Results 1 to 10 of about 59,863 (274)

Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2 [PDF]

Journal of Lipid Research, 2005
In this study, we tested the hypothesis that two separate pathways, the two-step process and an apolipoprotein B (apoB) size-dependent lipidation process, give rise to different lipoproteins. Expression of apoB-100 and C-terminally truncated forms of apoB-100 in McA-RH7777 cells demonstrated that VLDL particles can be assembled by apoB size-dependent ...
Pia Stillemark-Billton, Caroline Beck, Jan Borén, Sven-Olof Olofsson   +3 more
openaire   +4 more sources

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans

Journal of Lipid Research, 2003
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen, Johannes A. Romijn, Peter H. Bisschop, Martina M.J. de Barse, P.Hugh R. Barrett, Marie¨tte Ackermans, Ruud Berger, Ton J. Rabelink, Monique G.M. de Sain-van der Velden   +8 more
doaj   +2 more sources

Dysfunctional VLDL metabolism in MASLD [PDF]

npj Metabolic Health and Disease
AbstractLipidomics has unveiled the intricate human lipidome, emphasizing the extensive diversity within lipid classes in mammalian tissues critical for cellular functions. This diversity poses a challenge in maintaining a delicate balance between adaptability to recurring physiological changes and overall stability.
Urko M. Marigorta, Oscar Millet, Shelly C. Lu, José M. Mato   +3 more
openaire   +6 more sources

Plasma lipoprotein metabolism in lean and in fat chickens produced by divergent selection for plasma very low density lipoprotein concentration.

Journal of Lipid Research, 1989
Plasma lipoprotein metabolism was studied in vivo in two lines of chickens produced by selection for high and low plasma very low density lipoprotein (VLDL) concentration.
H Griffin, F Acamovic, K Guo, J Peddie
doaj   +1 more source

Systemic Review to Explore the Effect of Dyslipidaemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus: In Tertiary Care Center

Journal of Pharmacy and Bioallied Sciences
Metabolic dyslipidemia (high triglyceride) and low high-density lipoprotein cholesterol (HDL-C) are highly prevalent in type 2 diabetes mellitus (T2DM).
Akansha Singh, Ranjit S. Ambad, Roshan K. Jha   +2 more
doaj   +1 more source

Lipolytic remnants of human VLDL produced in vitro: effect of HDL levels in the lipolysis mixtures on the apoCs to apoE ratio and metabolic properties of VLDL core remnants

Journal of Lipid Research, 2000
To determine the role of high-density lipoprotein (HDL) as an acceptor of lipolytic surface remnants of very low density lipoprotein (VLDL) in the metabolism of VLDL core remnants, we examined the effect of HDL levels in the VLDL lipolysis mixture on 1 ...
Byung Hong Chung, Nassrin Dashti
doaj   +1 more source

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.

Journal of Lipid Research, 1996
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this study, a
J Bjorkegren, C J Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe   +8 more
doaj   +1 more source

Adipocytokines and VLDL Metabolism [PDF]

Diabetes, 2005
We investigated the relationship of plasma adipocytokine concentrations with VLDL apolipoprotein B (apoB)-100 kinetics in men. Plasma adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) concentrations were measured using enzyme immunoassays and insulin resistance by homeostasis model assessment (HOMA) score in 41 ...
Theodore W.K. Ng, Gerald F. Watts, Maryam S. Farvid, Dick C. Chan, P. Hugh R. Barrett   +4 more
openaire   +1 more source

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

Journal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry, T Olivecrona, R J Deckelbaum, S Eisenberg   +3 more
doaj   +1 more source

Characterization of very low density lipoprotein from Watanabe heritable hyperlipidemic rabbits.

Journal of Lipid Research, 1989
We investigated the properties of very low density lipoprotein (VLDL) from two types of Watanabe heritable hyperlipidemic (WHHL) rabbits: one with a high incidence of coronary atherosclerosis (type 1), and the other with a low incidence (type 2).
K Ishii, T Kita, M Yokode, N Kume, Y Nagano, H Otani, T Yamamura, S Murayama, Y Morimoto, Y Teranishi   +9 more
doaj   +1 more source