood lipid parameters with newly diagnosed carotid intima media thickness and carotid plaque in primary health care of populations. [PDF]

Front Cardiovasc Med
Bao T, Jin Y, Gao W.
europepmc   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Causal effect of obesity on cataract and mediating roles of metabolites: a Mendelian randomization study. [PDF]

Int J Ophthalmol
Li C, Wang JM, Yang WH.
europepmc   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Glycated High-Density Lipoproteins Reduce Endothelial Phenotypic Expression of Monocyte-Derived Multipotential Cells in Early Type 2 Diabetes. [PDF]

Metabolites
Massó-Rojas F, Montaño-Estrada LF, Páez-Arenas A, Juárez-Rojas JG, Medina-Urrutia A, Nambo-Venegas R, Rodríguez-Maldonado E, Jorge-Galarza E.   +7 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Oxylipin composition of high-density lipoprotein is altered in men and Hispanic adults with mild cognitive impairment. [PDF]

J Lipid Res
Kelliher JC, Engeland CG, Graham-Engeland JE, Katz M, Kessler C, Shearer GC.   +5 more
europepmc   +1 more source